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Two Cases of Russell Body Gastritis Treated by Helicobacter pylori Eradication

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Russell body gastritis was first defined in 1998, but not many cases have been reported since then. The exact causes and process of this condition are unknown yet; however, considering the reported cases, it has been highly suggested to have correlation with Helicobacter pylori infection. Russell body gastritis has a non-specific clinical presentation of gastritis such as gastric mucosal edema in the macroscopic view. It can be mistaken as xanthoma, signet ring cell carcinoma, or a malignant lymphoma including mucosa-associated lymphoid tissue lymphoma and plasmocytoma. Russell body gastritis features polyclonal immunoglobulin and is differentiated from Mott cancer, of which immune globulin has monoclonal aspect. Authors report here two cases of Russell body gastritis with examined endoscopic findings as well as a review of related literature on the association of all reported cases of Russell body gastritis with H. pylori infection.

Abstract

Russell body gastritis was first defined in 1998, but not many cases have been reported since then. The exact causes and process of this condition are unknown yet; however, considering the reported cases, it has been highly suggested to have correlation with Helicobacter pylori infection. Russell body gastritis has a non-specific clinical presentation of gastritis such as gastric mucosal edema in the macroscopic view. It can be mistaken as xanthoma, signet ring cell carcinoma, or a malignant lymphoma including mucosa-associated lymphoid tissue lymphoma and plasmocytoma. Russell body gastritis features polyclonal immunoglobulin and is differentiated from Mott cancer, of which immune globulin has monoclonal aspect. Authors report here two cases of Russell body gastritis with examined endoscopic findings as well as a review of related literature on the association of all reported cases of Russell body gastritis with H. pylori infection.

참고문헌 (13)

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  8. Hsu SM, "Russell bodies: a light and electron microscopic immunoperoxidase study", Am J Clin Pathol, 77, pp.26~31 (1982)
  9. 엄성우, "헬리코박터 파이로리 감염을 동반한 Russell 소체 위염 1예", Clinical Endoscopy, 35(3), pp.181~185 (2007), 대한소화기내시경학회
  10. Johansen A, "The diagnostic significance of Russell bodies in endoscopic gastric biopsies", Acta Pathol Microbiol Scand A, 85, pp.245~250 (1977)
  11. Erbersdobler A, "Russell body gastritis: an unusual, tumor- like lesion of the gastric mucosa", Arch Pathol Lab Med, 128, pp.915~917 (2004)
  12. Drut R, "Images in pathology. Russell body gastritis in an HIV-positive patient", Int J Surg Pathol, 14, pp.141~142 (2006)
  13. Del Gobbo A, "Helicobacter pylori-negative Russell body gastritis: case report", World J Gastroenterol, 17, pp.1234~1236 (2011)

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