본태성 진전 환자의 진전특성에 대한 수행과제 및 부위의 영향
Effects of Task and Part on Tremor Characteristics in Patients with Essential Tremor
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Essential tremor is a neurological disorder with a tremor of the arms and hands. It is well known that essential tremor is characterized by the postural tremor and the action tremor. There has been no report on the quantitative difference in the characteristics of two tremor types. The purpose of this study was to investigate the possible difference in tremor characteristics of postural and action tremors. Seventeen patients with essential tremor (68.9 ± 7.9years, 7 men, 10 women) participated in this study. Patients performed the tasks of postural maintenance (arms outstretched) and daily actions (spiral drawing). Three-axes (pitch, roll and yaw) gyro sensors were attached on index finger, back of hand and forearm, from which the segment and the joint angular velocities were calculated. Outcome measure was the tremor amplitude defined as the root-mean-square mean of the vector-sum angular velocity at segments and joints. Two-way ANOVA showed that task and joint had main factor on the tremor amplitude (p < 0.05). Post-hoc analysis revealed that tremor amplitude at the metacarpo-phalangeal joint was not affected by task (p > 0.05). However, tremor amplitude at the wrist joint differed among the tasks (p < 0.05), and it was greater in the action tasks than in postural task. Tremor was greater at finger segments than at hand and forearm and it increased in action tasks. The results of this study would be helpful for the understanding and task-specific treatments of the essential tremor.
Abstract
Essential tremor is a neurological disorder with a tremor of the arms and hands. It is well known that essential tremor is characterized by the postural tremor and the action tremor. There has been no report on the quantitative difference in the characteristics of two tremor types. The purpose of this study was to investigate the possible difference in tremor characteristics of postural and action tremors. Seventeen patients with essential tremor (68.9 ± 7.9years, 7 men, 10 women) participated in this study. Patients performed the tasks of postural maintenance (arms outstretched) and daily actions (spiral drawing). Three-axes (pitch, roll and yaw) gyro sensors were attached on index finger, back of hand and forearm, from which the segment and the joint angular velocities were calculated. Outcome measure was the tremor amplitude defined as the root-mean-square mean of the vector-sum angular velocity at segments and joints. Two-way ANOVA showed that task and joint had main factor on the tremor amplitude (p < 0.05). Post-hoc analysis revealed that tremor amplitude at the metacarpo-phalangeal joint was not affected by task (p > 0.05). However, tremor amplitude at the wrist joint differed among the tasks (p < 0.05), and it was greater in the action tasks than in postural task. Tremor was greater at finger segments than at hand and forearm and it increased in action tasks. The results of this study would be helpful for the understanding and task-specific treatments of the essential tremor.
참고문헌 (16)
- G. Deuschl, "Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee", Movement disorders: official journal of the Movement Disorder Society, 13(3), pp.2~23 (1998)
- E.D. Louis, "How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor", Movement disorders : official journal of the Movement Disorder Society, 25, pp.534~541 (2010)
- E.D. Louis, "Essential tremor", Lancet neurology, 4, pp.100~110 (2005)
- K.L. Busenbark, "Is essential tremor benign?", Neurology, 41, pp.1982~1983 (1991)
- T.A. Zesiewicz, "Practice parameter : therapies for essential tremor : report of the Quality Standards Subcommittee of the American Academy of Neurology", Neurology, 64, pp.2008~2020 (2005)
- T.A. Zesiewicz, "Practice parameter : therapies for essential tremor : report of the Quality Standards Subcommittee of the American Academy of Neurology", Neurology, 64, pp.2008~2020 (2005)
- A. Gironell, "Transcranial magnetic stimulation of the cerebellum in essential tremor : a controlled study", Archives of neurology, 59, pp.413~417 (2002)
- K.C. Brennan, "Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study", Mov Disord, 17(2), pp.313~316 (2002)
- G. Nicoletti, "Diffusion tensor MRI changes in cerebellar structures of patients with familial essential tremor", Neurology, 74(12), pp.988~994 (2010)
- S.Y. Wang, "The direction of oscillation in spiral drawings can be used to differentiate distal and proximal arm tremor", Neuroscience Letters, 384, pp.188~192 (2005)
- 이상기, "본태성 진전 환자의 검지에서의 자세성 진전에 대한 감각자극 효과", 의공학회지, 34(3), pp.129~134 (2013), 대한의용생체공학회[DOI]
- 김지원, "파킨슨성 완서증의 손가락 마주치기 속도와 크기에 대한 약물과 뇌심부자극의 효과", 의공학회지, 33(1), pp.47~52 (2012), 대한의용생체공학회
- 김지원, "특발성 파킨슨병 환자의 완서증 정량화를 위한 전완 내회전", 외회전 운동의 각속도 측정, 2009, pp.30(2), 142~146[DOI]
- 김지원, "자이로센서를 이용한 특발성 파킨슨병 환자와 정상인의 손가락 벌렸다 오므리기 동작의 측정과 비교", 의공학회지, 31(3), pp.240~244 (2010), 대한의용생체공학회
- S.E. Fahn, "Parkinson’s Disease and Movement Disorders", pp.271~280 (1993)
- P.H. Mansur, "A review on techniques for tremor recording and quantification", Critical reviews in biomedical engineering, 35, pp.343~362 (2007)