인지장애 선별을 위한 K-ACE 표준화 연구: 신뢰도, 타당도, 규준치 개발
A Standardization Study on the Korean Version of the Addenbrook’s Cognitive Examination Revised (K-ACE) as a Cognitive Impairment Screening Instrument: Reliability, Validity and Normative Data
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Background: Addenbrooke’s Cognitive Examination-Revised (ACE-R) is a brief but sensitive and specific test for screening cognitive impairment. The clinical need for brief, inexpensive, and sensitive cognitive screening tools is well acknowledged. The aims of this study were to develop a Korean version of the ACE-R (K-ACE) and to obtain normative data for community-dwelling, apparently healthy adults. Methods: The ACE-R was translated and modified to produce the K-ACE. Some items that were considered less familiar to Koreans were replaced with “Korean-friendly” items. Back-translation was performed. The K-ACE was administered to 422 of 480 subjects who were recruited from stroke- and dementia-free adults living in Ansan-si, Gyeonggi-do, by systematic random sampling. The Korean version of the Short Blessed Test (SBT-K) was also completed by 85 of the subjects. We examined the internal consistency, reliability, and validity of the K-ACE. The influences of age, sex, and education level on K-ACE score were also evaluated. Results: The internal consistency of the K-ACE was high (Cronbach’s alpha=0.854), and the test–retest and interrater reliability were also very good (coefficient=0.929 and 0.984, respectively). The validity of the K-ACE was high through correlations between K-ACE and K-MMSE (r=0.939, p<0.01) and SBT-K (r=-0.871, p<0.01). Male, younger, and highly educated subjects had higher K-ACE scores on univariate analysis. Age and education level, but not sex, were significantly correlated with the score on stepwise multiple regression analysis. Therefore, normative data relative to age and education level were obtained. Conclusions: The K-ACE was found to be a brief, reliable, and valid screening test battery for cognitive dysfunction. We were able to determine the norms for the K-ACE for community-dwelling, middle-aged and elderly people.
Abstract
Background: Addenbrooke’s Cognitive Examination-Revised (ACE-R) is a brief but sensitive and specific test for screening cognitive impairment. The clinical need for brief, inexpensive, and sensitive cognitive screening tools is well acknowledged. The aims of this study were to develop a Korean version of the ACE-R (K-ACE) and to obtain normative data for community-dwelling, apparently healthy adults. Methods: The ACE-R was translated and modified to produce the K-ACE. Some items that were considered less familiar to Koreans were replaced with “Korean-friendly” items. Back-translation was performed. The K-ACE was administered to 422 of 480 subjects who were recruited from stroke- and dementia-free adults living in Ansan-si, Gyeonggi-do, by systematic random sampling. The Korean version of the Short Blessed Test (SBT-K) was also completed by 85 of the subjects. We examined the internal consistency, reliability, and validity of the K-ACE. The influences of age, sex, and education level on K-ACE score were also evaluated. Results: The internal consistency of the K-ACE was high (Cronbach’s alpha=0.854), and the test–retest and interrater reliability were also very good (coefficient=0.929 and 0.984, respectively). The validity of the K-ACE was high through correlations between K-ACE and K-MMSE (r=0.939, p<0.01) and SBT-K (r=-0.871, p<0.01). Male, younger, and highly educated subjects had higher K-ACE scores on univariate analysis. Age and education level, but not sex, were significantly correlated with the score on stepwise multiple regression analysis. Therefore, normative data relative to age and education level were obtained. Conclusions: The K-ACE was found to be a brief, reliable, and valid screening test battery for cognitive dysfunction. We were able to determine the norms for the K-ACE for community-dwelling, middle-aged and elderly people.
참고문헌 (29)
- McKeith IG, "An evaluation of the predictive validity and inter-rater reliability of clinical diagnostic criteria for senile dementia of Lewy body type", Neurology, 44, pp.872~877 (1994)
- Neary D, "Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria", Neurology, 51, pp.1546~1554 (1998)
- Gifford DR, "Evaluating dementia screening tests: methodologic standards to rate their performance", Neurology, 52, pp.224~227 (1999)
- Mathuranath PS, "A brief cognitive test battery to differentiate Alzheimer’s disease and frontotemporal dementia", Neurology, 55, pp.1613~1620 (2000)
- Folstein MF, ""Mini-mental state. "A practical method for grading the cognitive state of patients for the clinician", J Psychiatr Res, 12, pp.189~198 (1975)
- Morris JC, "Clinical dementia rating training and reliability in multicenter studies: the Alzheimer’s Disease Cooperative Study experience", Neurology, 48, pp.1508~1510 (1997)
- Morris JC, "The Clinical Dementia Rating(CDR): current version and scoring rules", Neurology, 43, pp.2412~2414 (1993)
- Reisberg B, "The Global deterioration scale for assessment of primary degenerative dementia", Am J Psychiatry, 139, pp.1136~1139 (1982)
- Tombaugh TN, "The mini-mental state examination: a comprehensive review", J Am Geriatr Soc, 40, pp.922~935 (1992)
- Feher EP, "Establishing the limits of the Mini-Mental State: Examination of subtests", Arch Neurol, 49, pp.87~92 (1992)
- Greene JD, "Analysis of the episodic memory deficit in early Alzheimer’s disease: evidence from the doors and people test", Neuropsychologia, 34, pp.537~551 (1996)
- Gregory CA, "Can frontotemporal dementia and Alzheimer’s disease be differentiated using a brief battery of tests?", Int J Geriatr Psychiatry, 12, pp.375~383 (1997)
- Nelson A, "Bedside cognitive screening instrument: A critical assessment", J Nerv Ment Dis, 174, pp.73~83 (1986)
- Hodges JR, "The differentiation of semantic dementia and frontal love dementia (temporal and frontal variants of frontotemporal dementia) from early Alzheimer’s disease: a comparative neuropsychological study", Neuropsychology, 13, pp.31~40 (1999)
- Hodges JR, "Semantic dementia. Progressive fluent aphasia with temporal lobe atrophy", Brain, 115, pp.1783~1806 (1992)
- Mathuranath PS, "A brief cognitive test battery to differentiate Alzheimer’s disease and frontotemporal dementia", Neurology, 55, pp.1613~1620 (2002)
- Bier JC, "Is the Addenbrooke’s Cognitive Examination effective to detect frontotemporal dementia?", J Neurol, 251, pp.428~431 (2004)
- Mathuranath PS, "Adaptation of the ACE for a Malayalam speaking population in southern India", Int J Geriatr Psychiatry, 19, pp.1188~1194 (2004)
- Garcia-Caballero A, "Validation of the Spanish version of the Addenbrooke’s Cognitive Examination in a rural community in Spain", Int J Geriatr Psychiatry, 21, pp.239~245 (2006)
- Mioshi E, "The Addenbrooke’s Cognitive Examination Revised(ACE-R): a brief cognitive test battery for dementia screening", Int J Geriatr Psychiatry, 21, pp.1078~1085 (2006)
- Guillemin F, "Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines", J Clin Epidemiol, 46, pp.1417~1432 (1993)
- Kang YW, "A validity study on the Korean Mini-Mental State Examination(K-MMSE) in dementia patients", J Korean Neurol Assoc, 15, pp.300~307 (1997)
- 송호정, "한국 노인의 숫자폭 및 시공간폭 검사 표준화 연구", 한국심리학회지 임상, 25(2), pp.505~532 (2006), 한국임상심리학회
- Pauker JD, "Constructing overlapping cell tables to maximize the clinical usefulness of normative data: rational and an example from neuropsychology", J Clin Psychol, 44, pp.930~933 (1988)
- Katzman R, "Schechter R, Schimmel H. Validation of a short Orientation-Memory-Concentration Test of cognitive impairment", Am J Psychiatry, 140, pp.734~739 (1983)
- Lee DY, "Reliability and validity of the korean version of Short Blessed Test (SBT-K) as a dementia screening instrument", J Korean Neuropsychiatr Assoc, 28, pp.1365~1374 (1999)
- Lezak MD, "Neuropsychological assessment. 3rd ed", pp.155~156 (1995), Oxford University press
- Mckhann G, "Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s disease", Neurology, 34, pp.989~944 (1984)
- 정슬기, "지역사회 주민을 대상으로 한 K-MMSE 및 K-mMMSE 정상 규준치 연구", 대한신경과학회지, 25(1), pp.1~9 (2007), 대한신경과학회