초음파 내시경 유도하 조직 검사로 진단된 담낭의 원발성 편평상피암 1예
Primary Squamous Cell Carcinoma of the Gallbladder Diagnosed by Endoscopic Ultrasound-Guided Fine Needle Biopsy
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Squamous cell carcinoma of the gallbladder (GB) is uncommon and often presents at an advanced stage; therefore, it is associated with more aggressive behavior and a worse prognosis than those of adenocarcinoma. Herein, we report the case of an 82-year-old woman presenting a weight loss of 5 kg and epigastric discomfort over the previous 3 months. Abdominal computed tomography and magnetic resonance cholangiopancreatography revealed an infiltrative mass in the GB with hepatic invasion. Endoscopic ultrasound-guided fine needle biopsy using a 20-G core needle was performed, and the pathological examination revealed keratin pearls and an intracellular bridge, which are characteristics of squamous cell differentiation consistent with squamous cell carcinoma. Endoscopic ultrasound-guided fine needle biopsy was useful for obtaining an accurate histological diagnosis of GB masses without the need for surgery.
Abstract
Squamous cell carcinoma of the gallbladder (GB) is uncommon and often presents at an advanced stage; therefore, it is associated with more aggressive behavior and a worse prognosis than those of adenocarcinoma. Herein, we report the case of an 82-year-old woman presenting a weight loss of 5 kg and epigastric discomfort over the previous 3 months. Abdominal computed tomography and magnetic resonance cholangiopancreatography revealed an infiltrative mass in the GB with hepatic invasion. Endoscopic ultrasound-guided fine needle biopsy using a 20-G core needle was performed, and the pathological examination revealed keratin pearls and an intracellular bridge, which are characteristics of squamous cell differentiation consistent with squamous cell carcinoma. Endoscopic ultrasound-guided fine needle biopsy was useful for obtaining an accurate histological diagnosis of GB masses without the need for surgery.
참고문헌 (10)
- Henson DE, "Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates", Cancer, 70, pp.1493~1497 (1992)
- Charbit A, "Relation between the pathological nature and the growth rate of human tumors", Eur J Cancer, 7, pp.307~315 (1971)
- Nishihara K, "Adenosquamous carcinoma of the gall-bladder with gastric foveolar-type epithelium", Pathol Int, 45, pp.250~256 (1995)
- Chan KM, "Adenosquamous", squamous cell carcinoma of the gallbladder, 2007, pp.95, 129~134
- Dodd LG, "Fine-needle aspiration of primary gallbladder carcinoma", Diagn Cytopathol, 15, pp.151~156 (1996)
- Zargar SA, "USguided fine-needle aspiration biopsy of gallbladder masses", Radiology, 179, pp.275~278 (1991)
- Wu SS, "Ultrasound-guided percutaneous transhepatic fine needle aspiration cytology study of gallbladder polypoid lesions", Am J Gastroenterol, 91, pp.1591~1594 (1996)
- Jacobson BC, "EUS-guided FNA for the diagnosis of gallbladder masses", Gastrointest Endosc, 57, pp.251~254 (2003)
- Hijioka S, "Can EUS-guided FNA distinguish between gallbladder cancer and xanthogranulomatous cholecystitis", Gastrointest Endosc, 72, pp.622~627 (2010)
- Iwashita T, "Macroscopic on-site quality evaluation of biopsy specimens to improve the diagnostic accuracy during EUS-guided FNA using a 19-gauge needle for solid lesions : a single-center prospective pilot study(MOSE study)", Gastrointest Endosc, 81, pp.177~185 (2015)