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순환기 내과 환자를 대상으로 한 심부전의 정도와 NT-pro BNP의 혈중 농도와의 관계 분석 : 순환기 내과 외래 환자와 입원 환자를 중심으로

Correlation between levels of n-terminal pro-b-type natriuretic peptide and degrees of heart failure

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참고문헌

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초록

Abstract

Background : N-terminal fragment of pro Brain Natriuretic Peptide (NT-pro BNP) is a neuro-hormone synthesized from the cardiac ventricles in response to increased wall tension. The purpose of this study was to assess the correlation between NT-pro BNP levels and New York Heart Association function class (NYHA Fc) and echocardiographic findings in patients, who visited cardiology department. Methods : From October, 2002 to April, 2003, serum NT-pro BNP levels were measured in 348 patients, who visited Samsung Medical Center and Jong Koo Lee Heart Clinic. Results : NT-pro BNP levels were increased with the progression of NYHA Fc of dyspnea (p<0.001 by ANOVA) as well as with the increase in systolic left ventricular internal dimension (p<0.05) and the decrease in ejection fraction (p<0.01). In NYHA Fc I patients, NT-pro BNP levels of NT-pro BNP level appears to be a sensitive level to differentiate dyspnea of heart origin or not in patients, who visited cardiology department.

참고문헌 (24)

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