Primary Squamous Cell Carcinoma of the Liver Initially Presenting with Pseudoachalasia
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Pseudoachalasia secondary to primary squamous cell carcinoma (SCC) of the liver is extremely rare and has not been reported until now. Here, we report a unique case of primary SCC of the liver initially presenting with progressive dysphagia along with short periods of signifi cant weight loss. A 58-yearold man initially presented with progressive dysphagia along with significant weight loss over brief periods of time. The radiographic and manometric fi ndings were consistent with achalasia. Subsequent esophagogastroduodenoscopy revealed a moderately dilated esophagus without evidence of neoplasm or organic obstruction. However, firm resistance was encountered while traversing the esophagogastric junction (EGJ), although no mucosal lesion was identifi ed. Due to the clinical suspicion of the presence of a malignant tumor,endoscopic ultrasonography (EUS) and computed tomography scans of the chest and abdomen were obtained. A huge hepatic mass with irregular margins extending to the EGJ was found. EUS-guided fine-needle aspiration was performed,and the mass was diagnosed as a primary SCC of the liver by immunohistochemical staining.
Abstract
Pseudoachalasia secondary to primary squamous cell carcinoma (SCC) of the liver is extremely rare and has not been reported until now. Here, we report a unique case of primary SCC of the liver initially presenting with progressive dysphagia along with short periods of signifi cant weight loss. A 58-yearold man initially presented with progressive dysphagia along with significant weight loss over brief periods of time. The radiographic and manometric fi ndings were consistent with achalasia. Subsequent esophagogastroduodenoscopy revealed a moderately dilated esophagus without evidence of neoplasm or organic obstruction. However, firm resistance was encountered while traversing the esophagogastric junction (EGJ), although no mucosal lesion was identifi ed. Due to the clinical suspicion of the presence of a malignant tumor,endoscopic ultrasonography (EUS) and computed tomography scans of the chest and abdomen were obtained. A huge hepatic mass with irregular margins extending to the EGJ was found. EUS-guided fine-needle aspiration was performed,and the mass was diagnosed as a primary SCC of the liver by immunohistochemical staining.
참고문헌 (12)
- Naik S, "Primary squamous cell carcinoma of the liver", J Gastrointestin Liver Dis, 18, pp.487~489 (2009)
- Lee HL, "Primary squamous cell carcinoma of the liver: a successful surgically treated case", World J Gastroenterol, 12, pp.5419~5421 (2006)
- Yagi H, "Squamous cell carcinoma of the liver originating from non-parasitic cysts after a 15 year followup", Eur J Gastroenterol Hepatol, 16, pp.1051~1056 (2004)
- Kahrilas PJ, "Comparison of pseudoachalasia and achalasia", Am J Med, 82, pp.439~446 (1987)
- Parkman HP, "Malignancy-induced secondary achalasia", Dysphagia, 9, pp.292~296 (1994)
- Gockel I, "Pseudoachalasia: a case series and analysis of the literature", Scand J Gastroenterol, 40, pp.378~385 (2005)
- Liu W, "The pathogenesis of pseudoachalasia: a clinicopathologic study of 13 cases of a rare entity", Am J Surg Pathol, 26, pp.784~788 (2002)
- Jung Ho Park, "An Unusual Case of Submucosal Invasion of Esophageal Squamous Cell Carcinoma Mistaken as Primary Achalasia", Journal of Neurogastroenterology and Motility (JNM), 16(2), pp.194~198 (2010), 대한소화기 기능성질환∙운동학회
- Tucker HJ, "Achalasia secondary to carcinoma: manometric and clinical features", Ann Intern Med, 89, pp.315~318 (1978)
- Sandler RS, "Failure of clinical criteria to distinguish between primary achalasia and achalasia secondary to tumor", Dig Dis Sci, 27, pp.209~213 (1982)
- Lorenz R, "The value of endoscopy and endosonography in the diagnosis of the dysphagic patient", Dysphagia, 8, pp.91~97 (1993)
- Carter M, "Differentiation of achalasia from pseudoachalasia by computed tomography", Am J Gastroenterol, 92, pp.624~628 (1997)