유방암치료 후 흉골에 발생한 방사선속발성 골육종 1예
A case of radiation-induced sternal osteosarcoma after treatment of breast cancer
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방사선 조사 부위에 이차적으로 발생하는 골육종은 그 빈도는 매우 낮으나 원발성골육종에 비해 나쁜 예후를 가지는 것으로 되어 있다. 저자들은 유방암에 대한 수술시행 후 보조 항암화학요법과 보조 방사선요법을 시행받은 여성에서 방사선에 의한 이차성 골육종의 발생을 경험하였다. 53세 여자 환자는 방사선 조사 6년 후 전흉부의 동통을 동반한 종괴를 주소로 내원하였고, 조직 검사상 흉골의 골육종으로 진단되었다. 진단 시 전이 부위가 없었으나 두 달 후 간전이가 발견되는 매우 공격적인 양상을 보였다.
Abstract
Radiation-induced osteosarcoma is a very rare complication of radiation therapy, with a poor prognosis. We experienced a case of radiation-induced osteosarcoma of the sternum, in a patient who had had breast cancer treated with surgery, adjuvant chemotherapy, and adjuvant radiation therapy 6 years earlier. A 53-year-old woman complained of a painful anterior chest wall mass. The mass was diagnosed as osteosarcoma on biopsy. The radiation-induced osteosarcoma had an aggressive nature.
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