내시경 점막하 박리술을 통해 진단, 치료한 위 림프상피종양 암종 1예
Gastric Lymphoepithelioma-like Carcinoma Diagnosed and Treated by Endoscopic Submucosal Dissection: Review of the Literature
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초록
위의 림프상피종양 암종은 위암의 드문 형태로 림프 모양 조직 배경에 미분화된 악성 종양 세포가 침윤하는 특징을 보인다. 흔히 보이는 위샘암에 비해 예후가 비교적 좋고 Epstein- Barr 바이러스 감염과 높은 연관성을 보인다. 저자들은 57세 여자 환자에서 육안적으로 궤양형 조기위암 형태를 보이나 반복적인 생검에서는 음성이었던 환자에서 진단과 근치적 절제를 목적으로 내시경 점막하 박리술을 시행하여 위 림프상피종양 암종을 확진한 1예를 경험하였기에 문헌 고찰과 함께 보고한다.
Abstract
Gastric lymphoepithelioma-like carcinoma (LELC) is a rare neoplasm of the stomach that features undifferentiated carcinoma mixed with lymphoid stroma, and it invariably has a good prognosis. Most gastric LELCs have been linked to Epstein-Barr virus (EBV) infection. We experienced a case of a patient with gastric LELC. A 57 years old female patient was found to have shallow irregular ulcerative lesion on the gastric antrum. Although repetitive endoscopic biopsy didn’t yield any cancer, early gastric cancer (EGC) was strongly suspected. Endoscopic submucosal dissection (ESD) was performed for establishing the correct diagnosis and curatively resecting the lesion. The pathology revealed gastric LELC with vertical invasion to the submucosa. No remnant cancer and no lymph node metastasis were noted after surgery following ESD. Here, we are reporting on a case of gastric ELEC along with reviewing the relevant literature. We believe this is the first case of gastric ELEC that was successfully diagnosed and managed by ESD.
참고문헌 (20)
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