노인의료센터 다학제 팀의 약물 조정이 약물사용 및 약제비 절감에 미치는 효과
The Effects of Medication Reconciliation on Drug Use and Cost-Saving by Multidisciplinary Geriatric Care Team
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Background : Older adults tend to experience multiple chronic conditions on polypharmacy with consequent increase in adverse drug events and medication costs, requiring more medication reconciliation. To date, the effects of medication reconciliation for the inpatients by geriatric pharmacists in multidisciplinary teams have been rarely known in Korea. The purpose of this study was to assess the effects of medication reconciliation by analyzing the changes in prescription and reductions in medication costs for inpatients who received multidisciplinary team care. Methods : Records of patients age 65 and older, admitted to the geriatric center July 1, 2016-June 30, 2017, were retrospectively analyzed in this study. The list of the medications prior to the admission and upon the hospital discharge was obtained from the comprehensive geriatric assessment and electronic medical records, respectively to assess the reduction of the total number of medications, drug duplication, and potentially inappropriate medications (PIM). The cost of drugs was calculated by multiplying the daily price of medicine by the number of days of medication. Results : The mean age of 300 patients was 83.7 (SD 6.9), and 38.7% were males. The patients taking five or more medications were 87.3% before the admission, and 45.0% were mainly diagnosed with infectious disease at admission. With the medication reconciliation, the mean number of medication per patients decreased 10.5 (SD 5.0)-6.5 (SD 3.4) (p 0.001). The number of patients who received the medications listed under PIMs and duplicated was reduced 227-114, and 59-3, respectively (all p 0.001). A total of 458,573 won was saved per person through medication reconciliation. Conclusions : The multidisciplinary team care with the geriatric pharmacist led to safer and more appropriate medication therapy. As a result, it subsequently improved patient safety and medication cost-saving for geriatric patients
Abstract
Background : Older adults tend to experience multiple chronic conditions on polypharmacy with consequent increase in adverse drug events and medication costs, requiring more medication reconciliation. To date, the effects of medication reconciliation for the inpatients by geriatric pharmacists in multidisciplinary teams have been rarely known in Korea. The purpose of this study was to assess the effects of medication reconciliation by analyzing the changes in prescription and reductions in medication costs for inpatients who received multidisciplinary team care. Methods : Records of patients age 65 and older, admitted to the geriatric center July 1, 2016-June 30, 2017, were retrospectively analyzed in this study. The list of the medications prior to the admission and upon the hospital discharge was obtained from the comprehensive geriatric assessment and electronic medical records, respectively to assess the reduction of the total number of medications, drug duplication, and potentially inappropriate medications (PIM). The cost of drugs was calculated by multiplying the daily price of medicine by the number of days of medication. Results : The mean age of 300 patients was 83.7 (SD 6.9), and 38.7% were males. The patients taking five or more medications were 87.3% before the admission, and 45.0% were mainly diagnosed with infectious disease at admission. With the medication reconciliation, the mean number of medication per patients decreased 10.5 (SD 5.0)-6.5 (SD 3.4) (p 0.001). The number of patients who received the medications listed under PIMs and duplicated was reduced 227-114, and 59-3, respectively (all p 0.001). A total of 458,573 won was saved per person through medication reconciliation. Conclusions : The multidisciplinary team care with the geriatric pharmacist led to safer and more appropriate medication therapy. As a result, it subsequently improved patient safety and medication cost-saving for geriatric patients
참고문헌 (22)
- Hilmer SN, "Clinical pharmacology in the geriatric patient", Fundamental & Clinical Pharmacology, 21(3), pp.217~230 (2007)
- Wright RM, "Geriatric pharmacology : safer prescribing for the elderly patient", Journal of the American Podiatric Medical Association, 94(2), pp.90~97 (2004)
- 박윤희, "국립병원의 고령 환자에 대한 약사의 중재역할과 노인의료 활성화에 대한 제언", 병원약사회지, 33(1), pp.31~48 (2016), 한국병원약사회[DOI]
- Anna Millar, "Evaluating the prevalence of potentially inappropriate prescribing in older adults in intermediate care facilities", Int J Clin Pharm, 39(3), pp.527~535 (2017)
- 박태영, "노인의료센터와 일반 병동의 약물유해반응 비교 분석", 병원약사회지, 33(1), pp.20~30 (2016), 한국병원약사회[DOI]
- Scott W. Keith, "A Physician-Focused Intervention to Reduce Potentially Inappropriate Medication Prescribing in Older People", Drugs Aging, 30(2), pp.119~127 (2013)
- McLean AJ, "Aging biology and Geriatric clinical pharmacology", Pharmacol Rev, 56(2), pp.163~184 (2004)
- "Korean statistical information service:Medication cost of Elderly", ~ (2017)
- 이종혜, "개정된 원내 노인부적절약물 목록을 활용한 입원환자의 약물 평가 및 임상적 중재에 의한 회피비용 분석", 병원약사회지, 31(1), pp.629~637 (2014), 한국병원약사회[DOI]
- Victoria Rollason, "Reduction of Polypharmacy in the Elderly-A systematic Review of the Role of the Pharmacist", Drugs Aging, 20(11), pp.814~832 (2003)
- 백안나, "개정된 원내 노인부적절약물 목록을 활용한 외래환자의 약물사용평가 및 약제비 절감효과 분석", 병원약사회지, 31(3), pp.785~794 (2014), 한국병원약사회[DOI]
- Cahir C, "Potentially inappropriate prescribing and cost outcomes for older people : a national population study", Br J Clin Pharmacol, 69(5), pp.543~552 (2010)
- Hill-Taylor B, "Application of the STOPP", START criteria: a systematic review of the prevalence of potentially inappropriate prescribing in older adults, and evidence of clinical, humanistic and economic impact, 2013, pp.38(5), 360~372
- Hudhra K, "Prevalence and factors associated with potentially inappropriate prescriptions among older patients at hospital discharge", J Eval Clin Pract, 22(5), pp.707~713 (2016)
- Getachew H, "Inappropriate prescribing of antithrombotic therapy in Ethiopian elderly population using updated 2015 STOPP", START criteria : a cross-sectional study, 2016, pp.11, 819~827
- Bahat G, "Prevalence of potentially inappropriate prescribing among older adults : a comparison of the Beers 2012and Screening Tool of Older Person’s Prescriptions criteria version 2", Geriatr Gerontol Int, 17(9), pp.1245~1251 (2017)
- Barbara Clyne, "Effectiveness of a Multifaceted Intervention for Potentially Inappropriate Prescribing in Older Patients in Primary Care : A Cluster-Randomized Controlled Trial", Ann Fam Med, 13(6), pp.545~553 (2015)
- T. Kimura, "Potentially inappropriate medications in elderly Japanese patients: effects of pharmacists’assessment and intervention based on Screening Tool of Older Persons’Potentially Inappropriate Prescriptions criteria ver.2", Journal of Clinical Pharmacy and Therapeutics, 42(2), pp.209~214 (2017)
- 이상곤, "일부 농촌지역 재가노인의 낙상 발생률과 사회경제적 비용 추계", Annals of geriatric medicine and research, 15(1), pp.8~19 (2011), 대한노인병학회
- 류재은, "노인포괄평가 시행 전후의 약물 복용 현황 및 처방 변화", 병원약사회지, 25(2), pp.1~12 (2008), 한국병원약사회[DOI]
- Graham Ellis, "Comprehensive geriatric assessment for older adults admitted to hospital", Clinical research ed, 343(7832), pp.1034~ (2011)
- R. Sean Morrison, "Cost Savings Associated With US Hospital Palliative Care Consultation Programs", Arch Intern Med, 168(16), pp.1783~1790 (2008)
