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임플란트 식립 환자에서 혈소판 풍부혈장의 임상적 응용 사례보고

Case Report of Platelet-Rich Plasma in Patients with Bone Graft at Implant Surgery

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초록

Platelet-rich plasma is an autologous source of platelet-derived growth factor and transforming growth factor that is obtained from sequestering and concentrating platelets by gradient density centrifugation. We have used platelet-rich plasma to evaluate the clinical usefulness for induction of periodontal regeneration in two patients with bone graft at implant surgery, sinus lift procedure, and cyst enucleation. To evaluate the clinical effectiveness, 13 days or 15 day later from bone graft by individuals, histogenetical and cosmetic improvement were evaluated. Patients also were asked about any subjective improvements. As the results, we could observe the histogenetical and cosmetic improvement during treatment, and all cases were good healing and clinical success

Abstract

Platelet-rich plasma is an autologous source of platelet-derived growth factor and transforming growth factor that is obtained from sequestering and concentrating platelets by gradient density centrifugation. We have used platelet-rich plasma to evaluate the clinical usefulness for induction of periodontal regeneration in two patients with bone graft at implant surgery, sinus lift procedure, and cyst enucleation. To evaluate the clinical effectiveness, 13 days or 15 day later from bone graft by individuals, histogenetical and cosmetic improvement were evaluated. Patients also were asked about any subjective improvements. As the results, we could observe the histogenetical and cosmetic improvement during treatment, and all cases were good healing and clinical success

참고문헌 (10)

  1. Calori GM, "Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions: a prospective randomised clinical study on 120 patients", Injury, 39, pp.1391~1402 (2008)
  2. 자가혈소판 풍부 혈장 치료술, "한국보건의료연구원", 보건복지부, 신의료기술평가위원회, ~, pp.신의료기술평가보고서(HTA-2010-27) (2010)
  3. 자가 혈소판 풍부 혈장 치료술, "보건복지부", 보건복지부, 신의료기술평가위원회, ~, pp.신의료기술평가보고서(HTA-2012-35) (2012)
  4. Martínez-Zapata MJ, "Efficacy and safety of the use of autologous plasma rich in platelets for tissue regeneration: a systematic review", Transfusion, 49, pp.44~56 (2009)
  5. 이덕원, "자가혈액에서 농축한 골유도성장인자의 임상응용과 개발의 최근동향", 조직공학과 재생의학, 6(1), pp.259~264 (2009), 한국조직공학과 재생의학회
  6. Hall MP, "Plateletrich plasma: current concepts and application in sports medicine", J Am Acad Orthop Surg, 17, pp.602~608 (2009)
  7. Ha JW, "Use of platelet-rich plasma", 23, pp.452~457 (2001), Korean Assoc Maxillofac Plast Reconstr Surg
  8. Mehta S, "Platelet rich concentrate: basic science and current clinical applications", J Orthop Trauma, 22, pp.432~438 (2008)
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  10. Whitman DH, "Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery", J Oral Maxillofac Surg, 55, pp.1294~1299 (1997)

관련 논문AI추천

혈소판풍부섬유소(platelet rich fibrin) 차단막을 이용한 골 이식술: 치험례김수관, 오지수, 진수영치의학연구원 · Oral Biology Research2012 · 제36권 제2호치과영역에서의 PRP의 유용성김수관, 김정선, 박승철, 박진성, 양성수, 오지수, 이승용, 정미경, 정미애, 정종원치의학연구원 · Oral Biology Research2011 · 제35권 제2호치과 임플란트를 위한 상악동 이식술 시 자가치아 뼈 이식재와 혈소판 농축 혈장의 혼합사용과 효과: 증례연구성일용, 손장호, 전도현, 조영철, 하진희대한통합치과학회 · 대한통합치과학회지2017 · 제6권 제1호치주 골내낭의 치료에 있어 autologous PRF (Platelet Rich Fibrin)와 골이식재의 혼합사용: 증례 보고양승준, 위성현, 이인경, 이정태, 조주현, 한수진대한통합치과학회 · 대한통합치과학회지2016 · 제5권 제1호치조제 결손부에 매식체 식립 시 혈소판 농축 혈장과 골이식술의 사용이 골형성에 미치는 영향에 대한 임상 및 조직 병리학적 연구이종헌, 임성빈, 정의영, 정진형, 홍기석대한치주과학회 · Journal of Periodontal & Implant Science2005 · 제35권 제1호비글견 경골에서 임플란트 식립 시 혈소판 농축 혈장이 골형성에 미치는 영향강성수, 국민석, 박홍주, 심경미, 오희균, 유선열, 정승곤대한구강악안면외과학회 · 대한구강악안면외과학회지2010 · 제36권 제2호

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