심부전 관련 Biomarkers: BNP를 중심으로
Biomarkers in Heart Failure: Focus on B-type Natriuretic Peptide
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초록
현재 여러 연구결과 BNP와 NT-proBNP가 심부전을 진단하는 진단적 가치가 높은 검사임에는 분명하고 실제 임상에서 응급실 혹은 외래 진료 시 객관적이고 분별력 있는(objective and ‘rule out’ test) 검사로서 유용할 것이라 생각된다. 하지만 BNP가 단독(stand-alone) 진단도구가 아니고 환자의 임상적 상황을 고려하여 판단하는 것이 중요할 것이라 생각된다. 또한 중요한 예후인자로 심부전의 진단 및 치료의 중요한 지침이 될 것으로 생각된다.
Abstract
Assays for B-type natriuretic peptide (BNP) or N-terminal pro-brain BNP (NTproBNP) BNP are useful diagnostic method for evaluation of patients with dyspnea. And, natriuretic peptide levels have important prognostic value in heart failure. Therefore, measurements of BNP or NT-proBNP, taken together with conventional clinical assessment, may assist in the decision of treatment process. The following brief review summarizes available information concerning clinical significance of BNP or NT-proBNP. (Korean J Med 2012;82:647-650)
참고문헌 (7)
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