담관 유두종증 환자에서 광역동치료 후 발생한 양성 담관협착 1예
A Case of Benign Biliary Stricture as a Complication of Photodynamic Therapy for Biliary Papillomatosis
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초록
담관 유두종증은 매우 드문 질환이며, 재발률이 높고, 악성으로 변하는 전암 병변이기 때문에 근치적 절제술이 필요하다. 하지만, 여러 가지 이유로 수술적 치료가 어려운 경우에는 보존적 치료를 선택해야 한다. 광역동치료는 담관 유두종증의 새로운 유망한 보존적 치료로 안전성과 효과면에서 기존의 것에 비해 우월한 것으로 보인다. 하지만 광역동치료가 안정성과 생존율 그리고 삶의 질 향상에 미치는 영향에 대해서는 좀 더 많은 연구가 필요하다. 저자들은 간내ㆍ외 담관에 미만성으로 분포한 담관유두종증 환자에게 보존적 치료로써 시행한 광역동치료 후 양성 담관협착이 발생하여 문헌 고찰과 함께 보고한다.
Abstract
Biliary papillomatosis is a rare disease with a high risk of recurrence and malignant transformation. Therapeutic options include partial hepatectomy, Whipple’s procedure and liver transplantation. If there is no surgical option left due to several reasons, local palliative procedures such as biliary stenting and drainage for the treatment of cholestasis are considered, but tumor growth cannot be influenced. Photodynamic therapy might be a new additional, palliative option for patients with biliary papillomatosis who are not eligible for surgery. Benign biliary stricture is a rare complication of photodynamic therapy. We report here a case of a 63-year-old male who developed benign biliary stricture after photodynamic therapy using the photosensitizer photofrin.
참고문헌 (19)
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