서울대학교병원의 병용금기 및 특정연령대 금기성분 처방현황

Abstract

The concurrent use of drugs can increase clinical effects, but also increase toxicity or side effects. The Ministry of Health and Welfare announced for . The objectives of this study were estimate the prescribing patterns of contraindication of concurrent use and age-limited drugs in Seoul National University Hospital(SNUH) after an announcement. Out of the outpatient prescriptions in SNUH from January to September 2004, those contraindicated were chosen for the study. The number of prescribing contraindicated drug combinations and age-limited drugs were 513 and 116 cases, respectively. The most prescripted drugs were amitriptyline-selegiline in the contraindication of concurrent use, and topiramate in the age-limited drugs. The rate of contraindication of prescriptions was highest in the department of neurology, rheumatology following. The prescribing of contraindicated drug combinations was relatively decreased, compared with age-limited drugs. This study suggests that investigation about presciption of contraindicated drugs should be continued for avoiding negative drug interaction.