Endoscopic Findings of Enteropathy-Associated T-Cell Lymphoma Type II: A Case Series
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. Two types of EATL have been reported. In contrast to the classic EATL type I, EATL type II occurs sporadically, is unrelated to celiac disease, and comprises 10% to 20 % of all EATL cases. A total of five cases of EATL type II were diagnosed at our clinic from January 2009 to September 2012. Four of the five patients were diagnosed with the help of endoscopy. Among the four patients, two of the cases involved both the small and large intestines, whereas in the other two patients, EATL was limited to the small intestine. Common endoscopic findings included innumerable fine granularities (also called mosaic mucosal patterns) and diffuse thickening of the mucosa with a semicircular shallow ulceration in the lesions of the small bowel. In contrast, the endoscopic findings of the colon were nonspecific and could not distinguish EATL type II from other diseases. There are only few published reports regarding the representative endoscopic findings of EATL. Here, we present the clinical and endoscopic findings of four cases of EATL type II diagnosed by endoscopy.
Abstract
Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. Two types of EATL have been reported. In contrast to the classic EATL type I, EATL type II occurs sporadically, is unrelated to celiac disease, and comprises 10% to 20 % of all EATL cases. A total of five cases of EATL type II were diagnosed at our clinic from January 2009 to September 2012. Four of the five patients were diagnosed with the help of endoscopy. Among the four patients, two of the cases involved both the small and large intestines, whereas in the other two patients, EATL was limited to the small intestine. Common endoscopic findings included innumerable fine granularities (also called mosaic mucosal patterns) and diffuse thickening of the mucosa with a semicircular shallow ulceration in the lesions of the small bowel. In contrast, the endoscopic findings of the colon were nonspecific and could not distinguish EATL type II from other diseases. There are only few published reports regarding the representative endoscopic findings of EATL. Here, we present the clinical and endoscopic findings of four cases of EATL type II diagnosed by endoscopy.
참고문헌 (11)
- Swerdlow SH, "WHO classification of tumours of haematopoietic and lymphoid tissues" (2008), IARC Press
- Tse E, "Type II enteropathy-associated Tcell lymphoma: a multicenter analysis from the Asia Lymphoma Study Group", Am J Hematol, 87, pp.663~668 (2012)
- Gale J, "Enteropathy-type intestinal T-cell lymphoma: clinical features and treatment of 31 patients in a single center", J Clin Oncol, 18, pp.795~803 (2000)
- Chan JK, "Type II enteropathy-associated T-cell lymphoma: a distinct aggressive lymphoma with frequent gamma delta T-cell receptor expression", Am J Surg Pathol, 35, pp.1557~1569 (2011)
- Ko YH, "Enteropathy-associated T-cell lymphoma: a clinicopathologic and array comparative genomic hybridization study", Hum Pathol, 41, pp.1231~1237 (2010)
- Chott A, "Most CD56+ intestinal lymphomas are CD8+CD5-T-cell lymphomas of monomorphic small to medium size histology", Am J Pathol, 153, pp.1483~1490 (1998)
- Tung CL, "Intestinal T-cell and natural killer-cell lymphomas in Taiwan with special emphasis on 2 distinct cellular types: natural killer-like cytotoxic T cell and true natural killer cell", Hum Pathol, 39, pp.1018~1025 (2008)
- Yanai S, "Endoscopic findings of enteropathy-type T-cell lymphoma", Endoscopy, 39(1), pp.E339~E340 (2007)
- Sato Y, "Endoscopic findings of enteropathy-type T-cell lymphoma by double-balloon enteroscopy and capsule endoscopy", Dig Endosc, 22, pp.243~245 (2010)
- Jun Yong Bae, "A Case of Enteropathy-Type T-Cell Lymphoma Diagnosed by Small Bowel Enteroscopy: A Perspective on Imaging-Enhanced Endoscopy", Gut and Liver, 6(4), pp.516~519 (2012), 거트앤리버 발행위원회
- Sieniawski M, "Evaluation of enteropathy-associated T-cell lymphoma comparing standard therapies with a novel regimen including autologous stem cell transplantation", Blood, 115, pp.3664~3670 (2010)