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인체 호흡 모사를 위한 기계적 장치 연구

The Study of Mechanical Simulation for Human Respiratory System

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A patient with respiratory disorders such as a sleep apnea is increasing as the obese patient increase on the modern society. Positive Airway Pressure (PAP) devices are used in curing patient with respiratory disorders and turn out to be efficacious for patients of 75%. However, these devices are required for evaluating their performance to improve their performance by the mechanical breathing simulator. Recently, the mechanical breathing simulator was studied by the real time feedback control. However, the mechanical breathing simulator by an open loop control was specially required in order to analyze the effect of flow rate and pressure after operating the breathing auxiliary devices. Therefore the aims of this study were to make the mechanical breathing simulator by a piston motion and a valve function from the characteristic test of valve and motor, and to duplicate the flow rate and pressure profiles of some breathing patterns: normal and three disorder patterns. The mechanical simulator is composed cylinder, valve, ball screw and the motor. Also, the characteristic test of the motor and the valve were accomplished in order to define the relationship between the characteristics of simulator and the breathing profiles. Then, the flow rate and pressure profile of human breathing patterns were duplicated by the control of motor and valve. The result showed that the simulator reasonably duplicated the characteristics of human patterns: normal, obstructive sleep apnea (OSA), mild hypopnea with snore and mouth expiration patterns. However, we need to improve this simulator in detail and to validate this method for other patterns

Abstract

A patient with respiratory disorders such as a sleep apnea is increasing as the obese patient increase on the modern society. Positive Airway Pressure (PAP) devices are used in curing patient with respiratory disorders and turn out to be efficacious for patients of 75%. However, these devices are required for evaluating their performance to improve their performance by the mechanical breathing simulator. Recently, the mechanical breathing simulator was studied by the real time feedback control. However, the mechanical breathing simulator by an open loop control was specially required in order to analyze the effect of flow rate and pressure after operating the breathing auxiliary devices. Therefore the aims of this study were to make the mechanical breathing simulator by a piston motion and a valve function from the characteristic test of valve and motor, and to duplicate the flow rate and pressure profiles of some breathing patterns: normal and three disorder patterns. The mechanical simulator is composed cylinder, valve, ball screw and the motor. Also, the characteristic test of the motor and the valve were accomplished in order to define the relationship between the characteristics of simulator and the breathing profiles. Then, the flow rate and pressure profile of human breathing patterns were duplicated by the control of motor and valve. The result showed that the simulator reasonably duplicated the characteristics of human patterns: normal, obstructive sleep apnea (OSA), mild hypopnea with snore and mouth expiration patterns. However, we need to improve this simulator in detail and to validate this method for other patterns

참고문헌 (9)

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  2. Tilkian, A. G, "Sleep-induced apnea syndrome: Prevalence of cardiac arrhythmias and their reversal after tracheostomy", Am J Med, 63, pp.348~ (1977)
  3. McArdle, N, "Long-term use of CPAP therapy for sleep apnea", hypopneas syndrome, 1999, pp.159, 1108~1114
  4. Verbraak, A. F. M, "A new approach to mechanical simu- lation of lung behaviour: pressure-controlled and time-related piston movement", Med. Biol.Eng.Comput, 39, pp.82~89 (2001)
  5. Smits, A. J, "A Physical Introduction to Fluid Mechanics", pp.370~3 (2000), New York: Wiley
  6. Melo, P. L, "Instrumentation for the Analysis of respiratory system disoders during sleep: Design and application", Rev. Sci. Instrum, 73(11), pp.3926~3932 (2002)
  7. Mešić, S, "Computer-controlled mechanical simulation of the artificially ventilated human respiratory system", IEEE Transactions on Biomedical Engineering June, 50(6), pp.731~743 (2003)
  8. Rigau, J, "Bench model to simulate upper airway obstruction for analyzing automatic continuous positive airway pressure devices", Chest Journal August, 130, pp.350~361 (2006)
  9. S.I.Rubinow, "Introduction to Mathe matical Biology" (1975), New York:Academic Press

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