CD5- 소포림프종의 CD5+ 광범위큰B세포림프종으로 전환된 1예
Transformation of CD5-Negative Follicular Lymphoma into CD5-Positive Diffuse Large B-Cell Lymphoma: A Case Report
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of aggressive lymphomas. Approximately 10% of DLBCL cases express CD5 as a surface antigen. CD5-positive DLBCL can occur as the de novo or secondary type. De novo CD5-positive DLBCL arises without previous lymphoproliferative disease, and secondary CD5-positive DLBCL may or may not manifest as Richter syndrome. The transformation of follicular lymphoma (FL) into DLBCL occurs in approximately one-third of all cases. The transformation of CD5-negative low-grade B-cell lymphoma to CD5-positive DLBCL is extremely rare. We report the clinical features of a rare case that presented with a transformation from CD5-negative FL to CD5-positive DLBL over 11 years. This is the second such case published in the English literature. (Korean J Med 2012;83:263-267)
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of aggressive lymphomas. Approximately 10% of DLBCL cases express CD5 as a surface antigen. CD5-positive DLBCL can occur as the de novo or secondary type. De novo CD5-positive DLBCL arises without previous lymphoproliferative disease, and secondary CD5-positive DLBCL may or may not manifest as Richter syndrome. The transformation of follicular lymphoma (FL) into DLBCL occurs in approximately one-third of all cases. The transformation of CD5-negative low-grade B-cell lymphoma to CD5-positive DLBCL is extremely rare. We report the clinical features of a rare case that presented with a transformation from CD5-negative FL to CD5-positive DLBL over 11 years. This is the second such case published in the English literature. (Korean J Med 2012;83:263-267)
참고문헌 (10)
- 김진만, "WHO Classification of Malignant Lymphomas in Korea: Report of the Third Nationwide Study", The Korean Journal of Pathology, 45(3), pp.254~260 (2011), 대한병리학회
- Yuna Lee, "Two Cases of Interstitial Pneumonitis Caused by Rituximab Therapy", The Korean Journal of Internal Medicine, 21(3), pp.183~186 (2006), 대한내과학회
- Lossos IS, "Transformation of follicular lymphoma", Best Pract Res Clin Haematol, 24, pp.147~163 (2011)
- Maeshima AM, "Secondary CD5+ diffuse large B-cell lymphoma not associated with transformation of chronic lymphocytic leukemia", small lymphocytic lymphoma (Richter syndrome), 2009, pp.131, 339~346
- Yamaguchi M, "De novo CD5-positive diffuse large B-cell lymphoma: clinical characteristics and therapeutic outcome", Br J Haematol, 105, pp.1133~1139 (1999)
- Sekiguchi Y, "CD5-positive follicular lymphoma: a case report and literature review", Intern Med, 50, pp.899~904 (2011)
- Burastero SE, "Characterization of human CD5(Leu-1, OKT1)+ B lymphocytes and the antibodies theyproduce", Contrib Microbiol Immunol, 11, pp.231~262 (1989)
- Pospisil R, "CD5 is apotential selecting ligand for B-cell surface immunoglobulin: a possible role in maintenance and selective expansion of normal and malignant B cells", Leuk lymphoma, 36, pp.353~365 (2000)
- Williams CD, "High-dose therapy and autologus stem-cell support for chemosensitive transformed low-grade follicular non-Hodgkin’s lymphoma: a-case matched study from the European Bone Marrow Transformed follicular lymphoma", Eur J Haemaetol, 65, pp.17~22 (2000)
- Bernstein SH, "The incidence, natural history, biology, and treatment of transformed lymphomas", Hematology Am Soc Hematol Educ Program, pp.532~541 (2009)