갑상선 미분화암으로 오인된 전이성 폐암
Metastatic lung cancer mimicking anaplastic thyroid cancer
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
본 증례는 임상적으로나 조직학적으로 두 질환간의 감별이 어렵고, 현재까지도 환자의 모든 방사선검사 결과는 갑상선암의 폐전이로 보고되고 있다. 단지 경부조직 및 폐렴부위에서 시행한 면역조직화학검사를 통해 두 질환을 감별할 수 있었다. 이러듯 갑상선 전이암과 갑상선 원발암의 감별이 어려운 경우는 비교적 드물게 발생되어, 국내에는 이에 대한 사례보고가 아직 없지만 외국에는 1사례가 보고되고 있다19). 이에 저자들은 44세의 갑상선 미분화암으로 오인된 폐선암의 갑상선 전이 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Anaplastic thyroid cancer is the most aggressive form of cancer found in humans. Usually it is easily diagnosed; however at times other diseases are mistaken for anaplastic thyroid cancer. We present a case of primary lung adenocarcinoma presenting with features that appeared as anaplastic thyroid cancer. The 43-year-old female patient was diagnosed with anaplastic thyroid cancer at a local clinic just before presenting to our hospital. At the clinic she had a neck node excisional biopsy and was informed of the diagnosis of anaplastic cancer. On admission to our hospital, very large bilateral thyroid masses, and lymphadenopathy involving multiple cervical lymph nodes was observed; therefore, we started chemoradiotherapy. The patient showed dramatic improvement and we began to think of other potential etiologies. A FDG-PET study showed increased uptake at the left lower lung area corresponding to a pneumonic consolidation; a TBLB was performed, and reported as poorly differentiated adenocarcinoma. We referred the patient to the oncology department. The patient died after two cycles of systemic chemotherapy.(Korean J Med 71:316-321, 2006)
참고문헌 (18)
- "Anaplastic transformation of thyroid cancer: review of clinical, pathologic and molecular evidence provides new insights into disease biology and future therapy", 25, pp.662~670 (2003)
- "Treatment of 37 patients with anaplastic carcinoma of the thyroid", 18, pp.36~41 (1996)
- "Severe thyrotoxicosis induced by thyroid metastasis of lung adenocarcinoma:a case report and review of literature", 11, pp.883~888 (2001)
- "International classification of disease for oncology" (1990)
- "Glandular patterns in a thyroid carcinoma with insular and anaplastic features:a case with possible implications for the classification of thyroid carcinomas", 6, pp.389~398 (2002)
- "Guides to clinical aspiration biopsy , thyroid.", pp.233~250 (1996), IGAKU-SHOIN medical publishers
- "Fine-needle aspiration cytology diagnosis of non Hodgkinlymphoma of thyroid:a report of o four cases", 9, pp.639~645 (1993)
- "Metastases to the thyroid gland:a report of 43 cases", 79, pp.574~578 (1997)
- "Completely resected anaplastic thyroid carcinoma combined with adjuvant chemotherapy and irradiation is associated with prolonged survival", 91, pp.2335~2342 (2001)
- "Anaplastic giant cell carcinoma of the thyroid glan:treatment and survival over a 25-year period", 22, pp.725~730 (1998)
- "Anaplastic thyroid cancer", 15, pp.78~83 (2003)
- "Anaplastic thyroid carcinoma:91 patients treated by surgery and radiotherapy", 18, pp.83~88 (1992)
- "Anaplastic carcinoma of the thyroid", 177, pp.337~339 (1999)
- "Metastatic tumors in the thyroid gland", 7, pp.187~208 (2004)
- "Les Metastases thyroidiennes", 126, pp.981~984 (2001)
- "Metastatic tumors of the thyroid gland:a study of 79 cases in Chinese patients", 122, pp.37~41 (1998)
- "Clinically significant, isolated metastatic disease to the thyroid gland.", 23, pp.177~181 (1999)
- "Metastasis to the thyroid from lung adenocarcinoma mimicking thyroid carcinoma", 52, pp.353~356 (2004)