Pitavastatin Induces Apoptosis of Cutaneous Squamous Cell Carcinoma Cells through Geranylgeranyl PyrophosphateDependent c-Jun N-Terminal Kinase Activatio

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참고문헌 (32)

1. Green AC, "Cutaneous squamous cell carcinoma : an epidemiological review", Br J Dermatol, 177, pp.373~381 (2017)
2. Rodust PM, "UV-induced squamous cell carcinoma--a role for antiapoptotic signalling pathways", Br J Dermatol, 161(Suppl 3), pp.107~115 (2009)
3. de Jager TL, "Ultraviolet light induced generation of reactive oxygen species", Adv Exp Med Biol, 996, pp.15~23 (2017)
4. Que SKT, "Cutaneous squamous cell carcinoma : Incidence, risk factors, diagnosis, and staging", J Am Acad Dermatol, 78, pp.237~247 (2018)
5. Sherwood V, "WNT signaling in cutaneous squamous cell carcinoma : a future treatment strategy?", J Invest Dermatol, 136, pp.1760~1767 (2016)
6. Li XM, "KLF4suppresses the tumor activity of cutaneous squamous cell carcinoma(SCC)cells via the regulation of SMAD signaling and SOX2expression", Biochem Biophys Res Commun, 516, pp.1110~1115 (2019)
7. Szeimies RM, "Towards a more specific therapy : targeting nonmelanoma skin cancer cells", Br J Dermatol, 154(Suppl 1), pp.16~21 (2006)
8. Tricarico PM, "Mevalonate pathway blockade, mitochondrial dysfunction and autophagy : a possible link", Int J Mol Sci, 16, pp.16067~16084 (2015)
9. Hoy SM, "Pitavastatin : a review in hypercholesterolemia", Am J Cardiovasc Drugs, 17, pp.157~168 (2017)
10. Hu T, "Cholesterollowering drug pitavastatin targets lung cancer and angiogenesis via suppressing prenylation-dependent Ras", Raf, Akt, pp.mTOR signaling, Anticancer Drugs[DOI]
11. Lee N, "Pitavastatin induces apoptosis in oral squamous cell carcinoma through activation of FOXO3a", J Cell Mol Med, 24, pp.7055~7066 (2020)
12. Zhao W, "Different effects of statins on induction of diabetes mellitus : an experimental study", Drug Des Devel Ther, 9, pp.6211~6223 (2015)
13. Kamigaki M, "Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells", Int J Oncol, 39, pp.561~568 (2011)
14. 하유미, "Pitavastatin Regulates Ang II Induced Proliferation and Migration via IGFBP-5 in VSMC", The Korean Journal of Physiology & Pharmacology, 19(6), pp.499~506 (2015), 대한약리학회
15. Rheinwald JG, "Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas", Cancer Res, 41, pp.1657~1663 (1981)
16. Wiemer AJ, "Geranylgeranyl diphosphate synthase : an emerging therapeutic target", Clin Pharmacol Ther, 90, pp.804~812 (2011)
17. Mi W, "Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration", Oncogene, 34, pp.3095~3106 (2015)
18. Li X, "Inhibition of protein geranylgeranylation and RhoA", RhoA kinase pathway induces apoptosis in human endothelial cells, 2002, pp.277, 15309~15316
19. Nguyen LK, "Rac1 and RhoA : networks, loops and bistability", Small GTPases, 9, pp.316~321 (2018)
20. Jin S, "Rac1 mediates intestinal epithelial cell apoptosis via JNK", Am J Physiol Gastrointest Liver Physiol, 291, pp.G1137~G1147 (2006)
21. Muñoz-Alonso MJ, "Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1", c-Jun NH2-terminal kinase activation in human melanoma cells, 2008, pp.324, 1093~1101
22. Goka ET, "Rac signaling drives clear cell renal carcinoma tumor growth by priming the tumor microenvironment for an angiogenic switch", Mol Cancer Ther, 19, pp.1462~1473 (2020)
23. Liu J, "Role of JNK activation in apoptosis : a double-edged sword", Cell Res, 15, pp.36~42 (2005)
24. Hanusova V, "Potential anticancer drugs commonly used for other indications", Curr Cancer Drug Targets, 15, pp.35~52 (2015)
25. 김경일, "Inhibitory Effect of Mitoxantrone on Collagen Synthesis in Dermal Fibroblasts", Annals of Dermatology, 34(3), pp.206~211 (2022), 대한피부과학회[DOI]
26. Kim KI, "Sorafenib induces pigmentation via the regulation of β-catenin signalling pathway in melanoma cells", Exp Dermatol, 31, pp.57~63 (2022)
27. Noguera-Salvà MA, "Role of the C-terminal basic amino acids and the lipid anchor of the Gγ2 protein in membrane interactions and cell localization", Biochim Biophys Acta Biomembr, 1859(9 Pt B), pp.1536~1547 (2017)
28. Riganti C, "Statins-mediated inhibition of rho GTPases as a potential tool in anti-tumor therapy", Mini Rev Med Chem, 8, pp.609~618 (2008)
29. Svensmark JH, "Rho GTPases in cancer : friend or foe?", Oncogene, 38, pp.7447~7456 (2019)
30. Debaugnies M, "YAP and TAZ are essential for basal and squamous cell carcinoma initiation", EMBO Rep, 19, pp.e45809~ (2018)
31. Liang SL, "Lovastatin-induced apoptosis in macrophages through the Rac1", Cdc42, J Immunol, pp.2006, 177[DOI]
32. Healy A, "Statins disrupt macrophage Rac1 regulation leading to increased atherosclerotic plaque calcification", Arterioscler Thromb Vasc Biol, 40, pp.714~732 (2020)

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