Melanosis Ilei Associated with Chronic Ingestion of Oral Iron
0
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
Melanosis can affect various parts of the gastrointestinal tract. Melanosis of the colon is not uncommon, while melanosis of the ileum is extremely rare. We report a case of melanosis ilei associated with chronic ingestion of oral iron (256 mg of ferrous sulfate once or twice daily for approximately 5 years) in a 32-year-old woman with end-stage renal disease. The findings of a colonoscopy, which was performed as a part of her medical checkup, were normal up to the cecum; however, numerous brownish-black punctuate pigmentations of the ileal mucosa were observed. Microscopic examination revealed hemosiderosis in the lamina propria of the ileal mucosa, particularly at the tips of villi. The diagnosis of melanosis (hemosiderosis) ilei was made based on the endoscopic and histological findings.
Abstract
Melanosis can affect various parts of the gastrointestinal tract. Melanosis of the colon is not uncommon, while melanosis of the ileum is extremely rare. We report a case of melanosis ilei associated with chronic ingestion of oral iron (256 mg of ferrous sulfate once or twice daily for approximately 5 years) in a 32-year-old woman with end-stage renal disease. The findings of a colonoscopy, which was performed as a part of her medical checkup, were normal up to the cecum; however, numerous brownish-black punctuate pigmentations of the ileal mucosa were observed. Microscopic examination revealed hemosiderosis in the lamina propria of the ileal mucosa, particularly at the tips of villi. The diagnosis of melanosis (hemosiderosis) ilei was made based on the endoscopic and histological findings.
참고문헌 (13)
- Ghadially FN, "Melanoses of the gastrointestinal tract", Histopathology, 25, pp.197~207 (1994)
- Won KH, "Melanosis of the ileum. in: Case report and electron microscopic study", Am J Dig Dis, 15, pp.57~64 (1970)
- Ghadially FN, "Melanosis (haemosiderosis) ilei", J Submicrosc Cytol Pathol, 26, pp.461~465 (1994)
- Lee TH, "Melanosis ilei associated with chronic ingestion of edible charcoal", Gastrointest Endosc, 67, pp.1174~ (2008)
- 김명석, "장기간 숯 섭취 후 발생한 회장 흑색증 2예", 대한소화기내시경학회지, 36(1), pp.36~39 (2008), 대한소화기내시경학회
- Batistatou A, "Melanosis intestini: case report", Diagn Pathol, 1, pp.3~ (2006)
- Ghadially FN, "An electron-microscope and histochemical study of melanosis coli", J Pathol Bacteriol, 92, pp.313~317 (1966)
- Giusto D, "Pseudomelanosis duodeni: associated with multiple clinical conditions and unpredictable iron stainability - a case series", Endoscopy, 40, pp.165~167 (2008)
- Pounder DJ, "Ultrastructure and electron-probe x-ray analysis of the pigment in melanosis duodeni", J Submicrosc Cytol, 14, pp.389~400 (1982)
- Banai J, "Melanosis jejuni", Gastrointest Endosc, 45, pp.432~434 (1997)
- Ghadially FN, "A comparison of the ultrastructure of pigment granules in melanosis ilei and pulmonary lymph nodes", Histopathology, 23, pp.167~172 (1993)
- Qutob T, "Terminal ileum hemosiderosis in association with hereditary hemochromatosis", J Clin Gastroenterol, 38, pp.465~ (2004)
- Pohl J, "Computed virtual chromoendoscopy: a new tool for enhancing tissue surface structures", Endoscopy, 39, pp.80~83 (2007)