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Influence of R&D intensity on Innovation Performance in the Korean Pharmaceutical Industry: Focusing on the Moderating Effects of R&D Collaboration

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키워드

주제분류경영학

초록

This paper examined the effect of innovation networks comprising research and development (R&D) collaboration on innovation performance of Korean pharmaceutical firms. As co-assigned patents and co-affiliated publications are common technical outcomes of successful R&D collaboration in the pharmaceutical industry, social network analysis technique was applied for analyzing innovation networks through patent and publication data. Results of Social network analysis indicated that a small set of highly innovative firms in the Korean pharmaceutical industry were actively involved in patenting and publishing. And the analysis of structural equation model found the followings: (1) R&D intensity significantly affected patenting, publication and new drug development, (2) the activity of patenting and publishing was positively related with the innovation performance measured by new drug development, and (3) R&D collaboration in terms of degree centrality of co-patent network played significant moderating roles on the relationships among R&D intensity, patenting, and new drug development. These findings are expected to be helpful to researchers as well as policy-makers to devise innovationpromoting policies in the Korean pharmaceutical industry. Discussions and limitations of the study are provided in the last part.

Abstract

This paper examined the effect of innovation networks comprising research and development (R&D) collaboration on innovation performance of Korean pharmaceutical firms. As co-assigned patents and co-affiliated publications are common technical outcomes of successful R&D collaboration in the pharmaceutical industry, social network analysis technique was applied for analyzing innovation networks through patent and publication data. Results of Social network analysis indicated that a small set of highly innovative firms in the Korean pharmaceutical industry were actively involved in patenting and publishing. And the analysis of structural equation model found the followings: (1) R&D intensity significantly affected patenting, publication and new drug development, (2) the activity of patenting and publishing was positively related with the innovation performance measured by new drug development, and (3) R&D collaboration in terms of degree centrality of co-patent network played significant moderating roles on the relationships among R&D intensity, patenting, and new drug development. These findings are expected to be helpful to researchers as well as policy-makers to devise innovationpromoting policies in the Korean pharmaceutical industry. Discussions and limitations of the study are provided in the last part.

참고문헌 (107)

  1. Ahuja, G., "Collaboration networks, structural holes, and innovation: A longitudinal study", Administrative Science Quarterly, 45(3), pp.425~455 (2000)
  2. Austin, D. H., "An event-study approach to measuring innovative output: The case of biotechnology", The American Economic Review, 83(2), pp.253~258 (1993)
  3. Baregheh, A., "Towards a multidisciplinary definition of innovation", Management Decision, 47, pp.1323~1339 (2009)
  4. Barney, J., "Firm resources and sustained competitive advantage", Journal of management, 17(1), pp.99~120 (1991)
  5. Belleflamme, P., "Industrial organization: markets and strategies" (2015), Cambridge University Press
  6. Bommer, M., "Innovation sources of large and small technology-based firms", IEEE Transactions on Engineering Management, 51(1), pp.13~18 (2004)
  7. Bonacich, P., "Factoring and weighting approaches to status scores and clique identification", Journal of Mathematical Sociology, 2, pp.113~120 (1972)
  8. Bonacich, P., "Some unique properties of eigenvector centrality", Social Networks, 29, pp.555~564 (2007)
  9. Borgatti, S. P., "A relational view of information seeking and learning in social networks", Management Science, 49(4), pp.432~445 (2003)
  10. Breschi, S., "Tracing the links between science and technology: An exploratory analysis of scientists’ and inventors’ networks", Research Policy, 39(1), pp.14~26 (2010)
  11. Burt, R. S., "Structural Holes: The Social Structure of Competition" (1995), Harvard University Press
  12. Cantner, U., "Innovator networks and regional knowledge base", Technovation, 30(9), pp.496~507 (2010)
  13. Chan, K. C., "Ranking research productivity in accounting for Asia-Pacific universities", Review of Quantitative Finance and Accounting, 24(1), pp.47~64 (2005)
  14. Chesbrough, H., "Open innovation: The new imperative for creating and profiting from technology" (2006), Harvard Business School Publishing
  15. Cockburn, I. M., "Absorptive capacity, coauthoring behavior, and the organization of research in drug discovery", The Journal of Industrial Economics, 46(2), pp.157~182 (1998)
  16. Cohen, W. M., "Firm Size and the Nature of Innovation within Industries: The Case of Process and Product R&D", Review of Economics and Statistics, 78, pp.232~243 (1996)
  17. Cohen, W. M., "Handbook of Industrial Organization (Volume 2)", pp.1059~1107 (1989), Elsevier
  18. Firm size and R&D intensity: A re-examination, "Cohen, W. M.", National Bureau of Economic Research, ~ (1987)
  19. Comanor, W. S., "Research and competitive product differentiation in the pharmaceutical industry in the United States", Economica, 31(124), pp.372~384 (1964)
  20. Comanor, W. S., "Patent statistics as a measure of technical change", The Journal of Political Economy, 77(3), pp.392~398 (1969)
  21. Cooper, J. R., "A multidimensional approach to the adoption of innovation", Management decision, 36(8), pp.493~502 (1998)
  22. Crane, D., "Social structure in a group of scientists: A test of the ”invisible college” hypothesis", American Sociological Review, 34(3), pp.335~352 (1969)
  23. Cross, R., "Tie and network correlates of individual performance in knowledge-intensive work", Academy of Management Journal, 47(6), pp.928~937 (2004)
  24. Drucker, P., "The discipline of innovation", Harvard Business Review, pp.5~10 (2002)
  25. Dyer, J. H., "The relational view: Cooperative strategy and sources of interorganizational competitive advantage", Academy of management review, 23(4), pp.660~679 (1998)
  26. Echols, A., "Niche and Performance: The Moderating Role of Network Embeddedness", Strategic management journal, 26(3), pp.219~238 (2005)
  27. Fleming, L., "Small worlds and regional innovation", Organization Science, 18(6), pp.938~954 (2007)
  28. Freeman, L. C., "Centrality in social networks conceptual clarification", Social networks, 1(3), pp.215~239 (1979)
  29. Galambos, L., "Pharmaceutical firms and the transition to biotechnology: A study in strategic innovation", Business History Review, 72(2), pp.250~278 (1998)
  30. Garfield, E., "Citation data: Their use as quantitative indicators for science and technology evaluation and policy-making", Science and Public Policy, 19(5), pp.321~327 (1992)
  31. Gay, B., "Innovation and network structural dynamics: Study of the alliance network of a major sector of the biotechnology industry", Research Policy, 34(10), pp.1457~1475 (2005)
  32. Godin, B., "Research and the practice of publication in industries", Research policy, 25(4), pp.587~606 (1996)
  33. Goetze, C., "An empirical enquiry into co-patent networks and their stars: The case of cardiac pacemaker technology", Technovation, 30, pp.436~446 (2010)
  34. Gorraiz, J., "Key factors and considerations in the assessment of international collaboration: a case study for Austria and six countries", Scientometrics, 91(2), pp.417~433 (2012)
  35. Grabowski, H., "Patents, innovation and access to new pharmaceuticals", Journal of International Economic Law, 5(4), pp.849~860 (2002)
  36. Granovetter, M. S., "The strength of weak ties", American journal of sociology, 78(6), pp.1360~1380 (1973)
  37. Grant, R. M., "Toward a knowledge-based theory of the firm", Strategic Management Journal, 17, pp.109~122 (1996)
  38. Griliches, Z., "Productivity, R&D, and the data constraint", The American Economic Review, 84(1), pp.1~23 (1994)
  39. Patents and R&D: Is There A Lag?, "Hall, B. H.", National Bureau of Economic Research, ~ (1984)
  40. Haynie, D. L., "Delinquent peers revisited: Does network structure matter?", American journal of sociology, 106(4), pp.1013~1057 (2001)
  41. Henderson, R., "Measuring competence?: Exploring firm effects in pharmaceutical research", Strategic management journal, 15(S1), pp.63~84 (1994)
  42. Hooper, D., "Structural equation modelling: Guidelines for determining model fit", Electronic Journal of Business Research Methods, 6(1), pp.53~60 (2008)
  43. Hughes, K., "The interpretation and measurement of R&D intensity—A note", Research Policy, 17(5), pp.301~307 (1988)
  44. Jong, S., "When publications lead to products: The open science conundrum in new product development", Research Policy, 43, pp.645~654 (2014)
  45. Juliano, R., "Pharmaceutical innovation and public policy: The case for a new strategy for drug discovery and development", Science and Public Policy, 40(3), pp.393~405 (2013)
  46. Kim, C., "The global research-and-development network and its effect on innovation", Journal of International Marketing, 18(4), pp.43~57 (2010)
  47. Kim, Y., "Executive social capital and its impacts on job promotion", Academy of Management Proceedings: 2002 (Meeting Abstract Supplement), pp.J1~J6 (2002)
  48. 고영희, "기업의 보유 특허 특성과 경제적 활용 가능성에 대한 연구-의료화학산업 특허를 중심으로", 지식경영연구, 14(1), pp.39~56 (2013), 한국지식경영학회[DOI]
  49. 이문재, "Analysis on Time-Lag Effect of Research and Development Investment in the Pharmaceutical Industry in Korea", Osong Public Health and Research Perspectives, 6(4), pp.241~248 (2015), 질병관리청
  50. Levin, R. C., "Appropriating the returns from industrial research and development", Brookings papers on economic activity, 1987(3), pp.783~831 (1987)
  51. Mazzola, E., "Network embeddedness and new product development in the biopharmaceutical industry: The moderating role of open innovation flow", International Journal of Production Economics, 160, pp.106~119 (2015)
  52. Research Network Position and Innovative Performance: Evidence from the Pharmaceutical Industry, "McKelvey, M.", 1~34, pp.Jena Economic Research Papers (2012-021) (2012)
  53. Melin, G., "Studying research collaboration using co-authorships", Scientometrics, 36(3), pp.363~377 (1996)
  54. Merton, R. K., "The Matthew effect in science", Science, 159(3810), pp.56~63 (1968)
  55. Merton, R. K., "The Matthew effect in science, II: Cumulative advantage and the symbolism of intellectual property", Isis, 79(4), pp.606~623 (1988)
  56. Narin, F., "Patents as indicators of corporate technological strength", Research policy, 16(2-4), pp.143~155 (1987)
  57. Newman, M. E., "Coauthorship networks and patterns of scientific collaboration", Proceedings of the National Academy of Sciences of the United States of America, 101(Suppl 1), pp.5200~5205 (2004)
  58. Newman, M. E., "The structure of scientific collaboration networks", Proceedings of the National Academy of Sciences, 98(2), pp.404~409 (2001)
  59. Nunes, P. M., "Is there a linear relationship between R&D intensity and growth? Empirical evidence of non-high-tech vs. high-tech SMEs", Research policy, 41(1), pp.36~53 (2012)
  60. OECD, "The measurement of scientific and technological activities. Proposed Guidelines for Collecting and Interpreting Technological Innovation Data", European Commission and Eurostat, ~ (2005)
  61. Oehme, M., "SME internationalization modes in the German biotechnology industry: The influence of imitation, network position, and international experience", Journal of International Business Studies, 46(6), pp.629~655 (2015)
  62. Owen-Smith, J., "A Comparison of U. S. and European University-Industry Relations in the Life Sciences", Management Science, 48(1), pp.24~43 (2002)
  63. Pakes, A., "Patents and R&D at the firm level: A first report", Economics Letters, 5(4), pp.377~381 (1980)
  64. Pakes, A., "Patent renewal data", Brookings papers on economic activity, Microeconomics, pp.331~410 (1989)
  65. 추기능, "특허의 경제적 수명의 결정요인에 관한 연구 : 갱신자료를 활용한 생존분석", 지식경영연구, 11(1), pp.65~81 (2010), 한국지식경영학회[DOI]
  66. Pavitt, K., "What makes basic research economically useful?", Research policy, 20(2), pp.109~119 (1991)
  67. Penrose, E. T., "The Theory of the Growth of the Firm" (1995), Oxford University Press
  68. Pisano, G. P., "Science business: The promise, the reality, and the future of biotech" (2006), Harvard Business Press
  69. Porter, M. E., "Competitive advantage: Creating and sustaining superior performance" (1998), Free press
  70. Powell, W. W., "Inter-organizational collaboration in the biotechnology industry", Journal of Institutional and Theoretical Economics(JITE), 1996, pp.151(1), 197~215
  71. Powell, W. W., "Interorganizational collaboration and the locus of innovation: Networks of learning in biotechnology", Administrative science quarterly, 41(1), pp.116~145 (1996)
  72. Powell, W. W., "Network position and firm performance: Organizational returns to collaboration in the biotechnology industry", Research in the Sociology of Organizations, 16(1), pp.129~159 (1999)
  73. Rampersad, G., "Managing innovation networks: Exploratory evidence from ICT, biotechnology and nanotechnology networks", Industrial Marketing Management, 39(5), pp.793~805 (2010)
  74. The Definition and Measurement of Innovation, "Rogers, M.", Melbourne Institute of Applied Economic and Social Research, ~, pp.No. 10 (1998), 98
  75. Rosenberg, N., "Why do firms do basic research (with their own money)?", Research policy, 19(2), pp.165~174 (1990)
  76. Salter, A., "Sources of ideas for innovation in engineering design", Research policy, 32(8), pp.1309~1324 (2003)
  77. Scherer, F. M., "Firm size, market structure, opportunity, and the output of patented inventions", The American Economic Review, 55(5), pp.1097~1125 (1965)
  78. Scherer, F. M., "Handbook of the Economics of Innovation (1)", pp.539~574 (2010), Elsevier
  79. Schermelleh-Engel, K., "Evaluating the fit of structural equation models: Tests of significance and descriptive goodness-of-fit measures", Methods of Psychological Research Online, 8(2), pp.23~74 (2003)
  80. Schmookler, J., "Determinants of inventive activity", The American Economic Review, 52(2), pp.165~176 (1962)
  81. Schmookler, J., "Invention and economic growth" (1966), Harvard University Press
  82. Schumacker, R., "A beginner’s guide to structural equation modeling" (2010), Routledge
  83. Schumpeter, J., "Capitalism, socialism and democracy" (1942), HarperCollins
  84. Schumpeter, J. A., "The Theory of Economic Development: An Inquiry Into Profits, Capital, Credit, Interest, and the Business Cycle" (2012), Transaction Publishers
  85. Scott, J., "Social network analysis" (2010), SAGE Publications Ltd
  86. Singh, J., "Collaborative networks as determinants of knowledge diffusion patterns", Management Science, 51(5), pp.756~770 (2005)
  87. Soh, P. H., "Networks of innovators: a longitudinal perspective", Research policy, 32(9), pp.1569~1588 (2003)
  88. Sohn, D., "Effects of R&D and patents on the financial performance of Korean venture firms", Asian Journal of Technology Innovation, 18(2), pp.169~185 (2010)
  89. Sternitzke, C., "Knowledge sources, patent protection, and commercialization of pharmaceutical innovations", Research policy, 39(6), pp.810~821 (2010)
  90. Stuart, T. E., "Vertical alliance networks: The case of university-biotechnology-pharmaceutical alliance chains", Research Policy, 36(4), pp.477~498 (2007)
  91. Sykes, R., "Being a modern pharmaceutical company involves making information available on clinical trial programmes", British Medical Journal, 317(7167), pp.1172~1180 (1998)
  92. Teece, D. J., "Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy", Research Policy, 15(6), pp.285~305 (1986)
  93. Trajtenberg, M., "A penny for your quotes: patent citations and the value of innovations", The RAND Journal of Economics, 21(1), pp.172~187 (1990)
  94. Tsai, W., "Knowledge transfer in intraorganizational networks: Effects of network position and absorptive capacity on business unit innovation and performance", Academy of Management Journal, 44(5), pp.996~1004 (2001)
  95. Uddin, S., "Network Effects on Scientific Collaborations", PLoS ONE, 8(2), pp.e57546~ (2013)
  96. Van Looy, B., "Publication and patent behavior of academic researchers: Conflicting, reinforcing or merely co-existing?", Research policy, 35(4), pp.596~608 (2006)
  97. Uzzi, B., "The sources and consequences of embeddedness for the economic performance of organizations: The network effect", American Sociological Review, 61(4), pp.674~698 (1996)
  98. Wager, E., "Good publication practice for pharmaceutical companies", Current Medical Research and Opinion, 19(3), pp.149~154 (2003)
  99. Walker, G., "Social capital, structural holes and the formation of an industry network", Organization Science, 8(2), pp.109~125 (1997)
  100. Wang, J., "The analysis and evaluation of knowledge efficiency in research groups", Journal of the American Society for Information Science and Technology, 56(11), pp.1217~1226 (2005)
  101. Wang, N., "The lag structure of the relationship between patenting and internal R&D revisited", Research Policy, 43(8), pp.1275~1285 (2014)
  102. Wasserman, S., "Social network analysis: Methods and applications" (2009), Cambridge university press
  103. Williamson, O. E., "Transaction-cost economics: the governance of contractual relations", Journal of law and economics, 22(2), pp.233~261 (1979)
  104. Williamson, O. E., "Handbook of industrial organization (1)", pp.135~182 (1989)
  105. Wright, S., "The method of path coefficients", The Annals of Mathematical Statistics, 5(3), pp.161~215 (1934)
  106. Zaheer, A., "Benefiting from network position: firm capabilities, structural holes, and performance", Strategic Management Journal, 26(9), pp.809~825 (2005)
  107. Zeng, S. X., "Relationship between cooperation networks and innovation performance of SMEs", Technovation, 30(3), pp.181~194 (2010)

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