항결핵 치료 중 발생한 스위트 증후군 1예
A Case of the Sweet’s Syndrome Associated with Anti tuberculous Medication
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초록
결핵 치료 중 피부 발진은 흔히 발생하는 합병증 중의 하나이다. 경계가 명확하며 통증과 발열을 동반한 발진이 발생하는 경우 일반적인 결핵 약제에 의한 발진보다는 스위트 증후군의 가능성을 생각해서 조직 검사를 통해서 확진이 필요하다. 저자는 약제 중, 리팜핀에 의한 스위트 증후군의 가능성이 있는 증례가 있어서 문헌고찰과 함께 보고하는 바이다.
Abstract
Clinical manifestations of Sweet’s syndrome typically include fever, leukocytosis, and tender, erythematous plaques with a dermal infiltration of mature neutrophils. Sweet’s syndrome is divided into three clinical categories: idiopathic, malignancy- associated, and drug-induced. No correlation between antituberculous medication and Sweet’s syndrome has previously been reported. Here, we describe a 79-year-old woman who developed an acute onset of fever and skin eruption after taking antituberculous medication. The clinical pattern and the result of skin biopsy were consistent with Sweet’s syndrome. After cessation of rifampin, the fever and skin rash disappeared. Thus, we diagnosed the patient with Sweet’s syndrome, caused by rifampin. To our knowledge, this is the first reported case of rifampin-induced Sweet’s syndrome. (Korean J Med 2011;80:S188-S193)
참고문헌 (8)
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