급성 백혈병 환아에서 유도화학치료에 의한 정맥성 뇌경색의 기능적 회복

Abstract

Incidence of cerebral venous infarction is usually lower than that of arterial infarction in elderly population. Recently, increased incidence of cerebral venous infarction as associated complications have been reported in children with acute leukemia, though advances in chemotherapy have greatly improved the prognosis. Complications of induction chemotherapy are mainly coagulation disorders, including hemorrhage, arterial, dural venous thrombosis and result in neurologic impairments, such as hemiparesis, seizure, headache, etc. Among the cerebrovascular disease, cerebral venous infarction has noticeable potency of recovery, especially, when proper therapeutic interventions are performed in early stage of course after attack of disease. We report a child with cerebral venous infarction developed due to dural venous thrombosis during chemotherapy for acute sublymphocytic leukemia whose outcome was excellent after medical and rehabilitative treatment.