Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells

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참고문헌 (33)

1. Sirica AE, "Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy", Hepatology, 41, pp.5~15 (2005)
2. Jarnagin WR, "Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma", Ann Surg, 234, pp.507~517 (2001)
3. Ustundag Y, "Cholangiocarcinoma: a compact review of the literature", World J Gastroenterol, 14, pp.6458~6466 (2008)
4. Murakami Y, "Gemcitabine-based adjuvant chemotherapy improves survival after aggressive surgery for hilar cholangiocarcinoma", J Gastrointest Surg, 13, pp.1470~1479 (2009)
5. Lee GW, "Combination chemotherapy with gemcitabine and cisplatin as first-line treatment for immunohistochemically proven cholangiocarcinoma", Am J Clin Oncol, 29, pp.127~131 (2006)
6. Blechacz B, "Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment", Hepatology, 48, pp.308~321 (2008)
7. Rosen ED, "PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth", J Biol Chem, 276, pp.37731~37734 (2001)
8. Gauthaman K, "Statins, stem cells, and cancer", J Cell Biochem, 106, pp.975~983 (2009)
9. Blanco-Colio LM, "3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation", Atherosclerosis, 161, pp.17~26 (2002)
10. Danesh FR, "3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase", p21signaling pathway: implications for diabetic nephropathy, 2002, pp.99, 8301~8305
11. Takemoto M, "Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors", Arterioscler Thromb Vasc Biol, 21, pp.1712~1719 (2001)
12. Miller T, "Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity", Dig Liver Dis, 43, pp.395~403 (2011)
13. El-Serag HB, "Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes", Gastroenterology, 136, pp.1601~1608 (2009)
14. Hachem C, "Statins and the risk of colorectal carcinoma: a nested case-control study in veterans with diabetes", Am J Gastroenterol, 104, pp.1241~1248 (2009)
15. Poynter JN, "Statins and the risk of colorectal cancer", N Engl J Med, 352, pp.2184~2192 (2005)
16. Lee J, "HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha", PPARgamma and ABCA1 in cultured gallbladder epithelial cells, 2010, pp.55, 292~299
17. Adachi Y, "A candidate targeting molecule of insulin-like growth factor-I receptor for gastrointestinal cancers", World J Gastroenterol, 16, pp.5779~5789 (2010)
18. Baserga R, "The insulin-like growth factor I receptor: a key to tumor growth?", Cancer Res, 55, pp.249~252 (1995)
19. Yu H, "Role of the insulin-like growth factor family in cancer development and progression", J Natl Cancer Inst, 92, pp.1472~1489 (2000)
20. Alvaro D, "Estrogens and insulinlike growth factor 1 modulate neoplastic cell growth in human cholangiocarcinoma", Am J Pathol, 169, pp.877~888 (2006)
21. Ku JL, "Establishment and characterisation of six human biliary tract cancer cell lines", Br J Cancer, 87, pp.187~193 (2002)
22. Alupei MC, "Cytotoxicity of lipophilic statins depends on their combined actions on HIF-1α expression and redox status in B16.F10 melanoma cells", Anticancer Drugs, 25, pp.393~405 (2014)
23. Kato S, "Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase", J Cell Mol Med, 14, pp.1180~1193 (2010)
24. Ogunwobi OO, "Statins inhibit proliferation and induce apoptosis in Barrett’s esophageal adenocarcinoma cells", Am J Gastroenterol, 103, pp.825~837 (2008)
25. Wood WG, "Statins, Bcl-2, and apoptosis: cell death or cell protection?", Mol Neurobiol, 48, pp.308~314 (2013)
26. Pollak M, "Insulin and insulin-like growth factor signalling in neoplasia", Nat Rev Cancer, 8, pp.915~928 (2008)
27. Gallagher EJ, "The proliferating role of insulin and insulin-like growth factors in cancer", Trends Endocrinol Metab, 21, pp.610~618 (2010)
28. Sekine Y, "Simvastatin inhibits the proliferation of human prostate cancer PC-3cells via down-regulation of the insulin-like growth factor 1 receptor", Biochem Biophys Res Commun, 372, pp.356~361 (2008)
29. Cho SJ, "Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice", Int J Cancer, 123, pp.951~957 (2008)
30. Kim W, "Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma", Cancer Chemother Pharmacol, 64, pp.497~507 (2009)
31. Kim ST, "Simvastatin plus capecitabinecisplatin versus placebo plus capecitabine-cisplatin in patients with previously untreated advanced gastric cancer: a double-blind randomised phase 3 study", Eur J Cancer, 50, pp.2822~2830 (2014)
32. Kamigaki M, "Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells", Int J Oncol, 39, pp.561~568 (2011)
33. Cai JP, "Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1", TS downregulation might be the mechanism, 2013, pp.24, 1020~1029

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