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호산구성 염증을 동반한 기관지 협착이 폐암으로 오인된 증례 1예

Mass-forming Eosinophilic Infiltration Involving the Central Airway: A Case Report of Endobronchial Involvement of Eosinophilic Inflammation Mimicking Bronchogenic Malignancy

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We report a very unusual case of endobronchial involvement of eosinophilic inflammation. A 58-year-old woman visited ourclinic complaining of cough. A chest computed tomography scan showed a poorly enhancing mass compressing both main bronchiin the subcarinal area. Bronchoscopy also showed stenosis of the two main bronchi with irregular mucosal thickening. A bronchoscopicendobronchial mucosal biopsy revealed eosinophilic inflammation without evidence of malignancy. The subcarinal massdisappeared after systemic steroid treatment. This is the first report of mass-forming eosinophilic infiltration involving the centralairway mimicking primary lung cancer.

Abstract

We report a very unusual case of endobronchial involvement of eosinophilic inflammation. A 58-year-old woman visited ourclinic complaining of cough. A chest computed tomography scan showed a poorly enhancing mass compressing both main bronchiin the subcarinal area. Bronchoscopy also showed stenosis of the two main bronchi with irregular mucosal thickening. A bronchoscopicendobronchial mucosal biopsy revealed eosinophilic inflammation without evidence of malignancy. The subcarinal massdisappeared after systemic steroid treatment. This is the first report of mass-forming eosinophilic infiltration involving the centralairway mimicking primary lung cancer.

참고문헌 (6)

  1. Jeong YJ, "Eosinophilic lung diseases: a clinical, radiologic, and pathologic overview", Radiographics, 27, pp.617~637 (2007)
  2. Matsushima H, "Multiple tracheobronchial mucosal lesions in two cases of Churg- Strauss syndrome", Respirology, 11, pp.109~112 (2006)
  3. Hara J, "Chronic eosinophilic pneumonia with endobronchial involvement", J Bronchology Interv Pulmonol, 18, pp.285~287 (2011)
  4. Niimi A, "Inflammatory bronchial polyps associated with asthma: resolution with inhaled corticosteroid", Eur Respir J, 8, pp.1237~1239 (1995)
  5. O’Donnell AE, "Endobronchial eosinophilic granuloma: a rare cause of total lung atelectasis", Am Rev Respir Dis, 136, pp.1478~1480 (1987)
  6. Loukides S, "Eosinophilic granuloma of the lung presenting as an endobronchial mass", Monaldi Arch Chest Dis, 55, pp.208~209 (2000)

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