본문 바로가기
KERD
논문KCI 등재

재택 자가 항생제 치료 중이던 환아에서 발생한 중심정맥관 관련 Tsukamurella inchonensis 균혈증 1예

A Case of Catheter-Related Bloodstream Infection by Tsukamurella inchonensis in a Pediatric Patient Receiving Home Intravenous Antibiotic Treatment

1

조회

0

다운로드

1

인용

0

참고문헌

키워드

초록

Tsukamurella 속은 산소성으로 약한 항산성을 띠며 가지를 치지 않는 그람양성 막대균이다. Tsukamurella 균속이 중심정맥관관련 균혈증을 일으킨 예가 보고되어 있으며, Corynebacterium 이나 비정형 Mycobacterium로 잘못 동정되기도 하므로 이 균종의 감염은 실제보다 드물게 진단될 것으로 추정한다. 따라서 중심정맥관을 가진 환자에서 혈액배양에서 coryneform 그람양성막대균이 분리되어 중심정맥관관련 균혈증이 의심될 때 Tsukamurella 균종을 감별진단에 넣어야 할 것이다. 저자들은 담도폐쇄증으로간문-장문합술수술을 시행 받은 4세 환아에서 중심정맥관과 연관되어 발생한 T. inchonensis 균혈증을 보고하는 바이다.

Abstract

Bacteria belonging to the genus Tsukamurella are aerobic, gram-positive rods that are weakly acid-fast with no apparent branching. Infections of the Tsukamurella spp. are generally caused by the use of infected medical devices such as central venous catheters. The underreporting of these infections might be attributable to the frequent misdiagnosis of Tsukamurella infections as Corynebacterium or atypical Mycobacterium spp. infections. Therefore, when gram-positive aerobic rods are observed in the blood culture of a patient with a central venous catheter, it is important to consider Tsukamurella as one of the causative organisms. Here, we report the first case of a catheter-related blood stream infection caused by Tsukamurella inchonensis in a 3-yr-old Korean girl with underlying biliary atresia who underwent hepatoportoenterostomy.

참고문헌 (20)

  1. Conville PS, "Nocardia, Rhodococcus, Gordonia, Actinomadura, Streptomyces, and Other Aerobic Actionmycetes, In Manual of clinical microbiology. 9th ed", pp.515~535 (2007), ASM Press
  2. Maalouf R, "First case report of community- acquired pneumonia due to Tsukamurella pulmonis", Ann Intern Med, 150, pp.147~148 (2009)
  3. Alcaide ML, "Cavitary pneumonia secondary to Tsukamurella in an AIDS patient. First case and a review of the literature", J Infect, 49, pp.17~19 (2004)
  4. Larkin JA, "Infection of a knee prosthesis with Tsukamurella species", South Med J, 92, pp.831~832 (1999)
  5. Shaer AJ, "Tsukamurella peritonitis associated with continuous ambulatory peritoneal dialysis", Clin Nephrol, 56, pp.241~246 (2001)
  6. Woo PC, "Tsukamurella conjunctivitis: a novel clinical syndrome", J Clin Microbiol, 41, pp.3368~3371 (2003)
  7. Woo PC, "First report of Tsukamurella keratitis: association between T. tyrosinosolvens and T. pulmonis and ophthalmologic infections", J Clin Microbiol, 47, pp.1953~1956 (2009)
  8. 심효은, "중심정맥관 관련 Tsukamurella pulmonis 균혈증 1예", Annals of Laboratory Medicine, 29(1), pp.41~47 (2009), 대한진단검사의학회
  9. Elshibly S, "Central line-related bacteraemia due to Tsukamurella tyrosinosolvens in a haematology patient", Ulster Med J, 74, pp.43~46 (2005)
  10. Bouza E, "Tsukamurella: a cause of catheter-related bloodstream infections", Eur J Clin Microbiol Infect Dis, 28, pp.203~210 (2009)
  11. Interpretive criteria for identification of bacteria and fungi by DNA target sequencing; approved guideline, "Clinical and Laboratory Standards Institute", Clinical and Laboratory Standards Institute, ~, pp.CLSI document MM18-A (2008)
  12. 이미경, "비정형성 마이코박테리아로 잘못 동정된 Tsukamurella pulmonis 균혈증 1예", Annals of Clinical Microbiology, 13(2), pp.93~97 (2010), 대한임상미생물학회
  13. 박재찬, "복막투석 환자에서 발생한 Tsukamurella tyrosinosolvens 복막염 1예", 대한내과학회지, 76(2), pp.225~228 (2009), 대한내과학회
  14. Lo SF, "Reference intervals for laboratory tests and procedures, In Nelson textbook of pediatrics. 19th ed", pp.2011, Elsevier
  15. Chun J, "EzTaxon: a webbased tool for the identification of prokaryotes based on 16S ribosomal RNA gene sequences", Int J Syst Evol Microbiol, 57, pp.2259~2261 (2007)
  16. Saitou N, "The neighbor-joining method: a new method for reconstructing phylogenetic trees", Mol Biol Evol, 4, pp.406~425 (1987)
  17. Susceptibility testing of Mycobacteria, Nocardiae, and other aerobic actinomycetes; approved standard, "National Committee for Clinical Laboratory Standards", National Committee for Clinical Laboratory Standards, ~, pp.NCCLS document M24-A (2003)
  18. "Guidelines and procedures for monitoring CLABSI" (2011)[URL]
  19. Yassin AF, "Tsukamurella inchonensis sp. nov", Int J Syst Bacteriol, 45, pp.522~527 (1995)
  20. Chong Y, "Tsukamurella inchonensis bacteremia in a patient who ingested Hydrochloric acid", Clin Infect Dis, 24, pp.1267~1268 (1997)

관련 논문AI추천

이 간행물의 다른 논문 (7건)