16번 염색체 역위를 가진 급성 골수성 백혈병의 복막 골수성 육종 1예
Myeloid Sarcoma of Peritoneum in Acute Myeloid Leukemia Patient with Inversion of Chromosome 16
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초록
골수성 육종(Myeloid sarcoma)은 골수 외를 침범하는 질환으로 급성 골수성 백혈병에서 발생하는 드문 종양이다. inv (16) 염색체 이상을 가진 골수성 육종은 대부분 복강 내에서, 특히 소화관을 침범하는 종괴의 형태로 나타나지만 본 증례에서는 복막의 침윤 및 복수의 형태로 나타나 1예가 있어 보고하는 바이다.
Abstract
Myeloid sarcoma is an extramedullary myeloid neoplasm that usually involves the skin, soft tissues, and lymph nodes. Myeloid sarcoma is found in 2.5-9.1% of acute myeloid leukemia patients, usually those with t (8;21), while inv (16) is rarely associated with myeloid sarcoma. Consequently, little is known of the characteristics and incidence of inv (16) in myeloid sarcoma. Myeloid sarcoma in acute myeloid leukemia patients with inv (16) is most often found in the abdominal lesions; the intestinal tract is involved most commonly, in the form of a mass. Here, we report an unusual myeloid sarcoma presenting as peritoneal carcinomatosis in acute myeloid leukemia with inv (16) that appeared to be ascites.
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