방사모드에 따른 레이저 치료 효과
A Effect of Photo Dynamic Therapy for LAZER Wave Mode
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US Food and Drug Administration (FDA) approved as a innovative cure for cancer, 1996. The effect is death of cancer cells through necrosis, apoptosis. Mainly the Continuous Wave mode (CW) use for PDT Laser. It sting, the question including itch, and etc. Reportedly, the increase of temperature with the perforated edema, ulcer, necrosis. The Thermal relaxation time and Oxygen recovery time is necessary. To give a normal oxygen recovery time of the cell, used Pulse mode. Progress, it was Burst Pulse mode when easing the thermal wake, the simplicity was secured, the PDT effect is good. Excepted in control group CW, Pulse, Burst pulse mode were incubated with various concentrations of 5-aminolevulinic acid hydrochloride (ALA-5). The tumor size reduction CW mode (44%), Pulse mode (48%), Burst pulse mode (53%) at 4 week after PDT with 0.3, 0.3, 0.3 mg/ml of ALA-5. After 4 hours, investigation of 100, 100, 100 J/cm2 laser irradiation. The pulse mode was superior in expirimental data analysis. And it was the Burst pulse mode edge head of a family effect
Abstract
US Food and Drug Administration (FDA) approved as a innovative cure for cancer, 1996. The effect is death of cancer cells through necrosis, apoptosis. Mainly the Continuous Wave mode (CW) use for PDT Laser. It sting, the question including itch, and etc. Reportedly, the increase of temperature with the perforated edema, ulcer, necrosis. The Thermal relaxation time and Oxygen recovery time is necessary. To give a normal oxygen recovery time of the cell, used Pulse mode. Progress, it was Burst Pulse mode when easing the thermal wake, the simplicity was secured, the PDT effect is good. Excepted in control group CW, Pulse, Burst pulse mode were incubated with various concentrations of 5-aminolevulinic acid hydrochloride (ALA-5). The tumor size reduction CW mode (44%), Pulse mode (48%), Burst pulse mode (53%) at 4 week after PDT with 0.3, 0.3, 0.3 mg/ml of ALA-5. After 4 hours, investigation of 100, 100, 100 J/cm2 laser irradiation. The pulse mode was superior in expirimental data analysis. And it was the Burst pulse mode edge head of a family effect
참고문헌 (21)
- Edell ES, "Photodynamic Therapy in the Management of Early Superficial Squamous Cell Carcinoma as an Alternative to Surgical Resection", Chest, 102, pp.1319~1322 (1992)
- Moan J, "Photochemotherapy of Cancer: Experimental Research", 55, pp.931~948 (1992)
- S. G. Rockson, "An Emerging Clinical Cardiovascular role for Photodynamic Therapy", Circulation, 102, pp.591~596 (2000)
- 윤성호, "폐암에서 광역동치료술의 효과", Tuberculosis and Respiratory Diseases, 57(4), pp.358~363 (2004), 대한결핵및호흡기학회
- Hampton JA, "Mechanism of Cell Killing in Photodynamic Therapy using a Novel in vivo", in vitro Light Culture System, 1992, pp.56, 235~243
- S. Hatz, "Measuring the Lifetime of Singlet Oxygen in a Single Cell, Addressing the Issue of Cell Viability", Photochem Photobiol Sci, 6 (2007)
- Morgan. J, "Specific Targeting and Toxicity of Sulphonated Aluminium Phthalocyanine Photosensitised Liposomes Directed to Cells by Monoclonal Antibody in vitro", Br. J Cancer, 59(3), pp.66~70 (1983)
- 이병구, "GafChromic RTQA Film을 이용한 광역학적 치료용 레이저의 선질 측정", 의공학회지, 34(2), pp.73~79 (2013), 대한의용생체공학회[DOI]
- Jacques, S.L., "Laser-Tissue Interactions, Photochemical, Photothermal, and Photomechanical", The Surgical clinics of North America, 72(3), pp.531~558 (1992)
- Kocsis, L., "The Modified Beer-Lambert law Revisited", Phys. Med. Biol, 51(5), pp.91~98 (2006)
- Wobst, P., "Linear Aspects of Changes in Deoxygenated Hemoglobin Concentration and Cytochrome Oxidase Oxidation During Brain Activation", Nerolmage, 13(3), pp.520~530 (2001)
- Meinhardt, M., "Wavelength-Dependent Penetration Depths of Ultraviolet Radiation in Human Skin", Journal of Biomedical Optics, 13(4), pp.044030~ (2008)
- Venugopalam, V., "The Effect of Laser Parameters on the Zone of Thermal Injury Produced by Laser Ablation of Biological Tissue", Am. J. Ophthalmol, 116(1), pp.62~70 (1994)
- Dougherty TJ, "Review Photodynamic Therapy", J Natl Cancer inc, 90(12), pp.889~905 (1998)
- H. S. Lim, "Photo Dynamic Cancer Therapy and Application of Laser" (2010), Gung media(Chung nam National University Press)
- Bogdan Allemann I, "Basics in Dermatological Laser Applications", Curr OProbl Dermatol. Basel Karger, 42, pp.7~23
- Goldberg DJ, "Laser Dermatology" (2005), Springer
- H. S. Lim, "Biomedical Optics and Laser Treatment", Optical Science and Technology, 7, pp.6~13 (2003)
- Tomayko MM, "Determination of Subcutaneous Tumor Size in Athymic(nude)Mice", Cancer Chemother Pharmacol, 24, pp.148~154 (1989)
- P Babilas, "Effect of Light Fractionation and Different Fluence rates on Photodynamic Therapy with 5-aminolaevulinic acid in vivo", Br. J of cancer, 88, pp.1462~1469 (2003)
- Simone Muller, Heinrich, "Enhanced Photodynamic Effects using Fractionated Laser Light", Journal of Photochemistry and Photobiology B : Biology, 42, pp.67~70 (1998)
