자궁 질에 발생한 위장관기질종양 1예
GASTROINTESTINAL STROMAL TUMOR IN VAGINA: A CASE REPORT
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초록
위장관기질종양은 주로 위장관 벽에 발생하는 종양으로 위장관외에 발생한 예는 위장관기질종양의 약 5%에 불과하며 특히 질에 보고된 예는 매우 희귀하다. 49세 여자환자가 수 주간 촉지된 질종양을 주소로 내원하였다. 종괴는 질 외후벽에 위치하고 있었으며 크기는3.0 × 3.0 cm이었다. 조직학적으로 고밀도의 방추형세포로 구성되어 있었으며 유사 분열수는 50군데의 고배율(10 HPF) 시야당 10개 이상이었다. 이 종양세포는 c-kit (CD117)과 CD34에 양성이었다. 치료는 수술이 제일 좋은 방법으로 되어 있으며 장기간 추척 관찰을 요한다. 저자들은 드물지만 질의 기질 종양 중 감별을 요하는 위장관기질종양을 경험하여 이를 문헌 고찰과 함께 보고하는 바이다.
Abstract
Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that usually arises within the gastrointestinal tract. However extragastrointestinal stromal tumor (EGIST) is a rare tumor (5%), especially few cases of EGIST arising in vagina have currently been reported in the literature. We have experienced a case of vaginal GIST. A 49-year-old female presented with vaginal mass for three weeks. The mass was located posterolateral vagina near to introitus and 3.0 × 2.5 cm in size. Histological examination showed hypercelluar spindle cell proliferation and more than 10 mitoses per 50 high power fi elds. They were positive for c-kit (CD 117) and CD34. Surgery is the most effective treatment and long term follow up is warranted.
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