본문 바로가기
KERD
논문KCI 등재

Association of Visceral Fat and Risk Factors for Metabolic Syndrome in Children and Adolescents

정주혜|한지환|오민진|염근상|노준승|Jeong-Hyeon Kwon|장한윤
연세대학교의과대학 (Yonsei University College of Medicine)|2011.01|Yonsei Medical Journal|제52권 제1호|pp. 39-44

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

Childrenadolescentsmetabolic syndromevisceral fat
주제분류의학일반

초록

Purpose: Visceral fat (VF) is closely associated with many metabolic risk factors and is also known to be a strong predictive factor for severe metabolic complications in adults. But there are only a few studies concerning the association of VF and risk factors for metabolic syndrome (MS) in children and adolescents. In our study, we emphasized the association of VF [measured by VF computed tomography (VFCT)] and risk factors for metabolic syndrome in children and adolescents. Materials and Methods: The subjects were outpatients aged 6 to 18 years who underwent VFCT in the family medicine of The Catholic University of Korea from January 2005 to August 2009. There were 82 patients in total (42 children, 40 adolescents). Height, weight, blood pressure (BP), blood tests, body composition analysis and VF were measured. The three groups were also classified by metabolic score. Results: In children,only high density lipoprotein cholesterol (HDL-C) showed a statistically significant difference, while in adolescents, triglyceride, HDL-C, BP, body mass index (BMI), waist circumference (WC) and VFA showed statistically significant differences. In terms of VFA, fasting glucose, BP, BMI, basal metabolic rate (BMR) and WC showed statistically significant differences. BMI showed a statistically significant difference in terms of BP, BMR, WC, VFA and HDL-C. Conclusion: There is a need to acknowledge the statistically significant associations of VF and risk factors for MS in children and adolescents. Screening tests for BP, cholesterol, fasting glucose and WC should be given in clinics for children and adolescents so that MS can be detected and its risk factors treated early.

Abstract

Purpose: Visceral fat (VF) is closely associated with many metabolic risk factors and is also known to be a strong predictive factor for severe metabolic complications in adults. But there are only a few studies concerning the association of VF and risk factors for metabolic syndrome (MS) in children and adolescents. In our study, we emphasized the association of VF [measured by VF computed tomography (VFCT)] and risk factors for metabolic syndrome in children and adolescents. Materials and Methods: The subjects were outpatients aged 6 to 18 years who underwent VFCT in the family medicine of The Catholic University of Korea from January 2005 to August 2009. There were 82 patients in total (42 children, 40 adolescents). Height, weight, blood pressure (BP), blood tests, body composition analysis and VF were measured. The three groups were also classified by metabolic score. Results: In children,only high density lipoprotein cholesterol (HDL-C) showed a statistically significant difference, while in adolescents, triglyceride, HDL-C, BP, body mass index (BMI), waist circumference (WC) and VFA showed statistically significant differences. In terms of VFA, fasting glucose, BP, BMI, basal metabolic rate (BMR) and WC showed statistically significant differences. BMI showed a statistically significant difference in terms of BP, BMR, WC, VFA and HDL-C. Conclusion: There is a need to acknowledge the statistically significant associations of VF and risk factors for MS in children and adolescents. Screening tests for BP, cholesterol, fasting glucose and WC should be given in clinics for children and adolescents so that MS can be detected and its risk factors treated early.

참고문헌 (28)

  1. Lobstein T, "Prevalence of overweight among children in Europe", Obes Rev, 4, pp.195~200 (2003)
  2. Popkin BM, "Is there a lag globally in overweight trends for children compared with adults", Obesity (Silver Spring), 14, pp.1846~1853 (2006)
  3. 박영신, "23년간 서울 지역 초·중·고등학생의 비만 추이", Korean Journal of Pediatrics, 47(3), pp.247~257 (2004), 대한소아과학회
  4. Epstein LH, "Childhood obesity", Pediatr Clin North Am, 32, pp.363~379 (1985)
  5. Dietz WH Jr, "Childhood obesity: susceptibility, cause, and management", J Pediatr, 103, pp.676~686 (1983)
  6. Bao W, "Longitudinal changes in cardiovascular risk from childhood to young adulthood in offspring of parents with coronary artery disease: the Bogalusa Heart Study", JAMA, 278, pp.1749~1754 (1997)
  7. Grundy SM, "Hypertriglyceridemia, insulin resistance, and the metabolic syndrome", Am J Cardiol, 83, pp.25F~9F (1999)
  8. 홍영미, "소아 및 청소년의 대사증후군", Korean Journal of Pediatrics, 52(7), pp.737~744 (2009), 대한소아과학회
  9. 서민정, "한국 소아와 청소년에서 대사증후군의 유병률", Korean Journal of Family Medicine, 27(10), pp.798~806 (2006), 대한가정의학회
  10. 차봉수, "대사 증후군에서 관동맥 질환 발생의 기전 및 예방과 치료", Korean Circulation Journal, 33(8), pp.645~652 (2003), 대한심장학회
  11. Zimmet P, "The metabolic syndrome in children and adolescents", Lancet, 369, pp.2059~2061 (2007)
  12. Weiss R, "Obesity and the metabolic syndrome in children and adolescents", N Engl J Med, 350, pp.2362~2374 (2004)
  13. Guo SS, "The predictive value of childhood body mass index values for overweight at age 35 y", Am J Clin Nutr, 59, pp.810~819 (1994)
  14. Cruz ML, "The metabolic syndrome in overweight Hispanic youth and the role of insulin sensitivity", J Clin Endocrinol Metab, 89, pp.108~113 (2004)
  15. Druet C, "Insulin resistance and the metabolic syndrome in obese French children", Clin Endocrinol (Oxf), 64, pp.672~678 (2006)
  16. Pouliot MC, "Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels", Diabetes, 41, pp.826~834 (1992)
  17. Pouliot MC, "Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women", Am J Cardiol, 73, pp.460~468 (1994)
  18. Cook S, "Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994", Arch Pediatr Adolesc Med, 157, pp.821~827 (2003)
  19. 염혜원, "소아 비만에서 대사증후군의 고찰", Pediatric Gastroenterology, Hepatology & Nutrition, 7(2), pp.228~238 (2004), 대한소아소화기영양학회
  20. 조기영, "소아청소년 비만에서 생활습관과 대사증후군의 연관성", Pediatric Gastroenterology, Hepatology & Nutrition, 11(2), pp.150~159 (2008), 대한소아소화기영양학회
  21. 조영규, "한국 소아 청소년의 대사증후군 유병률 - IDF 소아 청소년 대사증후군 진단기준에 의하여", Korean Journal of Family Medicine, 30(4), pp.261~268 (2009), 대한가정의학회
  22. 장진하, "소아비만증에서 대사 증후군의 유병률", Korean Journal of Pediatrics, 47(11), pp.1149~1156 (2004), 대한소아과학회
  23. Stark O, "Longitudinal study of obesity in the National Survey of Health and Development", Br Med J (Clin Res Ed), 283, pp.13~17 (1981)
  24. Weiss R, "Obesity and the metabolic syndrome in children and adolescents", N Engl J Med, 350, pp.2362~2374 (2004)
  25. Kim JA, "Association of abdominal fat distribution and cardiometabolic risk factors among obese Korean adolescents", DIABETES & METABOLISM, 34(2), pp.126~130 (2008), MASSON EDITEUR
  26. Druet C, "Independent effect of visceral adipose tissue on metabolic syndrome in obese adolescents", Horm Res, 70, pp.22~28 (2008)
  27. Park HS, "Clustering of cardiovascular risk factors and cornary artery disease", J Korean Acad Fam Med, 19, pp.881~893 (1998)
  28. Cho H, "Visceral Fat Accumulation in Coronary Artery Disease", Korean Circ J, 28, pp.740~748 (1998)

관련 논문AI추천

Cut-Off Values of Visceral Fat Area and Waist-to-Height Ratio: Diagnostic Criteria for Obesity-Related Disorders in Korean Children and Adolescents박혜순, 염근상, 이강건연세대학교의과대학 · Yonsei Medical Journal2012 · 제53권 제1호한국 소아 청소년 남아에서 복부 지방 분포 측정의 임상적 의의김경모, 명준표, 박혜순, 오석희, 이연주대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2010 · 제13권 제2호Waist- to-Height Ratio as an Index for Cardiometabolic Risk in Adolescents: Results from the 1998−2008 KNHANES박미정, 유은경, 정인혁, Sangshin Park연세대학교의과대학 · Yonsei Medical Journal2016 · 제57권 제3호17∼19세의 청소년에서 대사증후군 선별검사로서 허리둘레-신장비의 유용성김아름, 홍창호대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2011 · 제14권 제4호The Prevalence of the Metabolic Syndrome in Korean Children and Adolescents: Comparisons of the Criteria of Cook et al., Cruz and Goran, and Ferranti et al.서수진, 이승욱, 이효영연세대학교의과대학 · Yonsei Medical Journal2008 · 제49권 제4호Waist-height ratio and body mass index as indicators of obesity and cardiometabolic risk in Korean children and adolescentsAn Sejin, Hwang Jin Soon, Kim Min Yeong, Lee Hae Sang, Shim Young Suk대한소아내분비학회 · Annals of Pediatric Endocrinology & Metabolism2024 · 제29권 제3호

이 간행물의 다른 논문 (18건)

Association of the Adiponectin Gene Variations with Risk of Ischemic Stroke in a Korean Population박영규, 김승호, My-Young Cheong, 김영주, 방옥선, 차민호pp. 20-25Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy이재웅, 박성훈, 장영숙, 김창환, 김동규, 민광선, 정기석, 김철홍, 장승훈, 황용일pp. 51-58Validation of the Simplified Acute Physiology Score 3 Scoring System in a Korean Intensive Care UnitSo Yeon Lim, 권오정, 함초롬, 박소영, 김수현, 전경만, 엄상원, 정만표, Gee Young Suh, 박맹렬, 김호중pp. 59-64Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats최서희, 구수현, 신종범, 정유진, Ga Won Jeon, 성동경, 장윤실, Won Soon Parkpp. 65-73The Role of 18^F-FDG PET/CT in the Evaluation of Gastric Cancer Recurrence after Curative Gastrectomy전태주, 박필원, 강민경, 권창일, Ji Eun Lee, 안대호, 고광현, 황성규, 홍성표, 임규성pp. 81-88
원문 보기