방사선치료 후 발생한 접형골 및 사대의 연골육종 1예
A Case of Postradiation Chondrosarcoma of the Sphenoid and Clivus
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Radiation-induced chondrosarcoma is very rarely encountered in the head and neck malignancy. Rate of chondrosarcoma is 9% of all radiation-induced bone sarcomas. Postradiation chondrosarcoma, like their spontaneous counterparts, are relatively radioresistant tumors, and prompt radical surgery has been the mainstay of therapy. However, not all postradiation chondrosarcoma are amenable to radical surgery. The location of the tumor is one of the most important factors in choosing a therapeutic modality and significantly influences the survival rate. The authors experienced a case of chondrosarcoma of the sphenoid sinus and clivus accompanying sixth and ninth cranial nerve palsies after radiation therapy of nasopharyngeal carcinoma.
Abstract
Radiation-induced chondrosarcoma is very rarely encountered in the head and neck malignancy. Rate of chondrosarcoma is 9% of all radiation-induced bone sarcomas. Postradiation chondrosarcoma, like their spontaneous counterparts, are relatively radioresistant tumors, and prompt radical surgery has been the mainstay of therapy. However, not all postradiation chondrosarcoma are amenable to radical surgery. The location of the tumor is one of the most important factors in choosing a therapeutic modality and significantly influences the survival rate. The authors experienced a case of chondrosarcoma of the sphenoid sinus and clivus accompanying sixth and ninth cranial nerve palsies after radiation therapy of nasopharyngeal carcinoma.
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