본문 바로가기
KERD
논문KCI 등재

아토피 피부염 임상 연구의 최근 3년간 동

The Trend in Clinical Study on Atopic Dermatitis Over the Last 3 YearsCHOI In-Hwa

2

조회

0

다운로드

2

인용

0

참고문헌

주제분류한의학

초록

Abstract

Objective : To observe the trend in clinical study on atopic dermatitis(AD) over the last 3 years in order to develop a study methodology of AD in Oriental Medicine. Methods : Using the Pub med on line site; search terms: atopic dermatitis, field as title/abstract, limitation as published in the last 3 years, only items with links to full text, Humans, Clinical Trial, English. I observed the study contents of all this research and focused on the classification of treatments. I also observed of AD clinical trials registered on a clinical trial site(www.clinicaltrial.gov) on 23rd of June, 2007: study contents, localization and study designs. Results : Through the Pub Med site, I found 169 articles. Classified according to study subject, the studies related to treatment were 114(67.5%); physiology, pathology and prevention 12(7.1%); Diagnosis and Evaluation(7.1%); psychological aspects including quality of life 10(5.9%); diet and management 10(5.9%); epidemiology 7(4.1%); and others 7(4.1%). However, the treatment study of herb-medicine as intervention showed only 1 article. Futhermore, it wasn't based on Oriental Medicine philosophy. In the clinical trial site, there were 31 studies in which patients were recruited or planned for the future. The study on efficacy and safety of the medicine produced 14 trials, 5 comparative trials, 2 phototherapy, 2 diagnosis, 6 physiology and pathology, and 2 epidemiology. The trial institutions were concentrated in U.S.A. Conclusion : I suggest we'd better try to make a good clinical guideline and standardization of diagnosis and herb-medicine in order to develop a clinical study methodology of AD as soon as possible in the future. Even though it 's very hard to find the study methodology, we should aim to achieve positive results and show the evidence of the efficacy and safety of herb-medicine treatment for AD using Oriental Medicine.

참고문헌 (17)

  1. "based medicine: how to practice and teach EBM", pp.71~ (2004), Churchill Livingstone, London
  2. "crossover study pof cyslosporin in adults with severe refractory atopic dermatitis", pp.137~140 (1991)
  3. "Cyclosporin greatly improves the quality of life of adults with severe atopic dermatitis", pp.422~430 (1993)
  4. "Health services research- a radical approach to cross the research and development divide?", pp.55~ (1996), Research and Development for NHS. Oxford
  5. "Evidence-based Healthcare: how to make health policy and management decisions", pp.61~ (1998), Edinburgh: Churchill Livingstone
  6. "Comparative effect of tacrolimus and betamethasone valerate on the passive sustainable hydration of the stratum corneum in atopic dermatitis", 214(4), pp.328~332 (2007)
  7. "Staphylococcus colonization in atopic dermatitis treated with fluticasone or tacrolimus with or without antibiotics", 98(1), pp.51~56 (2007)
  8. "Low systemic absorption and good tolerability of pimecrolimus, administered as 1 % cream(Elidel) in infants with atopic dermatitis-a multicenter, 3 week, open- label study", 22(5), pp.465~471 (2005)
  9. "UVA-1 cold light therapy in the treatment of atopic dermatitis: 61 patients treated in the Leiden University Medical Center", 21(2), pp.93~96 (2005)
  10. "Pimecrolimus and narrowband UVB as monotherapy or combination therapy in children and adolescents with atopic germatitis", 86(1), pp.34~38 (2006)
  11. "Does narrow-band ultraviolet B phototheraphy work in atopic dermatitis through a local or a systemic effect?", 21(6), pp.333~335 (2005)
  12. "Optimized UVB tratment of atopic dermatitis using skin reflectance measurements. A controlled, left-right comparison trial", 85(2), pp.144~146 (2005)
  13. "UVA", UVB phototherapy for atopic dermatitis revisited, 2004, pp.15(4), 239~234
  14. "Cutaneous immunological activation elicited by a low-fluence pulsed dye laser", 153, pp.57~62 (2005)
  15. "Treatment of atopic dermatitis with herbal combination of Eleutherococcus, Achillea millefolium, and Lamium album has no advantage over placebo: a double blind, placebo-controlled, randomized trial", 52(4), pp.691~693 (2005)
  16. "Novel unconventional therapeutic approaches to atopic eczema", 201, pp.191~195 (2000)
  17. "Available site at: http:", pp.2007[DOI]

관련 논문AI추천

이 간행물의 다른 논문 (26건)