Molecular Features of the Serrated Pathway to Colorectal Cancer: Current Knowledge and Future Directions

키워드

참고문헌 (78)

1. Ferlay J, "Cancer incidence and mortality worldwide : sources, methods and major patterns in GLOBOCAN 2012", Int J Cancer, 136, pp.E359~ (2015)
2. Jass JR, "Sialic acid and epithelial differentiation in colorectal polyps and cancer : a morphological, mucin and lectin histochemical study", Pathology, 24, pp.233~242 (1992)
3. Vogelstein B, "Genetic alterations during colorectal-tumor development", N Engl J Med, 319, pp.525~532 (1988)
4. Fearon ER, "A genetic model for colorectal tumorigenesis", Cell, 61, pp.759~767 (1990)
5. Mäkinen MJ, "Colorectal serrated adenocarcinoma", Histopathology, 50, pp.131~150 (2007)
6. Kambara T, "BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum", Gut, 53, pp.1137~1144 (2004)
7. O’Brien MJ, "Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points", Am J Surg Pathol, 30, pp.1491~1501 (2006)
8. Longacre TA, "Mixed hyperplastic adenomatous polyps", serrated adenomas : a distinct form of colorectal neoplasia, 1990, pp.14, 524~537
9. Torlakovic E, "Serrated adenomatous polyposis in humans", Gastroenterology, 110, pp.748~755 (1996)
10. Rex DK, "Serrated lesions of the colorectum : review and recommendations from an expert panel", Am J Gastroenterol, 107, pp.1315~1329 (2012)
11. Bosman FT, "WHO classification of tumours of the digestive system. Volume 3", pp.417~ (2010), International Agency for Research on Cancer
12. East JE, "British Society of Gastroenterology position statement on serrated polyps in the colon and rectum", Gut, 66, pp.1181~1196 (2017)
13. Toyota M, "CpG island methylator phenotypes in aging and cancer", Semin Cancer Biol, 9, pp.349~357 (1999)
14. Bird A, "DNA methylation patterns and epigenetic memory", Genes Dev, 16, pp.6~21 (2002)
15. Herman JG, "Gene silencing in cancer in association with promoter hypermethylation", N Engl J Med, 349, pp.2042~2054 (2003)
16. Bettington M, "Clinicopathological and molecular features of sessile serrated adenomas with dysplasia or carcinoma", Gut, 66, pp.97~106 (2017)
17. Toyota M, "CpG island methylator phenotype in colorectal cancer", Proc Natl Acad Sci U S A, 96, pp.8681~8686 (1999)
18. Weisenberger DJ, "CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer", Nat Genet, 38, pp.787~793 (2006)
19. Ogino S, "Evaluation of markers for CpG island methylator phenotype(CIMP)in colorectal cancer by a large population-based sample", J Mol Diagn, 9, pp.305~314 (2007)
20. Samowitz WS, "Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer", Gastroenterology, 129, pp.837~845 (2005)
21. Bae JM, "Distinct clinical outcomes of two CIMP-positive colorectal cancer subtypes based on a revised CIMP classification system", Br J Cancer, 116, pp.1012~1020 (2017)
22. Bae JM, "Are clinicopathological features of colorectal cancers with methylation in half of CpG island methylator phenotype panel markers different from those of CpG island methylator phenotype-high colorectal cancers?", Hum Pathol, 47, pp.85~94 (2016)
23. Kim JH, "Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers", Virchows Arch, 455, pp.485~494 (2009)
24. Tanaka N, "Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer", Am J Pathol, 177, pp.2731~2740 (2010)
25. Sánchez-Vega F, "CpG island methylator phenotype in adenocarcinomas from the digestive tract : methods, conclusions, and controversies", World J Gastrointest Oncol, 9, pp.105~120 (2017)
26. Lengauer C, "Genetic instabilities in human cancers", Nature, 396, pp.643~649 (1998)
27. Tuppurainen K, "Morphology and microsatellite instability in sporadic serrated and nonserrated colorectal cancer", J Pathol, 207, pp.285~294 (2005)
28. Boland CR, "Microsatellite instability in colorectal cancer", Gastroenterology, 138, pp.2073~2087 (2010)
29. Hashimoto T, "WNT pathway gene mutations are associated with the presence of dysplasia in colorectal sessile serrated adenoma", polyps, 2017, pp.41, 1188~1197
30. Umar A, "Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer(Lynch syndrome)and microsatellite instability", J Natl Cancer Inst, 96, pp.261~268 (2004)
31. Sebolt-Leopold JS, "Targeting the mitogen-activated protein kinase cascade to treat cancer", Nat Rev Cancer, 4, pp.937~947 (2004)
32. Rajagopalan H, "Tumorigenesis : RAF", RAS oncogenes and mismatch-repair status, 2002, pp.418, 934~
33. Sakai E, "Genetic and epigenetic aberrations occurring in colorectal tumors associated with serrated pathway", Int J Cancer, 138, pp.1634~1644 (2016)
34. Pai RK, "Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix", Hum Pathol, 45, pp.227~235 (2014)
35. Kim KM, "Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma", polyps from Korea, 2011, pp.35, 1274~1286
36. Beach R, "BRAF mutations in aberrant crypt foci and hyperplastic polyposis", Am J Pathol, 166, pp.1069~1075 (2005)
37. Fang M, "The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype", Mol Cell, 55, pp.904~915 (2014)
38. Capper D, "Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody", Acta Neuropathol, 122, pp.11~19 (2011)
39. Dinges HC, "Validation of a manual protocol for BRAF V600E mutation-specific immunohistochemistry", Appl Immunohistochem Mol Morphol, 23, pp.382~388 (2015)
40. Affolter K, "BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma", Genes Chromosomes Cancer, 52, pp.748~752 (2013)
41. Andreyev HJ, "Kirsten ras mutations in patients with colorectal cancer : the multicenter"RASCAL"study", J Natl Cancer Inst, 90, pp.675~684 (1998)
42. Samowitz WS, "Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival : a population-based study", Cancer Epidemiol Biomarkers Prev, 9, pp.1193~1197 (2000)
43. Stefanius K, "Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma", Histopathology, 58, pp.679~692 (2011)
44. Sugai T, "Molecular profiling based on KRAS", BRAF mutation, methylation, and microsatellite statuses in serrated lesions, 2018, pp.63, 2626~2638
45. Piton N, "KRAS and BRAF mutation detection: is immunohistochemistry a possible alternative to molecular biology in colorectal cancer?", Gastroenterol Res Pract, 2015, pp.753903~ (2015)
46. Cancer Genome Atlas Network, "Comprehensive molecular characterization of human colon and rectal cancer", Nature, 487, pp.330~337 (2012)
47. Borowsky J, "The role of APC in WNT pathway activation in serrated neoplasia", Mod Pathol, 31, pp.495~504 (2018)
48. Bond CE, "RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis", Oncotarget, 7, pp.70589~70600 (2016)
49. Murakami T, "Distinct WNT", β-catenin signaling activation in the serrated neoplasia pathway and the adenoma-carcinoma sequence of the colorectum, 2015, pp.28, 146~158
50. Fennell LJ, "RNF43 is mutated less frequently in Lynch syndrome compared with sporadic microsatellite unstable colorectal cancers", Fam Cancer, 17, pp.63~69 (2018)
51. Tsai JH, "RNF43 is an early and specific mutated gene in the serrated pathway, with increased frequency in traditional serrated adenoma and its associated malignancy", Am J Surg Pathol, 40, pp.1352~1359 (2016)
52. Leggett B, "Role of the serrated pathway in colorectal cancer pathogenesis", Gastroenterology, 138, pp.2088~2100 (2010)
53. Kriegl L, "Up and downregulation of p16(Ink4a)expression in BRAF-mutated polyps", adenomas indicates a senescence barrier in the serrated route to colon cancer, 2011, pp.24, 1015~1022
54. Bettington ML, "A clinicopathological and molecular analysis of 200 traditional serrated adenomas", Mod Pathol, 28, pp.414~427 (2015)
55. Suzuki H, "IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype", Carcinogenesis, 31, pp.342~349 (2010)
56. Bond CE, "p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers", Int J Cancer, 130, pp.1567~1576 (2012)
57. Ito M, "MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions", Int J Cancer, 135, pp.2507~2515 (2014)
58. Slattery ML, "The miRNA landscape of colorectal polyps", Genes Chromosomes Cancer, 56, pp.347~353 (2017)
59. Tsikitis VL, "MicroRNA signatures of colonic polyps on screening and histology", Cancer Prev Res(Phila), 9, pp.942~949 (2016)
60. Kanth P, "Small RNA sequencing of sessile serrated polyps identifies microRNA profile associated with colon cancer", Genes Chromosomes Cancer, 58, pp.23~33 (2019)
61. Renaud F, "The serrated neoplasia pathway of colorectal tumors : identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential", Int J Cancer, 138, pp.1472~1481 (2016)
62. Kim YH, "Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps", Int J Cancer, 123, pp.2587~2593 (2008)
63. Spring KJ, "High prevalence of sessile serrated adenomas with BRAF mutations : a prospective study of patients undergoing colonoscopy", Gastroenterology, 131, pp.1400~1407 (2006)
64. Yang S, "BRAF and KRAS mutations in hyperplastic polyps and serrated adenomas of the colorectum : relationship to histology and CpG island methylation status", Am J Surg Pathol, 28, pp.1452~1459 (2004)
65. Sandmeier D, "Serrated polyps of the large intestine : a molecular study comparing sessile serrated adenomas and hyperplastic polyps", Histopathology, 55, pp.206~213 (2009)
66. Burnett-Hartman AN, "Genomic aberrations occurring in subsets of serrated colorectal lesions but not conventional adenomas", Cancer Res, 73, pp.2863~2872 (2013)
67. Yamane LS, "KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy", Oncol Rep, 32, pp.1419~1426 (2014)
68. Schreiner MA, "Proximal and large hyperplastic and nondysplastic serrated polyps detected by colonoscopy are associated with neoplasia", Gastroenterology, 139, pp.1497~1502 (2010)
69. García-Solano J, "Clinicopathologic study of 85 colorectal serrated adenocarcinomas : further insights into the full recognition of a new subset of colorectal carcinoma", Hum Pathol, 41, pp.1359~1368 (2010)
70. 이예영, "CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway", Gut and Liver, 11(1), pp.38~46 (2017), 거트앤리버 소화기연관학회협의회
71. Ogino S, "Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low(CIMP-low)in colorectal cancer", Gut, 56, pp.1564~1571 (2007)
72. Bettington M, "Sessile serrated adenomas in young patients may have limited risk of malignant progression", J Clin Gastroenterol, 53, pp.e113~ (2019)
73. Yagi K, "Three DNA methylation epigenotypes in human colorectal cancer", Clin Cancer Res, 16, pp.21~33 (2010)
74. Serra RW, "A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype", Elife, 3, pp.e02313~ (2014)
75. Ogino S, "CpG island methylator phenotype-low(CIMP-low)in colorectal cancer : possible associations with male sex and KRAS mutations", J Mol Diagn, 8, pp.582~588 (2006)
76. Rosenberg DW, "Mutations in BRAF and KRAS differentially distinguish serrated versus nonserrated hyperplastic aberrant crypt foci in humans", Cancer Res, 67, pp.3551~3554 (2007)
77. Chen D, "BRAFV600E mutation and its association with clinicopathological features of colorectal cancer : a systematic review and meta-analysis", PLoS One, 9, pp.e90607~ (2014)
78. Lannagan TRM, "Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis", Gut, 68, pp.684~692 (2019)

관련 논문AI추천