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논문KCI 등재

아토피피부염 병태생리에 대한 최신 지견

Advances In the Pathophysiology of Atopic Dermatitis

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대한 소아알레르기 호흡기학회 (The Korean Academy Of Pediatric Allergy And Respiratory Disease)|2006.09|Allergy Asthma & Respiratory Disease (알레르기 천식 호흡기질환)|제16권 제3호|pp. 189-196

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참고문헌

주제분류소아과학

초록

Abstract

Atopic dermatitis is a common chronic inflammatory skin disease often preceding the development of asthma and allergic disorders, such as food allergy or allergic rhinoconjunctivitis. The incidence of atopic dermatitis is increasing, and this poses a major burden on health care costs. The pathophysiology of atopic dermatitis has long remained enigmatic, but much scientific effort has been invested in elucidating the genetic background and the immunological mechanisms underlying atopic dermatitis. Pathophysiology involves a complex series of interactions between resident and infiltrating cells orchestrated by proinflammatory cytokines and chemokines. A deficiency of antimicrobial peptides might contribute to the propensity for colonization or infection by microbial organisms seen in atopic dermatitis. New management approaches have evolved form advances in our understanding of the pathophysiology of this common skin disorder.

참고문헌 (12)

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  2. "Recent highlights in the pathophysiology of atopic eczema", 136, pp.191~197 (2005)
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  4. "A scientific look at seasonality of symptom severity in atopic dermatitis", 124, pp.18~19 (2005)
  5. "The skin barrier and use of moisturizers in atopic dermatitis", 21, pp.145~157 (2003)
  6. "Immune mechanisms leading to atopic dermatitis", 112, pp.128~139 (2003)
  7. "Animal models of atopic dermatitis", 21, pp.122~133 (2003)
  8. "Measuring atopic dermatitis severity in randomized controlled clinical trials:what exactly are we measuring", 120, pp.932~941 (2003)
  9. "The role of lymphocytes in healthy and eczematous skin", 1, pp.455~460 (2001)
  10. "Eicosanoids in inflammatory skin diseases", 63, pp.43~54 (2000)
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  12. "Allergen sensitization through the skin induces systemic allergic responses", 106, pp.258~263 (2000)

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