A longitudinal study of three-dimensional ultrasonographic assessment of the placenta in uncomplicated pregnancies
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Objective The purpose of our study was to investigate the relationship between birth weight and 3-dimensional (3D) power Doppler histogram of the placenta in the first- and second-trimester of uncomplicated pregnancies. Methods In this longitudinal study, 3D power Doppler ultrasound was performed in 54 non-smoking women with uncomplicated pregnancies at 10 to 13 weeks of gestation and subsequently at 19 to 22 weeks. A correlation and regression analysis was performed for placental volume (PV) and vascular indices versus clinical and sonographic variables. Results All vascular indices of the second-trimester were significantly greater than values of the first-trimester. Placental vascular indices showed an incremental tendency with birth weight, which was only statistically significant when the flow index (FI) of the first-trimester was considered (P=0.02). The PV of both the first- and second-trimester has a negative correlation with FI of the second-trimester. Conclusion Our findings suggest that FI of the placenta in the first-trimester significantly affects growth of the fetus and placenta, likely reflecting the degree of placental vascularization during the first-trimester.
Abstract
Objective The purpose of our study was to investigate the relationship between birth weight and 3-dimensional (3D) power Doppler histogram of the placenta in the first- and second-trimester of uncomplicated pregnancies. Methods In this longitudinal study, 3D power Doppler ultrasound was performed in 54 non-smoking women with uncomplicated pregnancies at 10 to 13 weeks of gestation and subsequently at 19 to 22 weeks. A correlation and regression analysis was performed for placental volume (PV) and vascular indices versus clinical and sonographic variables. Results All vascular indices of the second-trimester were significantly greater than values of the first-trimester. Placental vascular indices showed an incremental tendency with birth weight, which was only statistically significant when the flow index (FI) of the first-trimester was considered (P=0.02). The PV of both the first- and second-trimester has a negative correlation with FI of the second-trimester. Conclusion Our findings suggest that FI of the placenta in the first-trimester significantly affects growth of the fetus and placenta, likely reflecting the degree of placental vascularization during the first-trimester.
참고문헌 (16)
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