Mycobacterium abscessus에 의한 피부 및 연조직 감염 1예
A Case of Skin and Soft Tissue Infection by Mycobacterium abscessus
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초록
36세 여성의 왼쪽 앞쪽 경골부에 작고 붉은 부종성 피부 농양이 발생하였다. 지속적인 소독과 항균제 치료에도 불구하고 차츰 병변부위는 악화되었다. 일반 배양검사상 혈액한천배지에서 음성소견을 보였으나, 이 후 실시된 항산성도말검사결과 붉은 색의 간균이 관찰되고 결핵분리배양검사 결과 6일째 마이코박테리아균이 자랐다. PCR-RFLP법을 이용한 동정결과 M. abscessus로 확인되었다. Clarithromycin, levofloxacin과 amikacin으로 치료를 시작하여 재발없이 호전을 보였기에 문헌고찰과 함께 보고하는 바이다.
Abstract
A 36-year-old female who initially presented with a small erythematous and swollen abscess on her left anterior tibial area was found out to have a cutaneous Mycobacterium abscessus infection. She was first treated with incision and drainage, dressing, and antibiotics. The lesion began to be aggravated and dispersed. Neither aerobic nor anaerobic bacteria was grown on blood agar plate. After a few weeks, Mycobacterium grew on Ogawa media after 6 days, and was identified as M. abscessus by PCR-restriction fragment length polymorphism. She was then treated with clarithromycin, levofloxacin, and amikacin, and the skin lesion was resolved without further recurrence.
참고문헌 (12)
- "The relationship of atypical acid-fast bacilli to human disease:A preliminary report", 44, pp.202~9 (1954)
- "Anonymous mycobacteria in pulmonary disease", 43, pp.273~90 (1959)
- "Mycobacterial diseases other than tuberculosis", 15, pp.1~12 (1992)
- "A case of skin and soft tissue infection caused by Mycobacterium abscessus", 32, pp.64~8 (2000)
- "A case of cutaneous infection due to Mycobacterium abscessus", 42, pp.512~5 (2004)
- "Five cases of Mycobacterium abscessus", 7, pp.84~9 (2004)
- "Disseminated infection with rapidly growing mycobacteria", 16, pp.463~71 (1993)
- "Cutaneous infection with Mycobacterium abscessus", 132, pp.800~4 (1995)
- "An unusual acid-fast infections of the knee with subcutaneous,abscess-like lesions of the gluteal region", 20, pp.133~69 (1953)
- "Dermatology in General Medicine", Mcgraw-Hill
- "Manual of Clinical Microbiology", pp.532~84 (2003), ASM press
- "Rapid development of resistence to clarithromycin following monotherapy for disseminated Mycobacterium chelonae infection in a heart transplant patient", 20, pp.443~4 (1995)