Gastric Syphilis and Membranous Glomerulonephritis
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Syphilis is a chronic systemic infectious disease caused by the bacterium Treponema pallidum. Gastric involvement and nephrotic syndrome are uncommon but well documented complications of syphilis, but the co-occurrence of these two complications in the same patient is extremely rare. Thus, because of their nonspecific presentation, suspicion of gastric syphilis (GS) and nephrotic syndrome is essential for diagnosis. Patients should be investigated thoroughly and a diagnosis made based on clinical, endoscopic, and histological findings, in order to initiate appropriate therapy. We report of a 34-year-old male patient with a history of epigastric pain and a diagnosis of GS and syphilis-associated membranous glomerulonephritis confirmed by gastroscopy and kidney biopsy, who was treated successfully with penicillin G benzathine. This case report provides information on the typical features of GS that should help raise awareness of this rare disease entity among clinicians, resulting in earlier diagnosis and administration of appropriate therapy.
Abstract
Syphilis is a chronic systemic infectious disease caused by the bacterium Treponema pallidum. Gastric involvement and nephrotic syndrome are uncommon but well documented complications of syphilis, but the co-occurrence of these two complications in the same patient is extremely rare. Thus, because of their nonspecific presentation, suspicion of gastric syphilis (GS) and nephrotic syndrome is essential for diagnosis. Patients should be investigated thoroughly and a diagnosis made based on clinical, endoscopic, and histological findings, in order to initiate appropriate therapy. We report of a 34-year-old male patient with a history of epigastric pain and a diagnosis of GS and syphilis-associated membranous glomerulonephritis confirmed by gastroscopy and kidney biopsy, who was treated successfully with penicillin G benzathine. This case report provides information on the typical features of GS that should help raise awareness of this rare disease entity among clinicians, resulting in earlier diagnosis and administration of appropriate therapy.
참고문헌 (13)
- Mylona EE, "Gastric syphilis: a systematic review of published cases of the last 50 years", Sex Transm Dis, 37, pp.177~183 (2010)
- Hook EW, "Acquired syphilis in adults", N Engl J Med, 326, pp.1060~1069 (1992)
- "Disease web statics system: syphilis" (2002)[URL]
- Souza Varella Frazão M, "Endoscopic aspects of gastric syphilis", Case Rep Med, 2012, pp.646525~ (2012)
- Hunte W, "Secondary syphilis and the nephrotic syndrome", J Am Soc Nephrol, 3, pp.1351~1355 (1993)
- Handoko ML, "Syphilis: a reversible cause of nephrotic syndrome", BMJ Case Rep, 2013 (2013)
- Fujisaki T, "A case of gastric syphilis", Clin Gastroenterol Hepatol, 6, pp.A34~ (2008)
- Greenstein DB, "Gastric syphilis. Report of seven cases and review of the literature", J Clin Gastroenterol, 18, pp.4~9 (1994)
- Anai H, "Gastric syphilis simulating linitis plastica type of gastric cancer", Gastrointest Endosc, 36, pp.624~626 (1990)
- Abdu RA, "Gastric syphilis mimicking linitis plastica", Arch Surg, 128, pp.103~104 (1993)
- Winters HA, "Gastric syphilis: five recent cases and a review of the literature", Ann Intern Med, 116, pp.314~319 (1992)
- Tang AL, "Nephrotic syndrome and hepatitis in early syphilis", Postgrad Med J, 65, pp.14~15 (1989)
- 권현희, "위장, 간 침범과 함께 막성 신병증이 합병된 제2기 매독1예", Kidney Research and Clinical Practice, 23(1), pp.152~157 (2004), 대한신장학회