Discriminative Power of Seoul Cognitive Status Test in Differentiating Subjective Cognitive Decline, Amnestic Mild Cognitive Impairment, and Dementia Based on CERAD-K Standards
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Background and Purpose: We developed a new digital cognitive assessment called Seoul Cognitive Status Test (SCST), formerly called Inbrain Cognitive Screening Test. The purpose of this study was to validate the clinical utility of the SCST by comparing its scores of those with subjective cognitive decline (SCD), amnestic mild cognitive impairment (aMCI), and dementia diagnosed by the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet (CERAD-K). Methods: All participants (n=296) who completed the CERAD-K, SCST, and Instrumental Activities of Daily Living tests were included in this study. Total score, cognitive domain scores, and subtest scores of the SCST were compared among the 3 groups (SCD, aMCI, and dementia). Additionally, correlations between SCST and CERAD-K subtests were examined. Results: Cognitive domain scores and total score of the SCST showed significant differences among the three groups, with scores being the highest in the order of SCD, aMCI, and dementia (p<0.001). Most subtests of the SCST also showed higher scores in the order of SCD, aMCI, and dementia (p<0.001). However, SCD and aMCI groups showed no significant differences in scores of the Phonemic Word Fluency Test (p=0.083) or Korean Trail Making Test-Elderly version Part A (p=0.434). Additionally, there was no significant difference in the score of Place Recognition (p=0.274) of the Word-Place Association Test between aMCI and dementia groups. Conclusions: In conclusion, differences in total score, cognitive domain scores, and subtest scores of the SCST among the 3 groups of participants diagnosed using CERAD-K confirm the clinical utility of the SCST for cognitive assessment.
Abstract
Background and Purpose: We developed a new digital cognitive assessment called Seoul Cognitive Status Test (SCST), formerly called Inbrain Cognitive Screening Test. The purpose of this study was to validate the clinical utility of the SCST by comparing its scores of those with subjective cognitive decline (SCD), amnestic mild cognitive impairment (aMCI), and dementia diagnosed by the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet (CERAD-K). Methods: All participants (n=296) who completed the CERAD-K, SCST, and Instrumental Activities of Daily Living tests were included in this study. Total score, cognitive domain scores, and subtest scores of the SCST were compared among the 3 groups (SCD, aMCI, and dementia). Additionally, correlations between SCST and CERAD-K subtests were examined. Results: Cognitive domain scores and total score of the SCST showed significant differences among the three groups, with scores being the highest in the order of SCD, aMCI, and dementia (p<0.001). Most subtests of the SCST also showed higher scores in the order of SCD, aMCI, and dementia (p<0.001). However, SCD and aMCI groups showed no significant differences in scores of the Phonemic Word Fluency Test (p=0.083) or Korean Trail Making Test-Elderly version Part A (p=0.434). Additionally, there was no significant difference in the score of Place Recognition (p=0.274) of the Word-Place Association Test between aMCI and dementia groups. Conclusions: In conclusion, differences in total score, cognitive domain scores, and subtest scores of the SCST among the 3 groups of participants diagnosed using CERAD-K confirm the clinical utility of the SCST for cognitive assessment.
참고문헌 (15)
- "World Alzheimer report 2023: reducing dementia risk: never too early, never too late" (2023)[URL]
- Nationwide Survey on Dementia Epidemiology of Korea, "Kim KW", Ministry of Health and Welfare & National Institute of Dementia, ~ (2016)
- Lee JH, "Development of the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet(CERAD-K) : clinical and neuropsychological assessment batteries", J Gerontol B Psychol Sci Soc Sci, 57, pp.47~53 (2002)
- Kang YJ, "Seoul Neuropsychological Screening Battery (SNSB-II)" (2012), Human Brain Research & Consulting Co
- Chin J, "A validation study of the Inbrain CST : a tablet computer-based cognitive screening test for elderly people with cognitive impairment", J Korean Med Sci, 35, pp.e292~ (2020)
- Na S, "Correlation analysis between subtest scores of CERAD-K and a newly developed tablet computer-based digital cognitive test(Inbrain CST)", Front Aging Neurosci, 15, pp.1178324~ (2023)
- Na S, "Diagnostic performance of a tablet computer-based cognitive screening test for identification of amnestic mild cognitive impairment", J Korean Med Sci, 38, pp.e131~ (2023)
- Petersen RC, "Mild cognitive impairment : a concept in evolution", J Intern Med, 275, pp.214~228 (2014)
- Jhoo JH, "Prevalence of dementia and its subtypes in an elderly urban Korean population : results from the Korean Longitudinal Study on Health and Aging(KLoSHA)", Dement Geriatr Cogn Disord, 26, pp.270~276 (2008)
- Jack CR JrBennett DA, "NIA-AA research framework : toward a biological definition of Alzheimer’s disease", Alzheimers Dement, 14, pp.535~562 (2018)
- Park HK, "Clinical characteristics of a nationwide hospital-based registry of mild-to-moderate Alzheimer’s disease patients in Korea : a CREDOS(Clinical Research Center for Dementia of South Korea)study", J Korean Med Sci, 26, pp.1219~1226 (2011)
- Chin J, "Re-standardization of the Korean-Instrumental Activities of Daily Living(K-IADL) : clinical usefulness for various neurodegenerative diseases", Dement Neurocogn Disord, 17, pp.11~22 (2018)
- Kang SJ, "The reliability and validity of the Korean Instrumental Activities of Daily Living(K-IADL)", J Korean Neurol Assoc, 20, pp.8~14 (2002)
- Ku HM, "A study on the reliability and validity of Seoul-Instrumental Activities of Daily Living(S-IADL)", J Korean Neuropsychiatr Assoc, 43, pp.189~199 (2004)
- The Korean Version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet, "Woo JI", Seoul National University Publication and Culture Center, ~ (2015)