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Mycobacterium massiliense 피부연조직 감염에서 완치한 1예

A Case of Skin and Soft Tissue Infection by Mycobacterium massiliense

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초록

Mycobacterium massiliense (M. massiliense) was identified recently as a species that separated from M. abscessus. Unlike M. abscessus, M. massiliense responds well to clarithromycin-based antibiotic treatment. Many cases of M. massiliense infections relatedto iatrogenic procedures have been reported. We report a case of skin and soft tissue infection by M. massiliense, which wasnot caused by medical appliances, that was treated successfully using clarithromycin monotherapy for -6 months after initial treatmentwith empirical antibiotics for 4 weeks.

Abstract

Mycobacterium massiliense (M. massiliense) was identified recently as a species that separated from M. abscessus. Unlike M. abscessus, M. massiliense responds well to clarithromycin-based antibiotic treatment. Many cases of M. massiliense infections relatedto iatrogenic procedures have been reported. We report a case of skin and soft tissue infection by M. massiliense, which wasnot caused by medical appliances, that was treated successfully using clarithromycin monotherapy for -6 months after initial treatmentwith empirical antibiotics for 4 weeks.

참고문헌 (10)

  1. Koh WJ, "Successful treatment of Mycobacterium massiliense lung disease with oral antibiotics only", Antimicrob Agents Chemother, 57, pp.1098~1100 (2013)
  2. Kyoung Hwa Choi, "A Fatal Case of Acute Respiratory Failure Caused by Mycobacterium massiliense", Tuberculosis and Respiratory Diseases, 74(2), pp.79~81 (2013), 대한결핵및호흡기학회
  3. Nakanaga K, "Multiple cases of cutaneous Mycobacterium massiliense infection in a “hot spa” in Japan", J Clin Microbiol, 49, pp.613~617 (2011)
  4. Otsuki T, "Cutaneous Mycobacterium massiliense infection: a sporadic case in Japan", J Dermatol, 39, pp.569~572 (2012)
  5. Van Ingen J, "Clinical relevance of Mycobacterium chelonae- abscessus group isolation in 95 patients", J Infect, 59, pp.324~331 (2009)
  6. Kim HY, "Outbreak of Mycobacterium massiliense infection associated with intramuscular injections", J Clin Microbiol, 45, pp.3127~3130 (2007)
  7. Zelazny AM, "Cohort study of molecular identification and typing of Mycobacterium abscessus, Mycobacterium massiliense, and Mycobacterium bolletii", J Clin Microbiol, 47, pp.1985~1995 (2009)
  8. Koh WJ, "Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus", Am J Respir Crit Care Med, 183, pp.405~410 (2011)
  9. 조아영, "Identification of Cutaneous Mycobacterium massiliense Infections Associated with Repeated Surgical Procedures", Annals of Dermatology, 22(1), pp.114~118 (2010), 대한피부과학회
  10. Daley CL, "Pulmonary disease caused by rapidly growing mycobacteria", Clin Chest Med, 23, pp.623~632 (2002)

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