싸이크로스포린을 이용한 고분자막 전위차 전극

Abstract

The main component governing selectivity in ion-selective electrodes and optodes is the ionophore. For this reason, a member of natural products that possess selective ion-binding properties have long been sought after. By applying this principle, the performance of cyclosporin used as neutral carriers for calcium selective polymeric membrane electrode was investigated. The calcium ion-selective electrode based on cyclosporin gave a good Nernstian response of 26.6 mV per decade for calcium ion in the activity range 1×10−6 M to 1×10−2 M. The optimized calcium ion-selective electrode displayed very comparable selectivity for Ca2+ ion against alkali and alkaline earth metal ions, Na+, and Mg2+ in particular.