임상시험 재 참여에 대한 임상시험 피험자의 이해도 및 만족도의 영향
The influence of trial participants’knowledge and satisfaction on clinical trial re-participation
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This research was conducted to identify the influence of trial participants’general knowledge and satisfaction in a clinical trial on re-participation. From September 2008 to October 2008, a survey questionnaire was distributed to 108 new clinical trial participants in ongoing clinical trials at the investigated Hospital. The participants’general knowledge and satisfaction were measured using a 5-point Likert scale (from 0 to 4) for general attitude towards clinical trials, information source and motive for clinical trial participation,general knowledge of clinical trials, and satisfaction towards one’s own clinical trial. The response rate was 83.3% and 63.3% of respondents agreed with re-participation. We grouped respondents as ‘re-participation acceptor’and ‘re-participation decliner’based on respondents’intent of re-participation. Most re-participation acceptors had more positive attitude towards clinical trial (p<0.05). Similarly, more re-participation acceptors evaluated their general knowledge level positively, especially for‘ background and objective’,‘ frequency of visit and test’and investigational drug dosing’(p<0.05). Among the investigated items, “interest in trials in general”was the most important factor, while “needs for clinical trial into some area”,and“ subjective satisfaction level”were significant effect factors (p<0.05). According to the results, clinical trial staff should make an effort to interest possible participants by providing proper information, and help them recognize the need for clinical trials and the benefits of clinical trials through consistent communication.
Abstract
This research was conducted to identify the influence of trial participants’general knowledge and satisfaction in a clinical trial on re-participation. From September 2008 to October 2008, a survey questionnaire was distributed to 108 new clinical trial participants in ongoing clinical trials at the investigated Hospital. The participants’general knowledge and satisfaction were measured using a 5-point Likert scale (from 0 to 4) for general attitude towards clinical trials, information source and motive for clinical trial participation,general knowledge of clinical trials, and satisfaction towards one’s own clinical trial. The response rate was 83.3% and 63.3% of respondents agreed with re-participation. We grouped respondents as ‘re-participation acceptor’and ‘re-participation decliner’based on respondents’intent of re-participation. Most re-participation acceptors had more positive attitude towards clinical trial (p<0.05). Similarly, more re-participation acceptors evaluated their general knowledge level positively, especially for‘ background and objective’,‘ frequency of visit and test’and investigational drug dosing’(p<0.05). Among the investigated items, “interest in trials in general”was the most important factor, while “needs for clinical trial into some area”,and“ subjective satisfaction level”were significant effect factors (p<0.05). According to the results, clinical trial staff should make an effort to interest possible participants by providing proper information, and help them recognize the need for clinical trials and the benefits of clinical trials through consistent communication.
참고문헌 (15)
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