당뇨병 임부의 신생아에서 발견된미단부퇴행증후군 1예
A Case of Caudal Regression Syndrome in the Newbornof the Diabetic Mother
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초록
미단부퇴행증후군은 천미추와 요천미추의 무발생을 특징으로 복합적인 골반과 하지의 근골격계 기형을 동반하는 질환이다. 이 질환은 당뇨병 임신에서 발생하는 매우 드문 질환이며, 기형에 대한 병인은 정확히 알려져 있지 않으나 고혈당이 중요한 역할을 하는 것으로 생각되고 있다. 그리하여 임신전과 임신초기의 철저한 당조절이 이 질환의 발생을 줄일 수 있을 것으로 추측할 수 있다.
Abstract
The Caudal regression syndrome is characterized by sacrococcygeal or lumbosacrococcygeal agenesis, of variable extent, most often accompanied by multiple musculoskeletal abnormalities of the pelvis and legs. It is rare fetal complication of diabetic pregnancy. Although the exact teratogenic mechanism is not known, hyperglycemia appears to play a crucial role as a teratogen. Strict control of diabetes preconceptually and in early pregnancy is presumed to reduce the risk of occurrence. We report a case of caudal regression syndrome detected by pelvic radiography and MRI in the newborn of the diabetic mother.
참고문헌 (11)
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