유방의 유두상 종양에 대한 맘모톰 절제술의 임상적 경험
The clinical experience of ultrasound-guided vacuum-assisted biopsy device (Mammotome) resection for the papillary neoplasm of breast
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목적유방의 유두상 종양은 핵생검으로 양성 종양과 악성 종양의 감별이 어려운 경우가 많아, 병변의 완전 절제를 통한 조직학적 검사가 필요한 것으로 알려져 있다. 우리는 맘모톰 유방종괴절제술을 통해 유두상 종양의 정확한 진단에 대한 임상적인 경험을 소개하고자 한다. 연구방법2007년 10월부터 2011년 10월까지 화명일신기독병원 유방클리닉에서 초음파와 핵생검을 시행한 후 유두상 종양으로 진단되어 맘모톰 유방종괴절제술을 시행한 25명을 대상으로 하여 이들에 대한 조직학적 소견을 바탕으로 후향적 연구를 시행하였다. 결과핵생검상 유두상 종양으로 진단된 25예에서 맘모톰 유방종괴 절제술 후 관내 유두종으로 진단된 경우가 17예(68.0%)이었고, 풍부한 상피증식을 동반한 경우가 3예(12.0%)에서 관찰되었으며 비정형 상피증식을 동반한 경우도 4예(16.0%)에서 관찰되었다. 1예에서는 관상피내암으로 진단되었다. 결론유두상 종양은 과거에는 외과적 절제를 통하여서만 병변의 정확한 평가와 동반된 악성 병변의 여부를 확인할 수 있다고 하였다. 그러나 본 연구에는 8게이지 맘모톰을 사용하여 유두상 종양을 절제한 경우에도 양성 병변과 악성 병변에 대한 정확한 진단이 가능함을 알 수 있었다.
Abstract
Objective Papillary tumor is known to be evaluated the histology through complete resection because of difficulty to distinguish between benign tumor and malignant tumor through core needle biopsy. We introduced clinical experience for better diagnosis of papillary tumor through ultrasound-guided vacuum-assisted resection (Mammotome). Methods We carried out core needle biopsy and Mammotome for 25 patients diagnosed to papillary tumor and found out the pathologic results. Results We diagnosed 17 cases (68.0%) of intraductal papilloma, 3 cases (12.0%) of intraductal papilloma with florid epithelial hyperplasia, 4 cases (16.0%) of atypical papilloma, and 1 case of ductal carcinoma in situ. Conclusion These results suggest Mammotome is useful procedure for providing more correct pathologic findings through complete resection for papillary tumors.
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