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Current Stem Cell Therapy for Osteoarthritis
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Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician’s office. There is a growing need, therefore, for physicians to pay attention to this common orthopedic condition. Cartilage degeneration, arthritic pain, and joint dysfunction are major manifestations of osteoarthritis, and degenerated cartilage is difficult to repair with conventional treatment modalities. Scientists and physicians have developed various therapeutic strategies, including the use of stem cells. Here, we discuss previous and current progress in cartilage regenerative therapy against osteoarthritis.
Abstract
Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician’s office. There is a growing need, therefore, for physicians to pay attention to this common orthopedic condition. Cartilage degeneration, arthritic pain, and joint dysfunction are major manifestations of osteoarthritis, and degenerated cartilage is difficult to repair with conventional treatment modalities. Scientists and physicians have developed various therapeutic strategies, including the use of stem cells. Here, we discuss previous and current progress in cartilage regenerative therapy against osteoarthritis.
참고문헌 (66)
- Li MH, "Regenerative approaches for cartilage repair in the treatment of osteoarthritis", Osteoarthritis Cartilage, 25, pp.1577~1587 (2017)
- 이재정, "Results of Microfracture in the Osteoarthritic Knee with Focal Full-Thickness Articular Cartilage Defects and Concomitant Medial Meniscal Tears", Knee Surgery and Related Research, 25(2), pp.71~76 (2013), 대한슬관절학회
- Mithoefer K, "The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study", J Bone Joint Surg Am, 87, pp.1911~1920 (2005)
- Pässler HH, "Microfracture for treatment of cartilage detects", Zentralbl Chir, 125, pp.500~504 (2000)
- Steadman JR, "Outcomes of microfracture for traumatic chondral defects of the knee : average 11-year follow-up", Arthroscopy, 19, pp.477~484 (2003)
- Bae DK, "Cartilage healing after microfracture in osteoarthritic knees", Arthroscopy, 22, pp.367~374 (2006)
- Steadman JR, "Microfracture : its history and experience of the developing surgeon", Cartilage, 1, pp.78~86 (2010)
- Peterson L, "Two-to 9-year outcome after autologous chondrocyte transplantation of the knee", Clin Orthop Relat Res, pp.212~234 (2000)
- Vasara AI, "Indentation stiffness of repair tissue after autologous chondrocyte transplantation", Clin Orthop Relat Res, pp.233~242 (2005)
- Peterson L, "Autologous chondrocyte implantation : a long-term follow-up", Am J Sports Med, 38, pp.1117~1124 (2010)
- Minas T, "The John Insall Award : a minimum 10-year outcome study of autologous chondrocyte implantation", Clin Orthop Relat Res, 472, pp.41~51 (2014)
- Behery OA, "Factors influencing the outcome of autologous chondrocyte implantation : a systematic review", J Knee Surg, 26, pp.203~211 (2013)
- Saris DB, "Treatment of symptomatic cartilage defects of the knee : characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture", Am J Sports Med, 37(Suppl 1), pp.10S~19S (2009)
- Saris DB, "Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture", Am J Sports Med, 36, pp.235~246 (2008)
- Enea D, "Matrix-induced autologous chondrocyte implantation(MACI)in the knee", Knee Surg Sports Traumatol Arthrosc, 20, pp.862~869 (2012)
- Gigante A, "Engineered articular cartilage : influence of the scaffold on cell phenotype and proliferation", J Mater Sci Mater Med, 14, pp.713~716 (2003)
- Marcacci M, "Articular cartilage engineering with Hyalograft C: 3-year clinical results", Clin Orthop Relat Res, pp.96~105 (2005)
- Gooding CR, "A prospective, randomised study comparing two techniques of autologous chondrocyte implantation for osteochondral defects in the knee : periosteum covered versus type I", III collagen covered, 2006, pp.13, 203~210
- Tsumaki N, "iPS cell technologies and cartilage regeneration", Bone, 70, pp.48~54 (2015)
- Roberts S, "Immunohistochemical study of collagen types I and II and procollagen IIA in human cartilage repair tissue following autologous chondrocyte implantation", Knee, 16, pp.398~404 (2009)
- Cancedda R, "Tissue engineering and cell therapy of cartilage and bone", Matrix Biol, 22, pp.81~91 (2003)
- Caplan AI, "Principles of tissue engineered regeneration of skeletal tissues", Clin Orthop Relat Res, (Suppl 367), pp.S12~S16 (1999)
- Liu H, "Thermosensitive injectable in-situ forming carboxymethyl chitin hydrogel for three-dimensional cell culture", Acta Biomater, 35, pp.228~237 (2016)
- Izadifar Z, "Strategic design and fabrication of engineered scaffolds for articular cartilage repair", J Funct Biomater, 3, pp.799~838 (2012)
- Yoon JJ, "Surface immobilization of galactose onto aliphatic biodegradable polymers for hepatocyte culture", Biotechnol Bioeng, 78, pp.1~10 (2002)
- Park GE, "Accelerated chondrocyte functions on NaOH-treated PLGA scaffolds", Biomaterials, 26, pp.3075~3082 (2005)
- Morille M, "PLGA-based microcarriers induce mesenchymal stem cell chondrogenesis and stimulate cartilage repair in osteoarthritis", Biomaterials, 88, pp.60~69 (2016)
- Erickson GR, "Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo", Biochem Biophys Res Commun, 290, pp.763~769 (2002)
- Zhang Z, "Hyaline cartilage engineered by chondrocytes in pellet culture : histological, immunohistochemical and ultrastructural analysis in comparison with cartilage explants", J Anat, 205, pp.229~237 (2004)
- Schnabel M, "Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture", Osteoarthritis Cartilage, 10, pp.62~70 (2002)
- Johnstone B, "In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells", Exp Cell Res, 238, pp.265~272 (1998)
- Ke H, "Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells", Differentiation, 77, pp.256~262 (2009)
- Mueller MB, "Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells", Arthritis Rheum, 58, pp.1377~1388 (2008)
- Murdoch AD, "Chondrogenic differentiation of human bone marrow stem cells in transwell cultures : generation of scaffold-free cartilage", Stem Cells, 25, pp.2786~2796 (2007)
- Friedenstein AJ, "Precursor cells of mechanocytes", Int Rev Cytol, 47, pp.327~359 (1976)
- Solchaga LA, "Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells : tips and tricks", Methods Mol Biol, 698, pp.253~278 (2011)
- Nam Y, "Chondrogenic pellet formation from cord blood-derived induced pluripotent stem cells", J Vis Exp, 19 (2017)
- Nam Y, "Cord blood cell-derived iPSCs as a new candidate for chondrogenic differentiation and cartilage regeneration", Stem Cell Res Ther, 8, pp.16~ (2017)
- Nam Y, "Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis", PLoS One, 13, pp.e0198740~ (2018)
- Locke M, "Human adipose-derived stem cells : isolation, characterization and applications in surgery", ANZ J Surg, 79, pp.235~244 (2009)
- Solchaga LA, "Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone-marrow-derived mesenchymal stem cells", Tissue Eng Part A, 16, pp.1009~1019 (2010)
- Nejadnik H, "Improved approach for chondrogenic differentiation of human induced pluripotent stem cells", Stem Cell Rev, 11, pp.242~253 (2015)
- Mitchell JB, "Immunophenotype of human adipose-derived cells : temporal changes in stromal-associated and stem cell-associated markers", Stem Cells, 24, pp.376~385 (2006)
- Zuk PA, "Multilineage cells from human adipose tissue : implications for cell-based therapies", Tissue Eng, 7, pp.211~228 (2001)
- Aust L, "Yield of human adipose-derived adult stem cells from liposuction aspirates", Cytotherapy, 6, pp.7~14 (2004)
- Kern S, "Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue", Stem Cells, 24, pp.1294~1301 (2006)
- Sekiya I, "Expansion of human adult stem cells from bone marrow stroma : conditions that maximize the yields of early progenitors and evaluate their quality", Stem Cells, 20, pp.530~541 (2002)
- Gimble J, "Adipose-derived adult stem cells : isolation, characterization, and differentiation potential", Cytotherapy, 5, pp.362~369 (2003)
- Wickham MQ, "Multipotent stromal cells derived from the infrapatellar fat pad of the knee", Clin Orthop Relat Res, pp.196~212 (2003)
- Black LL, "Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs", Vet Ther, 9, pp.192~200 (2008)
- van Buul GM, "Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis", J Orthop Res, 32, pp.1167~1174 (2014)
- Freitag J, "Mesenchymal stem cell therapy in the treatment of osteoarthritis : reparative pathways, safety and efficacy-a review", BMC Musculoskelet Disord, 17, pp.230~ (2016)
- Vangsness CT Jr, "Adult human mesenchymal stem cells delivered via intra-articular injection to the knee following partial medial meniscectomy : a randomized, double-blind, controlled study", J Bone Joint Surg Am, 96, pp.90~98 (2014)
- Lee J, "Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis", Arthritis Res Ther, 16, pp.R41~ (2014)
- Rim YA, "Generation of induced-pluripotent stem cells using fibroblast-like synoviocytes isolated from joints of rheumatoid arthritis patients", J Vis Exp (2016)
- Rim YA, "Induced pluripotent stem cell generation from blood cells using sendai virus and centrifugation", J Vis Exp, (118), pp.54650~ (2016)
- Kim Y, "The generation of human induced pluripotent stem cells from blood cells : an efficient protocol using serial plating of reprogrammed cells by centrifugation", Stem Cells Int, 2016, pp.1329459~ (2016)
- Kim J, "Recapitulation of methotrexate hepatotoxicity with induced pluripotent stem cell-derived hepatocytes from patients with rheumatoid arthritis", Stem Cell Res Ther, 9, pp.357~ (2018)
- Kim Y, "Establishment of a complex skin structure via layered co-culture of keratinocytes and fibroblasts derived from induced pluripotent stem cells", Stem Cell Res Ther, 9, pp.217~ (2018)
- Yan X, "iPS cells reprogrammed from human mesenchymal-like stem", progenitor cells of dental tissue origin, 2010, pp.19, 469~480
- Karow M, "Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA", Stem Cells, 29, pp.1696~1704 (2011)
- Rim YA, "Repair potential of nonsurgically delivered induced pluripotent stem cell-derived chondrocytes in a rat osteochondral defect model", J Tissue Eng Regen Med, 12, pp.1843~1855 (2018)
- Ko JY, "In vitro chondrogenesis and in vivo repair of osteochondral defect with human induced pluripotent stem cells", Biomaterials, 35, pp.3571~3581 (2014)
- Zhu Y, "Repair of cartilage defects in osteoarthritis rats with induced pluripotent stem cell derived chondrocytes", BMC Biotechnol, 16, pp.78~ (2016)
- Yamashita A, "Generation of scaffoldless hyaline cartilaginous tissue from human iPSCs", Stem Cell Reports, 4, pp.404~418 (2015)
- Nam Y, "Current therapeutic strategies for stem cell-based cartilage regeneration", Stem Cells Int, 2018, pp.8490489~ (2018)
