Development of the Diagnostic Matrix of the Seoul Cognitive Status Test, Compared to Traditional Paper-and-Pencil Neuropsychological Tests
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background and Purpose: We aimed to develop the diagnostic matrix of the Seoul Cognitive Status Test (SCST) and compare its performance with traditional paper-and-pencil neuropsychological tests, including the Seoul Neuropsychological Screening Battery-II (SNSB-II) and the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-K). Methods: We recruited 197 participants from the head-to-head SCST-SNSB cohort, and 204 participants from the head-to-head SCST-CERAD cohort. They underwent either SNSB-II or CERAD-K, in addition to SCST. The diagnostic matrix was developed by combining cognitive function, determined by neuropsychological tests, and activities of daily living (ADL), determined by Instrumental-ADL scales. Results: The diagnostic agreement between the SCST and the SNSB-II was 83.9% (weighted kappa=0.87). The agreement between the SCST and the CERAD-K was 84.3% (weighted kappa=0.88). In the SCST-SNSB cohort, all differences in SCST scores between the cognitively unimpaired (CU), mild cognitive impairment (MCI), and dementia diagnosed with the SNSB-II were significant in all cognitive domains (all p<0.01), except for the executive domain between CU and MCI (p=0.145). In the SCST-CERAD cohort, all differences in SCST scores between the 3 groups diagnosed with the CERAD-K were significant in all cognitive domains (all p<0.01), except for the language and visuospatial domains between MCI and dementia (p=0.169 and p=0.778, respectively). Conclusions: Our findings suggest that the tablet-based SCST may be another option to traditional paper-and-pencil neuropsychological tests, especially in situations where time and space are relatively limited, and neuropsychological testing specialists are not available.
Abstract
Background and Purpose: We aimed to develop the diagnostic matrix of the Seoul Cognitive Status Test (SCST) and compare its performance with traditional paper-and-pencil neuropsychological tests, including the Seoul Neuropsychological Screening Battery-II (SNSB-II) and the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD-K). Methods: We recruited 197 participants from the head-to-head SCST-SNSB cohort, and 204 participants from the head-to-head SCST-CERAD cohort. They underwent either SNSB-II or CERAD-K, in addition to SCST. The diagnostic matrix was developed by combining cognitive function, determined by neuropsychological tests, and activities of daily living (ADL), determined by Instrumental-ADL scales. Results: The diagnostic agreement between the SCST and the SNSB-II was 83.9% (weighted kappa=0.87). The agreement between the SCST and the CERAD-K was 84.3% (weighted kappa=0.88). In the SCST-SNSB cohort, all differences in SCST scores between the cognitively unimpaired (CU), mild cognitive impairment (MCI), and dementia diagnosed with the SNSB-II were significant in all cognitive domains (all p<0.01), except for the executive domain between CU and MCI (p=0.145). In the SCST-CERAD cohort, all differences in SCST scores between the 3 groups diagnosed with the CERAD-K were significant in all cognitive domains (all p<0.01), except for the language and visuospatial domains between MCI and dementia (p=0.169 and p=0.778, respectively). Conclusions: Our findings suggest that the tablet-based SCST may be another option to traditional paper-and-pencil neuropsychological tests, especially in situations where time and space are relatively limited, and neuropsychological testing specialists are not available.
참고문헌 (26)
- "2023 Alzheimer’s disease facts and figures", Alzheimers Dement, 19, pp.1598~1695 (2023)
- Leicht H, "Net costs of dementia by disease stage", Acta Psychiatr Scand, 124, pp.384~395 (2011)
- Waldemar G, "Access to diagnostic evaluation and treatment for dementia in Europe", Int J Geriatr Psychiatry, 22, pp.47~54 (2007)
- Dubois B, "Timely diagnosis for Alzheimer’s disease : a literature review on benefits and challenges", J Alzheimers Dis, 49, pp.617~631 (2016)
- Then FS, "Differential effects of enriched environment at work on cognitive decline in old age", Neurology, 84, pp.2169~2176 (2015)
- Tsoi KK, "Cognitive tests to detect dementia : a systematic review and meta-analysis", JAMA Intern Med, 175, pp.1450~1458 (2015)
- Breton A, "Cognitive tests for the detection of mild cognitive impairment(MCI), the prodromal stage of dementia : meta-analysis of diagnostic accuracy studies", Int J Geriatr Psychiatry, 34, pp.233~242 (2019)
- Chan JY, "Diagnostic performance of digital cognitive tests for the identification of MCI and dementia : a systematic review", Ageing Res Rev, 72, pp.101506~ (2021)
- Sternin A, "Thirty-five years of computerized cognitive assessment of aging-where are we now?", Diagnostics(Basel), 9, pp.114~ (2019)
- Chin J, "A validation study of the Inbrain CST : a tablet computer-based cognitive screening test for elderly people with cognitive impairment", J Korean Med Sci, 35, pp.e292~ (2020)
- Na S, "Diagnostic performance of a tablet computer-based cognitive screening test for identification of amnestic mild cognitive impairment", J Korean Med Sci, 38, pp.e131~ (2023)
- Na S, "Correlation analysis between subtest scores of CERAD-K and a newly developed tablet computer-based digital cognitive test(Inbrain CST)", Front Aging Neurosci, 15, pp.1178324~ (2023)
- Petersen RC, "Mild cognitive impairment as a diagnostic entity", J Intern Med, 256, pp.183~194 (2004)
- Jack CR Jr, "NIA-AA Research Framework : toward a biological definition of Alzheimer’s disease", Alzheimers Dement, 14, pp.535~562 (2018)
- Fazekas F, "Pathologic correlates of incidental MRI white matter signal hyperintensities", Neurology, 43, pp.1683~1689 (1993)
- Kang Y, "Seoul Neuropsychological Screening Battery. Second Edition (SNSB-II): Professional Manual" (2012), Human Brain Research & Consulting Co
- Lee JH, "Development of the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet(CERAD-K) : clinical and neuropsychological assessment batteries", J Gerontol B Psychol Sci Soc Sci, 57, pp.47~53 (2002)
- Chin J, "Re-standardization of the Korean-Instrumental Activities of Daily Living(K-IADL) : clinical usefulness for various neurodegenerative diseases", Dement Neurocogn Disord, 17, pp.11~22 (2018)
- Ku HM, "A study on the reliability and validity of Seoul-Instrumental Activities of Daily Living(S-IADL)", J Korean Neuropsychiatr Assoc, 43, pp.189~199 (2004)
- Sim J, "The kappa statistic in reliability studies : use, interpretation, and sample size requirements", Phys Ther, 85, pp.257~268 (2005)
- Sullivan GM, "Using effect size—or why the P value is not enough", J Grad Med Educ, 4, pp.279~282 (2012)
- Sawilowsky SS, "New effect size rules of thumb", J Mod Appl Stat Methods, 8, pp.597~599 (2009)
- Ahmed S, "A comparison of screening tools for the assessment of mild cognitive impairment : preliminary findings", Neurocase, 18, pp.336~351 (2012)
- Dwolatzky T, "Validity of a novel computerized cognitive battery for mild cognitive impairment", BMC Geriatr, 3, pp.4~ (2003)
- Doniger GM, "Towards practical cognitive assessment for detection of early dementia : a 30-minute computerized battery discriminates as well as longer testing", Curr Alzheimer Res, 2, pp.117~124 (2005)
- Mundt JC, "Computer-automated dementia screening using a touch-tone telephone", Arch Intern Med, 161, pp.2481~2487 (2001)