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유미흉으로 발현된 말초성 T세포 림프종 1예

Peripheral T-cell Lymphoma Presenting with Chylothorax

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초록

말초형 T세포 림프종은, 림프절외 증상이 비특이적으로나타날 경우 질병이 진행하기 전까지 진단이 어려울 수 있다. 본 증례는 T세포 림프종에 의한 림프절 종대의 빠른 진행과 함께 드문 합병증인 유미흉으로 발현한 환자이며 비특정 말초 T세포 림프종으로 확진된 1예로 호흡곤란을 유발하는 유미흉을 적절히 조절하여, 항암화학요법을 속히 시행하고 부분반응을 얻을 수 있었던 증례이다.

Abstract

A 72-year-old male presented with respiratory discomfort. A simple chest X-ray and abdominal computed tomography showed pleural effusion and multiple lymph node enlargement. The pleural effusion was determined by thoracentesis to be chylothorax. An inguinal lymph node biopsy showed peripheral T-cell lymphoma. Following three cycles of cyclophospamide, hydroxyl doxorubicin, vincristine, prednisolone (CHOP) chemotherapy, a partial response was observed. Chylothorax is an extremely rare complication of T-cell lymphoma. We present a case of peripheral T-cell lymphoma presenting with chylothorax. We suggest that clinicians should consider chylothorax when examining patients with lymphoma who present with atypical pleural effusion.

참고문헌 (9)

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  2. McGrath EE, "Chylothorax: aetiology, diagnosis and therapeutic options", Respir Med, 104, pp.1~8 (2010)
  3. Iqbal MH, "Chylothorax due to angioimmunoblastic T-cell lymphoma", Intern Med J, 39, pp.67~68 (2009)
  4. Jaffe ES, "Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls", Mod Pathol, 26(Suppl 1), pp.S71~S87 (2013)
  5. Tang T, "Peripheral T-cell lymphoma:review and updates of current management strategies", Adv Hematol, 2010, pp.624040~ (2010)
  6. Doerr CH, "Etiology of chylothorax in 203 patients", Mayo Clin Proc, 80, pp.867~870 (2005)
  7. Maldonado F, "Pleural fluid characteristics of chylothorax", Mayo Clin Proc, 84, pp.129~133 (2009)
  8. 고옥배, "Clinicopathologic Characteristics of T-cell Non-Hodgkin’s Lymphoma: A Single Institution Experience", The Korean Journal of Internal Medicine, 24(2), pp.128~134 (2009), 대한내과학회
  9. Sang Hyoung Park, "ESHAP Salvage Therapy for Refractory and Relapsed Non-Hodgkin’s Lymphoma: A Single Center Experience", The Korean Journal of Internal Medicine, 21(3), pp.159~164 (2006), 대한내과학회

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