본문 바로가기
KERD
논문KCI 등재

The Role of Capsule Endoscopy in Patients with Obscure Gastrointestinal Bleeding

Yang Won Min|Dong Kyung Chang
대한소화기내시경학회 (The Korean Society Of Gastrointestinal Endoscopy)|2016.01|Clinical Endoscopy|제49권 제1호|pp. 16-20

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

DiagnosisOutcomeCapsule endoscopyObscure gastrointestinal bleeding
주제분류내과학

초록

Obscure gastrointestinal bleeding (OGIB) accounts for 5% of all gastrointestinal (GI) bleeding cases and is often caused by small bowel lesions. Capsule endoscopy (CE), which allows non-invasive visualization of the small bowel mucosa, has revolutionized the evaluation of OGIB. CE is preferred by both patients and physicians mainly because of its non-invasiveness, and is widely used as the first-line diagnostic modality for OGIB. The diagnostic yield of CE in OGIB has been reported to be in the range of 32% to 83%. Although no direct comparison has been made, a meta-analysis showed similar diagnostic yields between CE and double-balloon enteroscopy (DBE) for OGIB. However, CE could enhance the yield of subsequent DBE and serve as a guide for optimizing the insertion route for DBE. Even after negative CE, selected patients could benefit from second-look CE for OGIB. In terms of outcomes, a favorable clinical impact after CE has been reported in several studies. However, observations indicate that CE might not influence clinical outcomes directly, but rather play a role in selecting patients with OGIB who are likely to benefit from subsequent evaluation and intervention.

Abstract

Obscure gastrointestinal bleeding (OGIB) accounts for 5% of all gastrointestinal (GI) bleeding cases and is often caused by small bowel lesions. Capsule endoscopy (CE), which allows non-invasive visualization of the small bowel mucosa, has revolutionized the evaluation of OGIB. CE is preferred by both patients and physicians mainly because of its non-invasiveness, and is widely used as the first-line diagnostic modality for OGIB. The diagnostic yield of CE in OGIB has been reported to be in the range of 32% to 83%. Although no direct comparison has been made, a meta-analysis showed similar diagnostic yields between CE and double-balloon enteroscopy (DBE) for OGIB. However, CE could enhance the yield of subsequent DBE and serve as a guide for optimizing the insertion route for DBE. Even after negative CE, selected patients could benefit from second-look CE for OGIB. In terms of outcomes, a favorable clinical impact after CE has been reported in several studies. However, observations indicate that CE might not influence clinical outcomes directly, but rather play a role in selecting patients with OGIB who are likely to benefit from subsequent evaluation and intervention.

참고문헌 (57)

  1. Raju GS, "American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding", Gastroenterology, 133, pp.1697~1717 (2007)
  2. Pennazio M, "ICCE consensus for obscure gastrointestinal bleeding", Endoscopy, 37, pp.1046~1050 (2005)
  3. Lin S, "Obscure gastrointestinal bleeding", Gastroenterol Clin North Am, 34, pp.679~698 (2005)
  4. Tang SJ, "Capsule endoscopy in obscure gastrointestinal bleeding", Gastrointest Endosc Clin N Am, 14, pp.87~100 (2004)
  5. Iddan G, "Wireless capsule endoscopy", Nature, 405, pp.417~ (2000)
  6. Ell C, "The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding", Endoscopy, 34, pp.685~689 (2002)
  7. Voderholzer WA, "Diagnostic yield of wireless capsule enteroscopy in comparison with computed tomography enteroclysis", Endoscopy, 35, pp.1009~1014 (2003)
  8. Costamagna G, "A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease", Gastroenterology, 123, pp.999~1005 (2002)
  9. Hara AK, "Small bowel: preliminary comparison of capsule endoscopy with barium study and CT", Radiology, 230, pp.260~265 (2004)
  10. Triester SL, "A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding", Am J Gastroenterol, 100, pp.2407~2418 (2005)
  11. Leighton JA, "Capsule endoscopy: a meta-analysis for use with obscure gastrointestinal bleeding and Crohn’s disease", Gastrointest Endosc Clin N Am, 16, pp.229~250 (2006)
  12. 심기남, "Guideline for Capsule Endoscopy: Obscure Gastrointestinal Bleeding", Clinical Endoscopy, 46(1), pp.45~53 (2013), 대한소화기내시경학회
  13. ASGE Standards of Practice Committee, "The role of endoscopy in the management of obscure GI bleeding", Gastrointest Endosc, 72, pp.471~479 (2010)
  14. Concha R, "Obscure gastrointestinal bleeding: diagnostic and therapeutic approach", J Clin Gastroenterol, 41, pp.242~251 (2007)
  15. Mylonaki M, "Wireless capsule endoscopy:a comparison with push enteroscopy in patients with gastroscopy and colonoscopy negative gastrointestinal bleeding", Gut, 52, pp.1122~1126 (2003)
  16. Mata A, "Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy", Aliment Pharmacol Ther, 20, pp.189~194 (2004)
  17. Rastogi A, "Diagnostic yield and clinical outcomes of capsule endoscopy", Gastrointest Endosc, 60, pp.959~964 (2004)
  18. Calabrese C, "Obscure gastrointestinal bleeding: single centre experience of capsule endoscopy", Intern Emerg Med, 8, pp.681~687 (2013)
  19. Iwamoto J, "The clinical outcome of capsule endoscopy in patients with obscure gastrointestinal bleeding", Hepatogastroenterology, 58, pp.301~305 (2011)
  20. Goenka MK, "Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding", World J Gastroenterol, 17, pp.774~778 (2011)
  21. Zhang BL, "Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding", World J Gastroenterol, 15, pp.5740~5745 (2009)
  22. Carey EJ, "A single-center experience of 260consecutive patients undergoing capsule endoscopy for obscure gastrointestinal bleeding", Am J Gastroenterol, 102, pp.89~95 (2007)
  23. Liao Z, "Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review", Gastrointest Endosc, 71, pp.280~286 (2010)
  24. Katsinelos P, "The role of capsule endoscopy in the evaluation and treatment of obscure-overt gastrointestinal bleeding during daily clinical practice: a prospective multicenter study", Scand J Gastroenterol, 49, pp.862~870 (2014)
  25. Min YW, "Long-term outcome of capsule endoscopy in obscure gastrointestinal bleeding: a nationwide analysis", Endoscopy, 46, pp.59~65 (2014)
  26. Riccioni ME, "Negative capsule endoscopy in patients with obscure gastrointestinal bleeding reliable: recurrence of bleeding on long-term follow-up", World J Gastroenterol, 19, pp.4520~4525 (2013)
  27. Teshima CW, "Double balloon enteroscopy and capsule endoscopy for obscure gastrointestinal bleeding:an updated meta-analysis", J Gastroenterol Hepatol, 26, pp.796~801 (2011)
  28. Pennazio M, "Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100consecutive cases", Gastroenterology, 126, pp.643~653 (2004)
  29. Ge ZZ, "Best candidates for capsule endoscopy for obscure gastrointestinal bleeding", J Gastroenterol Hepatol, 22, pp.2076~2080 (2007)
  30. Selby W, "Can clinical features predict the likelihood of finding abnormalities when using capsule endoscopy in patients with GI bleeding of obscure origin?", Gastrointest Endosc, 59, pp.782~787 (2004)
  31. Redondo-Cerezo E, "Diagnostic yield and impact of capsule endoscopy on management of patients with gastrointestinal bleeding of obscure origin", Dig Dis Sci, 52, pp.1376~1381 (2007)
  32. Sidhu R, "Factors predicting the diagnostic yield and intervention in obscure gastrointestinal bleeding investigated using capsule endoscopy", J Gastrointestin Liver Dis, 18, pp.273~278 (2009)
  33. Bresci G, "The role of video capsule endoscopy for evaluating obscure gastrointestinal bleeding: usefulness of early use", J Gastroenterol, 40, pp.256~259 (2005)
  34. Esaki M, "Factors associated with the clinical impact of capsule endoscopy in patients with overt obscure gastrointestinal bleeding", Dig Dis Sci, 55, pp.2294~2301 (2010)
  35. May A, "Influence of patient selection on the outcome of capsule endoscopy in patients with chronic gastrointestinal bleeding", J Clin Gastroenterol, 39, pp.684~688 (2005)
  36. Parikh DA, "Improved diagnostic yield with severity of bleeding", J Dig Dis, 12, pp.357~363 (2011)
  37. Estévez E, "Diagnostic yield and clinical outcomes after capsule endoscopy in 100 consecutive patients with obscure gastrointestinal bleeding", Eur J Gastroenterol Hepatol, 18, pp.881~888 (2006)
  38. Kaffes AJ, "Clinical outcomes after double-balloon enteroscopy in patients with obscure GI bleeding and a positive capsule endoscopy", Gastrointest Endosc, 66, pp.304~309 (2007)
  39. Gay G, "Outcome of capsule endoscopy in determining indication and route for push-and-pull enteroscopy", Endoscopy, 38, pp.49~58 (2006)
  40. Li X, "Predictive role of capsule endoscopy on the insertion route of double-balloon enteroscopy", Endoscopy, 41, pp.762~766 (2009)
  41. Svarta S, "Diagnostic yield of repeat capsule endoscopy and the effect on subsequent patient management", Can J Gastroenterol;, 24, pp.441~444 (2010)
  42. Viazis N, "Is there a role for second-look capsule endoscopy in patients with obscure GI bleeding after a nondiagnostic first test?", Gastrointest Endosc, 69, pp.850~856 (2009)
  43. Ben Soussan E, "Diagnostic yield and therapeutic implications of capsule endoscopy in obscure gastrointestinal bleeding", Gastroenterol Clin Biol, 28, pp.1068~1073 (2004)
  44. Katsinelos P, "Diagnostic yield and clinical impact of capsule endoscopy in obscure gastrointestinal bleeding during routine clinical practice: a single-center experience", Med Princ Pract, 20, pp.60~65 (2011)
  45. Hindryckx P, "Clinical impact of capsule endoscopy on further strategy and long-term clinical outcome in patients with obscure bleeding", Gastrointest Endosc, 68, pp.98~104 (2008)
  46. Park JJ, "Negative capsule endoscopy without subsequent enteroscopy does not predict lower long-term rebleeding rates in patients with obscure GI bleeding", Gastrointest Endosc, 71, pp.990~997 (2010)
  47. Tan W, "Long-term outcome in patients with obscure gastrointestinal bleeding after capsule endoscopy", J Dig Dis, 16, pp.125~134 (2015)
  48. Lai LH, "Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy", Am J Gastroenterol, 101, pp.1224~1228 (2006)
  49. Macdonald J, "Negative capsule endoscopy in patients with obscure GI bleeding predicts low rebleeding rates", Gastrointest Endosc, 68, pp.1122~1127 (2008)
  50. Koh SJ, "Long-term outcome in patients with obscure gastrointestinal bleeding after negative capsule endoscopy", World J Gastroenterol, 19, pp.1632~1638 (2013)
  51. Xin L, "Indications, detectability, positive findings, total enteroscopy, and complications of diagnostic double-balloon endoscopy: a systematic review of data over the first decade of use", Gastrointest Endosc, 74, pp.563~570 (2011)
  52. Richter JM, "Angiodysplasia. Natural history and efficacy of therapeutic interventions", Dig Dis Sci, 34, pp.1542~1546 (1989)
  53. Saurin JC, "Clinical impact of capsule endoscopy compared to push enteroscopy: 1-year follow-up study", Endoscopy, 37, pp.318~323 (2005)
  54. Magalhães-Costa P, "Re-bleeding events in patients with obscure gastrointestinal bleeding after negative capsule endoscopy", World J Gastrointest Endosc, 7, pp.403~410 (2015)
  55. Samaha E, "Long-term outcome of patients treated with double balloon enteroscopy for small bowel vascular lesions", Am J Gastroenterol, 107, pp.240~246 (2012)
  56. May A, "Long-term outcome after argon plasma coagulation of small-bowel lesions using double-balloon enteroscopy in patients with mid-gastrointestinal bleeding", Endoscopy, 43, pp.759~765 (2011)
  57. Endo H, "Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding", BMC Gastroenterol, 8, pp.12~ (2008)

관련 논문AI추천

Should Capsule Endoscopy Be the First Test for Every Obscure Gastrointestinal Bleeding?태정현, Ki-Nam Shim대한소화기내시경학회 · Clinical Endoscopy2014 · 제47권 제5호Diagnosis of Obscure Gastrointestinal BleedingSatoshi Tanabe대한소화기내시경학회 · Clinical Endoscopy2016 · 제49권 제6호Review of small bowel capsule endoscopy for diagnosis of gastrointestinal bleedingOh Dong Jun소화기인터벤션의학회 · International Journal of Gastrointestinal Intervention2025 · 제14권 제3호Does Back-To-Back Capsule Endoscopy Increase the Diagnostic Yield over a Single Examination in Patients with Obscure Gastrointestinal Bleeding?김범진, 민병훈, 이인석, 창동경, 최명규거트앤리버 소화기연관학회협의회 · Gut and Liver2010 · 제4권 제1호Roles of Capsule Endoscopy and Balloon-Assisted Enteroscopy in the Optimal Management of Small Bowel BleedingAlan Kawarai Lefor, Hani Abutalib, Hironori Yamamoto, Satoshi Shinozaki, Tomonori Yano대한소화기내시경학회 · Clinical Endoscopy2020 · 제53권 제4호Current Status of Interpretation of Small Bowel Capsule EndoscopyDong-Hoon Yang, Jin Su Kim, Su Hwan Kim대한소화기내시경학회 · Clinical Endoscopy2018 · 제51권 제4호

이 간행물의 다른 논문 (7건)

Obscure Gastrointestinal Bleeding: Capsule or Balloon?이보인pp. 4-5Current Status and Research into Overcoming Limitations of Capsule EndoscopyYun Jeong Lim, Won Gun Kwackpp. 8-15The Usefulness of Capsule Endoscopy for Small Bowel Tumors최명규, 심기남, 김진수, 정대영pp. 21-25Challenges and Future of Wireless Capsule EndoscopyChristine Chambon, Jean-Christophe Saurin, Nicolas Beneche, Mathieu Piochepp. 26-29Application and Efficacy of Super-Magnifying Endoscopy for the Lower Intestinal TractHaruhiko Ogata, Naoki Hosoepp. 37-40
원문 보기