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Development of Halo Nevus Around Nevus Spilusas a Central Nevus, and the Concurrent Vitiligo

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초록

Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of the upper dermis in the depigmented lesions. We report here on a 13-year-old boy who showed a depigmented zone around a nevus spilus on the right side of his neck with simultaneous vitiligo lesions on the face.

Abstract

Halo nevus is a benign melanocytic nevus that is surrounded by a hypopigmented zone. The most frequent association with halo nevus is vitiligo, and this also appears in nearby regions, as well as at other remote sites. Although the mechanism for developing the depigmentation around nevus spilus is uncertain an immunologic process may be responsible for the finding of inflammatory infiltrates of the upper dermis in the depigmented lesions. We report here on a 13-year-old boy who showed a depigmented zone around a nevus spilus on the right side of his neck with simultaneous vitiligo lesions on the face.

참고문헌 (10)

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  3. Guerra-Tapia A, "Periocular vitiligo with onset around a congenital divided nevus of the eyelid", Pediatr Dermatol, 22, pp.427~429 (2005)
  4. Brandt O, "Halo dermatitis followed by the development of vitiligo associated with Sutton's nevi", J Am Acad Dermatol, 52(5), pp.S101~S104 (2005)
  5. Zeff RA, "The immune response in halo nevi", J Am Acad Dermatol, 37, pp.620~624 (1997)
  6. Reed RJ, "Common and uncommon melanocytic nevi and borderline melanomas", Semin Oncol, 2, pp.119~147 (1975)
  7. Mooney MA, "Halo nevus or halo phenomenon? A study of 142 cases", J Cutan Pathol, 22, pp.342~348 (1995)
  8. Schallreuter KU, "Molecular evidence that halo in Sutton's naevus is not vitiligo", Arch Dermatol Res, 295, pp.223~228 (2003)
  9. de Vijlder HC, "Difference in pathogenesis between vitiligo vulgaris and halo nevi associated with vitiligo is supported by an HLA association study", Pigment Cell Res, 17, pp.270~274 (2004)
  10. Shin JH, "A case of giant congenital nevocytic nevus with neurotization and onset of vitiligo", J Eur Acad Dermatol Venereol, 16, pp.384~386 (2002)

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