지속적인 메티실린 내성 황색포도알균 균혈증에 대한 Linezolid 치료 중 발생한 젖산 산증 1예
A Case of Lactic Acidosis Caused by Linezolid Treatment of Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia
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참고문헌
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초록
위 정맥류에 대한 내시경적 경화요법 이후에 위 정맥류에발생한 패혈성 혈전 정맥염이 원발병소인 지속적인 MRSA 균혈증에서 linezolid 사용 중에 발생한 젖산 산증 1예를 경험하였기에 보고하는 바이다.
Abstract
Linezolid is an antibiotic in the oxazolidinone family that works as a bacterial protein synthesis inhibitor. It is used for the treatment of Gram-positive, multidrug-resistant bacteria. Adverse effects of linezolid include bone marrow suppression, peripheral or optic neuropathy, and, less commonly, lactic acidosis. Lactic acidosis usually occurs as a result of cardiopulmonary failure or sepsis, but it is sometimes caused by drugs, such as linezolid, and treatment of such lactic acidosis involves cessation of the drug. We report a case of lactic acidosis caused by the use of linezolid for the treatment of persistent methicillin-resistant Staphylococcus aureus bacteremia, which occurred after endoscopic sclerotherapy of gastic varices. (Korean J Med 2012;82:512-515)
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