원발성 폐 악성 흑색종의 진단과 치료 1예
Diagnosis and management of primary malignant melanoma of the lung: a case report
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저자들은 악성 흑색종의 원발 부위로 흔치 않은 폐 악성 흑색종 환자에서 원발 부위의 수술적 치료 및 전이 부위에 대한 수술적 치료와 보조적 치료를 통해 생존기간을 연장시킨 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
Melanoma develops in the skin or the mucosa of organs. It spreads via lymphatic channels or the bloodstream to the regional lymph nodes or organs such as the brain, liver, and lung. Melanoma of the lung is nearly always metastatic, and primary malignant melanoma of the lung is very rare, with only 30 cases reported in the English literature. The possibility of skin lesions that have disappeared, or of undetected primary sites, makes it difficult to confirm true primary tumors. Therefore, a thorough workup is needed to make the diagnosis. Since metastatic melanoma is incurable, the goal of treatment is palliation. However, because of the rare experience of primary melanoma of the lung, it is difficult to predict the prognosis. We experienced one patient with primary malignant melanoma of the lung with metastases who had been managed with surgery, interferon-α, chemotherapy, and radiation therapy over 5 years. This case report presents the diagnosis and management of primary malignant melanoma of the lung.
참고문헌 (20)
- Dountsis A, "Primary malignant melanoma of the lung: a case report", World J Surg Oncol, 1, pp.26~ (2003)
- Farrell DJ, "Primary malignant melanoma of the bronchus", Thorax, 51, pp.223~224
- Todd FW, "Two cases of melanotic tumor in the lungs", JAMA, 11, pp.53~54 (1888)
- Ost D, "Primary pulmonary melanoma: case report and literature review", Mayo Clin Proc, 74, pp.62~66 (1999)
- Littman CD, "Metastatic melanoma mimicking primary bronchial melanoma", Histopathology, 18, pp.561~563 (1991)
- Wöckel W, "Primary bronchial malignant melanoma", Pathologe, 19, pp.299~304 (1998)
- Cahan WG, "Excision of melanoma metastases to lung: problems in diagnosis and management", Ann Surg, 178, pp.703~709 (1973)
- McGovern VJ, "Spontaneous regression of melanoma", Pathology, 7, pp.91~99 (1975)
- Ozdemir N, "Primary malignant melanoma of the lung in oculocutaneous albino patient", Eur J Cardiothorac Surg, 20, pp.864~867
- Kim YM, "Cytopathologic observation of the lung: a case report", Korean J Pathol, 25, pp.367~375 (1991)
- Jensen OA, "Primary malignant melanoma of the lung", Scand J Respir Dis, 48, pp.127~135 (1967)
- Allen MS Jr, "Primary melanoma of the lung", Cancer, 21, pp.154~159 (1968)
- Carstens PH, "Primary malignant melanomas of the lung and adrenal", Hum Pathol, 15, pp.910~914 (1984)
- Robertson AJ, "Primary melanocarcinoma of the lower respiratory tract", Thorax, 35, pp.158~159 (1980)
- Salm R, "A primary malignant melanoma of the bronchus", J Pathol Bacteriol, 85, pp.121~126 (1963)
- Jennings TA, "Primary malignant melanoma of the lower respiratory tract", Am J Clin Pathol, 94, pp.649~655 (1990)
- Filosso PL, "Primary malignant melanoma of the bronchus intermedius", J Thorac Cardiovasc Surg, 126, pp.1215~1217 (2003)
- Duarte IG, "Primary malignant melanoma of the trachea", Ann Thorac Surg, 65, pp.559~560 (1998)
- Reed RJ 3rd, "Solitary pulmonary melanomas: two case reports", J Thorac Cardiovasc Surg, 48, pp.226~231
- Reid JD, "Melanoma of the lower respiratory tract", Cancer, 19, pp.627~631 (1966)