노인의료센터와 일반 병동의 약물유해반응 비교 분석
Comparative Analysis of Adverse Drug Events between Geriatric and Common Wards
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Background : Adverse drug events (ADEs) are medication-related problems that threaten patients’safety and increase the length of stay in hospital settings. Especially, geriatric patients are at high risk for ADEs due to comorbidities, polypharmacy and altered pharmacodynamic and pharmacokinetic properties. The geriatric center (GC) of Seoul National University Bundang Hospital (SNUBH) has a designated charged pharmacist and runs a multi-disciplinary team to prevent ADEs and provide safe treatment. In addition, an ADE reporting and surveillance system has been implemented as an effort to prevent ADEs through all departments in SNUBH. Objectives : In order to assess the effect of a designated-pharmacist in GC on ADE prevention, ADE reports and surveillance signals were collected and analyzed. Methods : A retrospective database review of reported ADEs and ADE surveillance signals was conducted. Reported ADEs were reviewed by pharmacists in the ADE task team to measure causality. Potentially inappropriate medications (PIMs) uses in older adults were determined using the SNUBH geriatric medication guideline. ADE surveillance signals that were judged to be unrelated to ADE by the pharmacists involved were excluded. Results : Among 10,710 inpatients 43 ADEs were reported during the 3-month study period, all of which were from non-GC wards. A total of 77 and 6,819 ADE surveillance signals were reported from 12 geriatric and 708 common ward patients respectively. Polypharmacy were less common and PIMs administered were lower at GC. Conclusion : The frequency of ADE surveillance signals and PIMs uses reported by the multi-disciplinary team involving designated geriatric pharmacists has positive effects on the prevention of ADEs.
Abstract
Background : Adverse drug events (ADEs) are medication-related problems that threaten patients’safety and increase the length of stay in hospital settings. Especially, geriatric patients are at high risk for ADEs due to comorbidities, polypharmacy and altered pharmacodynamic and pharmacokinetic properties. The geriatric center (GC) of Seoul National University Bundang Hospital (SNUBH) has a designated charged pharmacist and runs a multi-disciplinary team to prevent ADEs and provide safe treatment. In addition, an ADE reporting and surveillance system has been implemented as an effort to prevent ADEs through all departments in SNUBH. Objectives : In order to assess the effect of a designated-pharmacist in GC on ADE prevention, ADE reports and surveillance signals were collected and analyzed. Methods : A retrospective database review of reported ADEs and ADE surveillance signals was conducted. Reported ADEs were reviewed by pharmacists in the ADE task team to measure causality. Potentially inappropriate medications (PIMs) uses in older adults were determined using the SNUBH geriatric medication guideline. ADE surveillance signals that were judged to be unrelated to ADE by the pharmacists involved were excluded. Results : Among 10,710 inpatients 43 ADEs were reported during the 3-month study period, all of which were from non-GC wards. A total of 77 and 6,819 ADE surveillance signals were reported from 12 geriatric and 708 common ward patients respectively. Polypharmacy were less common and PIMs administered were lower at GC. Conclusion : The frequency of ADE surveillance signals and PIMs uses reported by the multi-disciplinary team involving designated geriatric pharmacists has positive effects on the prevention of ADEs.
참고문헌 (8)
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